KCNJ10

 

Full name: potassium inwardly rectifying channel subfamily J member 10 Alias Symbol: Kir4.1|Kir1.2
Type: protein-coding gene Cytoband: 1q23.2
Entrez ID: 3766 HGNC ID: HGNC:6256 Ensembl Gene: ENSG00000177807 OMIM ID: 602208
Drug and gene relationship at DGIdb

 

KCNJ10 involved pathways:

KEGG pathway Description View
hsa04971Gastric acid secretion

 

Expression of KCNJ10:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 KCNJ10 3766 228581_at -0.0828 0.7114
GSE20347 KCNJ10 3766 206692_at 0.0450 0.5353
GSE23400 KCNJ10 3766 206692_at -0.1115 0.0414
GSE26886 KCNJ10 3766 228581_at 0.1093 0.2300
GSE29001 KCNJ10 3766 206692_at -0.1350 0.5712
GSE38129 KCNJ10 3766 206692_at -0.0111 0.8950
GSE45670 KCNJ10 3766 228581_at 0.0040 0.9698
GSE53622 KCNJ10 3766 82380 0.4435 0.0214
GSE53624 KCNJ10 3766 82380 0.3795 0.0506
GSE63941 KCNJ10 3766 228581_at 0.0135 0.9510
GSE77861 KCNJ10 3766 228581_at -0.0510 0.6643
GSE97050 KCNJ10 3766 A_24_P387875 -0.6376 0.2616
SRP133303 KCNJ10 3766 RNAseq 0.0794 0.7578
SRP159526 KCNJ10 3766 RNAseq 0.2843 0.6593
SRP193095 KCNJ10 3766 RNAseq -0.1300 0.4432
SRP219564 KCNJ10 3766 RNAseq 0.3787 0.4760
TCGA KCNJ10 3766 RNAseq -1.6046 0.0000

Upregulated datasets: 0; Downregulated datasets: 1.  

 

Survival by KCNJ10 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of KCNJ10:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 KCNJ10 3766 10 0 20
GSE20123 KCNJ10 3766 10 0 20
GSE43470 KCNJ10 3766 7 2 34
GSE46452 KCNJ10 3766 2 1 56
GSE47630 KCNJ10 3766 15 0 25
GSE54993 KCNJ10 3766 0 5 65
GSE54994 KCNJ10 3766 16 0 37
GSE60625 KCNJ10 3766 0 0 11
GSE74703 KCNJ10 3766 7 2 27
GSE74704 KCNJ10 3766 4 0 16
TCGA KCNJ10 3766 44 3 49

Total number of gains: 115; Total number of losses: 13; Total Number of normals: 360.  

 

Somatic mutations of KCNJ10:

 

Generating mutation plots.

 

Highly correlated genes for KCNJ10:

 

Showing top 20/760 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
KCNJ10IFNA170.802023404
KCNJ10FOXN3-AS20.784404404
KCNJ10CRHR20.746492404
KCNJ10SLC17A40.742543404
KCNJ10ATG100.738957605
KCNJ10RFPL30.737967404
KCNJ10OR12D20.73761404
KCNJ10GABRB20.736472404
KCNJ10TCP10L0.734699404
KCNJ10GAD20.727662404
KCNJ10CHST40.719738404
KCNJ10GALNT80.714726404
KCNJ10KHDRBS20.709521505
KCNJ10OPHN10.709209404
KCNJ10RORB0.708435303
KCNJ10KIR2DS10.70707404
KCNJ10RSPH6A0.706311505
KCNJ10COLEC100.706105404
KCNJ10WNT60.704057303
KCNJ10ZNF4600.703612606

For details and further investigation, click here