Full name: poly(A) polymerase beta | Alias Symbol: PAPT | ||
Type: protein-coding gene | Cytoband: 7p22.1 | ||
Entrez ID: 56903 | HGNC ID: HGNC:15970 | Ensembl Gene: ENSG00000218823 | OMIM ID: 607436 |
Drug and gene relationship at DGIdb |
Expression of PAPOLB:
Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
---|---|---|---|---|---|---|
GSE17351 | PAPOLB | 56903 | 208271_at | -0.0609 | 0.7908 | |
GSE20347 | PAPOLB | 56903 | 208271_at | -0.0518 | 0.3097 | |
GSE23400 | PAPOLB | 56903 | 208271_at | -0.0709 | 0.0038 | |
GSE26886 | PAPOLB | 56903 | 242158_at | -0.0106 | 0.9160 | |
GSE29001 | PAPOLB | 56903 | 208271_at | -0.1272 | 0.3068 | |
GSE38129 | PAPOLB | 56903 | 208271_at | -0.0501 | 0.2475 | |
GSE45670 | PAPOLB | 56903 | 208271_at | -0.0504 | 0.5959 | |
GSE53622 | PAPOLB | 56903 | 153962 | -0.1494 | 0.1702 | |
GSE53624 | PAPOLB | 56903 | 153962 | -0.0807 | 0.2035 | |
GSE63941 | PAPOLB | 56903 | 208271_at | 0.2290 | 0.1165 | |
GSE77861 | PAPOLB | 56903 | 208271_at | -0.0122 | 0.9100 | |
TCGA | PAPOLB | 56903 | RNAseq | 1.7611 | 0.1092 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PAPOLB expression:
Note: Click image to view full size file.
Copy number change of PAPOLB:
Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
---|---|---|---|---|---|---|
GSE15526 | PAPOLB | 56903 | 14 | 1 | 15 | |
GSE20123 | PAPOLB | 56903 | 14 | 1 | 15 | |
GSE43470 | PAPOLB | 56903 | 6 | 1 | 36 | |
GSE46452 | PAPOLB | 56903 | 13 | 1 | 45 | |
GSE47630 | PAPOLB | 56903 | 9 | 1 | 30 | |
GSE54993 | PAPOLB | 56903 | 0 | 6 | 64 | |
GSE54994 | PAPOLB | 56903 | 21 | 2 | 30 | |
GSE60625 | PAPOLB | 56903 | 0 | 0 | 11 | |
GSE74703 | PAPOLB | 56903 | 6 | 0 | 30 | |
GSE74704 | PAPOLB | 56903 | 9 | 0 | 11 | |
TCGA | PAPOLB | 56903 | 56 | 5 | 35 |
Total number of gains: 148; Total number of losses: 18; Total Number of normals: 322.
Somatic mutations of PAPOLB:
Generating mutation plots.
Highly correlated genes for PAPOLB:
Showing top 20/205 corelated genes with mean PCC>0.5.
Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
---|---|---|---|---|---|
PAPOLB | GDF2 | 0.732476 | 3 | 0 | 3 |
PAPOLB | MATN1 | 0.704238 | 3 | 0 | 3 |
PAPOLB | FGF23 | 0.701764 | 3 | 0 | 3 |
PAPOLB | KCNQ1DN | 0.698189 | 3 | 0 | 3 |
PAPOLB | SLC5A5 | 0.685642 | 3 | 0 | 3 |
PAPOLB | KCNA4 | 0.684388 | 3 | 0 | 3 |
PAPOLB | GJD2 | 0.677362 | 3 | 0 | 3 |
PAPOLB | KCNJ6 | 0.66973 | 3 | 0 | 3 |
PAPOLB | CCDC7 | 0.666271 | 3 | 0 | 3 |
PAPOLB | MMP26 | 0.663046 | 5 | 0 | 3 |
PAPOLB | BIRC7 | 0.660439 | 3 | 0 | 3 |
PAPOLB | C4BPB | 0.659012 | 3 | 0 | 3 |
PAPOLB | EDA2R | 0.658679 | 3 | 0 | 3 |
PAPOLB | ZNF717 | 0.649843 | 3 | 0 | 3 |
PAPOLB | IL9R | 0.64829 | 4 | 0 | 3 |
PAPOLB | HCRT | 0.647529 | 4 | 0 | 4 |
PAPOLB | IFNA8 | 0.647018 | 3 | 0 | 3 |
PAPOLB | CST8 | 0.645076 | 4 | 0 | 3 |
PAPOLB | HHLA1 | 0.64408 | 4 | 0 | 4 |
PAPOLB | NKAIN1 | 0.644031 | 3 | 0 | 3 |
For details and further investigation, click here