| Full name: calpain 11 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 6p21.1 | ||
| Entrez ID: 11131 | HGNC ID: HGNC:1478 | Ensembl Gene: ENSG00000137225 | OMIM ID: 604822 |
| Drug and gene relationship at DGIdb | |||
Expression of CAPN11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CAPN11 | 11131 | 207962_at | -0.1599 | 0.3862 | |
| GSE20347 | CAPN11 | 11131 | 207962_at | -0.0700 | 0.2443 | |
| GSE23400 | CAPN11 | 11131 | 207962_at | -0.0907 | 0.0003 | |
| GSE26886 | CAPN11 | 11131 | 207962_at | -0.1302 | 0.1382 | |
| GSE29001 | CAPN11 | 11131 | 207962_at | -0.2416 | 0.1627 | |
| GSE38129 | CAPN11 | 11131 | 207962_at | -0.0978 | 0.0943 | |
| GSE45670 | CAPN11 | 11131 | 207962_at | 0.0232 | 0.7952 | |
| GSE53622 | CAPN11 | 11131 | 42424 | 0.0894 | 0.5550 | |
| GSE53624 | CAPN11 | 11131 | 42424 | 0.2040 | 0.1656 | |
| GSE63941 | CAPN11 | 11131 | 207962_at | 0.1570 | 0.2055 | |
| GSE77861 | CAPN11 | 11131 | 207962_at | -0.1300 | 0.2390 | |
| SRP133303 | CAPN11 | 11131 | RNAseq | -0.0119 | 0.9744 | |
| SRP159526 | CAPN11 | 11131 | RNAseq | 0.4752 | 0.5032 | |
| SRP219564 | CAPN11 | 11131 | RNAseq | 0.2473 | 0.5498 | |
| TCGA | CAPN11 | 11131 | RNAseq | 0.1983 | 0.6362 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CAPN11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CAPN11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CAPN11 | 11131 | 8 | 0 | 22 | |
| GSE20123 | CAPN11 | 11131 | 8 | 0 | 22 | |
| GSE43470 | CAPN11 | 11131 | 6 | 0 | 37 | |
| GSE46452 | CAPN11 | 11131 | 3 | 9 | 47 | |
| GSE47630 | CAPN11 | 11131 | 8 | 4 | 28 | |
| GSE54993 | CAPN11 | 11131 | 3 | 2 | 65 | |
| GSE54994 | CAPN11 | 11131 | 9 | 3 | 41 | |
| GSE60625 | CAPN11 | 11131 | 0 | 1 | 10 | |
| GSE74703 | CAPN11 | 11131 | 6 | 0 | 30 | |
| GSE74704 | CAPN11 | 11131 | 4 | 0 | 16 | |
| TCGA | CAPN11 | 11131 | 21 | 13 | 62 |
Total number of gains: 76; Total number of losses: 32; Total Number of normals: 380.
Somatic mutations of CAPN11:
Generating mutation plots.
Highly correlated genes for CAPN11:
Showing top 20/680 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CAPN11 | ZMAT4 | 0.73955 | 3 | 0 | 3 |
| CAPN11 | RHAG | 0.716688 | 3 | 0 | 3 |
| CAPN11 | FBP2 | 0.715627 | 4 | 0 | 4 |
| CAPN11 | GRPR | 0.713376 | 4 | 0 | 3 |
| CAPN11 | NAALADL1 | 0.708498 | 3 | 0 | 3 |
| CAPN11 | ZPBP | 0.706688 | 3 | 0 | 3 |
| CAPN11 | SLC22A2 | 0.703626 | 3 | 0 | 3 |
| CAPN11 | MROH7 | 0.702354 | 3 | 0 | 3 |
| CAPN11 | APOBEC1 | 0.699599 | 4 | 0 | 4 |
| CAPN11 | TMEM114 | 0.692643 | 3 | 0 | 3 |
| CAPN11 | GJD2 | 0.690589 | 4 | 0 | 4 |
| CAPN11 | HIPK3 | 0.685859 | 3 | 0 | 3 |
| CAPN11 | PHEX | 0.682175 | 3 | 0 | 3 |
| CAPN11 | IFNA21 | 0.68133 | 4 | 0 | 4 |
| CAPN11 | S100A1 | 0.676997 | 4 | 0 | 4 |
| CAPN11 | CLCNKB | 0.676682 | 4 | 0 | 3 |
| CAPN11 | PRDM11 | 0.675847 | 4 | 0 | 3 |
| CAPN11 | BFSP2 | 0.67305 | 4 | 0 | 3 |
| CAPN11 | FUT9 | 0.67299 | 3 | 0 | 3 |
| CAPN11 | MOBP | 0.669178 | 5 | 0 | 4 |
For details and further investigation, click here
