| Full name: G protein-coupled receptor 21 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 9q33.2 | ||
| Entrez ID: 2844 | HGNC ID: HGNC:4476 | Ensembl Gene: ENSG00000188394 | OMIM ID: 601909 |
| Drug and gene relationship at DGIdb | |||
Expression of GPR21:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GPR21 | 2844 | 221294_at | 0.0853 | 0.7944 | |
| GSE20347 | GPR21 | 2844 | 221294_at | -0.0221 | 0.8053 | |
| GSE23400 | GPR21 | 2844 | 221294_at | -0.1015 | 0.0038 | |
| GSE26886 | GPR21 | 2844 | 221294_at | -0.1083 | 0.4937 | |
| GSE29001 | GPR21 | 2844 | 221294_at | -0.1429 | 0.4452 | |
| GSE38129 | GPR21 | 2844 | 221294_at | -0.1190 | 0.1601 | |
| GSE45670 | GPR21 | 2844 | 221294_at | 0.0640 | 0.4578 | |
| GSE63941 | GPR21 | 2844 | 221294_at | 0.1785 | 0.3093 | |
| GSE77861 | GPR21 | 2844 | 221294_at | 0.0482 | 0.6226 | |
| GSE97050 | GPR21 | 2844 | A_23_P135219 | 0.1243 | 0.6917 | |
| SRP133303 | GPR21 | 2844 | RNAseq | -0.2826 | 0.1698 | |
| TCGA | GPR21 | 2844 | RNAseq | -0.0804 | 0.8223 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GPR21 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of GPR21:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GPR21 | 2844 | 3 | 8 | 19 | |
| GSE20123 | GPR21 | 2844 | 3 | 8 | 19 | |
| GSE43470 | GPR21 | 2844 | 5 | 4 | 34 | |
| GSE46452 | GPR21 | 2844 | 6 | 13 | 40 | |
| GSE47630 | GPR21 | 2844 | 3 | 16 | 21 | |
| GSE54993 | GPR21 | 2844 | 3 | 3 | 64 | |
| GSE54994 | GPR21 | 2844 | 9 | 10 | 34 | |
| GSE60625 | GPR21 | 2844 | 0 | 0 | 11 | |
| GSE74703 | GPR21 | 2844 | 5 | 3 | 28 | |
| GSE74704 | GPR21 | 2844 | 2 | 6 | 12 | |
| TCGA | GPR21 | 2844 | 27 | 24 | 45 |
Total number of gains: 66; Total number of losses: 95; Total Number of normals: 327.
Somatic mutations of GPR21:
Generating mutation plots.
Highly correlated genes for GPR21:
Showing top 20/804 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GPR21 | EDA2R | 0.715033 | 4 | 0 | 4 |
| GPR21 | SYT13 | 0.70012 | 3 | 0 | 3 |
| GPR21 | DEFA4 | 0.699345 | 3 | 0 | 3 |
| GPR21 | MAP3K12 | 0.692781 | 3 | 0 | 3 |
| GPR21 | GJD2 | 0.688585 | 4 | 0 | 4 |
| GPR21 | GRIP2 | 0.683774 | 6 | 0 | 6 |
| GPR21 | IL18BP | 0.682171 | 4 | 0 | 4 |
| GPR21 | UBE2D4 | 0.679651 | 3 | 0 | 3 |
| GPR21 | GFRA3 | 0.676156 | 3 | 0 | 3 |
| GPR21 | ATG10 | 0.672226 | 4 | 0 | 4 |
| GPR21 | CIITA | 0.670776 | 5 | 0 | 5 |
| GPR21 | NPAP1 | 0.670021 | 4 | 0 | 4 |
| GPR21 | MAS1 | 0.667448 | 4 | 0 | 4 |
| GPR21 | OR6A2 | 0.662021 | 5 | 0 | 4 |
| GPR21 | SLC4A1 | 0.657758 | 6 | 0 | 6 |
| GPR21 | FAM217A | 0.657746 | 3 | 0 | 3 |
| GPR21 | MYO7B | 0.657715 | 5 | 0 | 3 |
| GPR21 | TMPRSS5 | 0.655459 | 7 | 0 | 7 |
| GPR21 | BLK | 0.654985 | 4 | 0 | 4 |
| GPR21 | GIT1 | 0.654505 | 3 | 0 | 3 |
For details and further investigation, click here
