| Full name: acyl-CoA synthetase bubblegum family member 2 | Alias Symbol: BGR|PRTD-NY3|DKFZp434K1635 | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 81616 | HGNC ID: HGNC:24174 | Ensembl Gene: ENSG00000130377 | OMIM ID: 614363 |
| Drug and gene relationship at DGIdb | |||
ACSBG2 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa03320 | PPAR signaling pathway | |
| hsa04920 | Adipocytokine signaling pathway |
Expression of ACSBG2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ACSBG2 | 81616 | 221716_s_at | -0.0310 | 0.9360 | |
| GSE20347 | ACSBG2 | 81616 | 221716_s_at | 0.0648 | 0.3857 | |
| GSE23400 | ACSBG2 | 81616 | 221716_s_at | 0.0123 | 0.7784 | |
| GSE26886 | ACSBG2 | 81616 | 221716_s_at | 0.0362 | 0.7730 | |
| GSE29001 | ACSBG2 | 81616 | 221716_s_at | -0.2275 | 0.1953 | |
| GSE38129 | ACSBG2 | 81616 | 221716_s_at | -0.0206 | 0.8769 | |
| GSE45670 | ACSBG2 | 81616 | 221716_s_at | 0.0661 | 0.5485 | |
| GSE53622 | ACSBG2 | 81616 | 65170 | 0.2554 | 0.0249 | |
| GSE53624 | ACSBG2 | 81616 | 65170 | 0.5280 | 0.0000 | |
| GSE63941 | ACSBG2 | 81616 | 221716_s_at | 0.3501 | 0.0467 | |
| GSE77861 | ACSBG2 | 81616 | 221716_s_at | -0.0906 | 0.6640 | |
| GSE97050 | ACSBG2 | 81616 | A_23_P131050 | 0.3489 | 0.2260 | |
| TCGA | ACSBG2 | 81616 | RNAseq | -0.5603 | 0.2414 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ACSBG2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ACSBG2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ACSBG2 | 81616 | 5 | 3 | 22 | |
| GSE20123 | ACSBG2 | 81616 | 4 | 2 | 24 | |
| GSE43470 | ACSBG2 | 81616 | 2 | 6 | 35 | |
| GSE46452 | ACSBG2 | 81616 | 47 | 1 | 11 | |
| GSE47630 | ACSBG2 | 81616 | 5 | 7 | 28 | |
| GSE54993 | ACSBG2 | 81616 | 16 | 3 | 51 | |
| GSE54994 | ACSBG2 | 81616 | 6 | 16 | 31 | |
| GSE60625 | ACSBG2 | 81616 | 9 | 0 | 2 | |
| GSE74703 | ACSBG2 | 81616 | 2 | 4 | 30 | |
| GSE74704 | ACSBG2 | 81616 | 1 | 2 | 17 | |
| TCGA | ACSBG2 | 81616 | 10 | 19 | 67 |
Total number of gains: 107; Total number of losses: 63; Total Number of normals: 318.
Somatic mutations of ACSBG2:
Generating mutation plots.
Highly correlated genes for ACSBG2:
Showing top 20/527 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ACSBG2 | DMC1 | 0.771665 | 3 | 0 | 3 |
| ACSBG2 | TERT | 0.765334 | 3 | 0 | 3 |
| ACSBG2 | CACNA1F | 0.732747 | 4 | 0 | 4 |
| ACSBG2 | GML | 0.731249 | 6 | 0 | 6 |
| ACSBG2 | FASLG | 0.720891 | 4 | 0 | 3 |
| ACSBG2 | BTNL8 | 0.71311 | 5 | 0 | 5 |
| ACSBG2 | FOLH1 | 0.708817 | 5 | 0 | 5 |
| ACSBG2 | FSCN2 | 0.707515 | 3 | 0 | 3 |
| ACSBG2 | TNR | 0.70723 | 5 | 0 | 5 |
| ACSBG2 | FFAR2 | 0.702034 | 3 | 0 | 3 |
| ACSBG2 | KIR3DL3 | 0.694418 | 7 | 0 | 6 |
| ACSBG2 | CCL25 | 0.692137 | 7 | 0 | 6 |
| ACSBG2 | BMP15 | 0.688356 | 5 | 0 | 5 |
| ACSBG2 | ARVCF | 0.684519 | 4 | 0 | 3 |
| ACSBG2 | ALAS2 | 0.682908 | 3 | 0 | 3 |
| ACSBG2 | CHIT1 | 0.682341 | 3 | 0 | 3 |
| ACSBG2 | FABP7 | 0.681742 | 3 | 0 | 3 |
| ACSBG2 | CACNG8 | 0.681502 | 3 | 0 | 3 |
| ACSBG2 | OR52A1 | 0.680603 | 5 | 0 | 5 |
| ACSBG2 | GJD2 | 0.680114 | 6 | 0 | 5 |
For details and further investigation, click here
