PAPOLB

 

Full name: poly(A) polymerase beta Alias Symbol: PAPT
Type: protein-coding gene Cytoband: 7p22.1
Entrez ID: 56903 HGNC ID: HGNC:15970 Ensembl Gene: ENSG00000218823 OMIM ID: 607436
Drug and gene relationship at DGIdb

 

Expression of PAPOLB:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PAPOLB 56903 208271_at -0.0609 0.7908
GSE20347 PAPOLB 56903 208271_at -0.0518 0.3097
GSE23400 PAPOLB 56903 208271_at -0.0709 0.0038
GSE26886 PAPOLB 56903 242158_at -0.0106 0.9160
GSE29001 PAPOLB 56903 208271_at -0.1272 0.3068
GSE38129 PAPOLB 56903 208271_at -0.0501 0.2475
GSE45670 PAPOLB 56903 208271_at -0.0504 0.5959
GSE53622 PAPOLB 56903 153962 -0.1494 0.1702
GSE53624 PAPOLB 56903 153962 -0.0807 0.2035
GSE63941 PAPOLB 56903 208271_at 0.2290 0.1165
GSE77861 PAPOLB 56903 208271_at -0.0122 0.9100
TCGA PAPOLB 56903 RNAseq 1.7611 0.1092

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by PAPOLB expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of PAPOLB:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PAPOLB 56903 14 1 15
GSE20123 PAPOLB 56903 14 1 15
GSE43470 PAPOLB 56903 6 1 36
GSE46452 PAPOLB 56903 13 1 45
GSE47630 PAPOLB 56903 9 1 30
GSE54993 PAPOLB 56903 0 6 64
GSE54994 PAPOLB 56903 21 2 30
GSE60625 PAPOLB 56903 0 0 11
GSE74703 PAPOLB 56903 6 0 30
GSE74704 PAPOLB 56903 9 0 11
TCGA PAPOLB 56903 56 5 35

Total number of gains: 148; Total number of losses: 18; Total Number of normals: 322.  


 

Somatic mutations of PAPOLB:

 

Generating mutation plots.

 

Highly correlated genes for PAPOLB:

 

Showing top 20/205 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PAPOLBGDF20.732476303
PAPOLBMATN10.704238303
PAPOLBFGF230.701764303
PAPOLBKCNQ1DN0.698189303
PAPOLBSLC5A50.685642303
PAPOLBKCNA40.684388303
PAPOLBGJD20.677362303
PAPOLBKCNJ60.66973303
PAPOLBCCDC70.666271303
PAPOLBMMP260.663046503
PAPOLBBIRC70.660439303
PAPOLBC4BPB0.659012303
PAPOLBEDA2R0.658679303
PAPOLBZNF7170.649843303
PAPOLBIL9R0.64829403
PAPOLBHCRT0.647529404
PAPOLBIFNA80.647018303
PAPOLBCST80.645076403
PAPOLBHHLA10.64408404
PAPOLBNKAIN10.644031303

For details and further investigation, click here