| Full name: killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 2 | Alias Symbol: cl-43|nkat6|CD158B1|CD158k | ||
| Type: protein-coding gene | Cytoband: 19q13.4 alternate reference locus | ||
| Entrez ID: 3803 | HGNC ID: HGNC:6330 | Ensembl Gene: | OMIM ID: 604937 |
| Drug and gene relationship at DGIdb | |||
KIR2DL2 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04612 | Antigen processing and presentation | |
| hsa04650 | Natural killer cell mediated cytotoxicity |
Expression of KIR2DL2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KIR2DL2 | 3803 | 211397_x_at | 0.1761 | 0.5708 | |
| GSE20347 | KIR2DL2 | 3803 | 211397_x_at | 0.1424 | 0.1750 | |
| GSE23400 | KIR2DL2 | 3803 | 211397_x_at | -0.0423 | 0.3507 | |
| GSE26886 | KIR2DL2 | 3803 | 211397_x_at | 0.0225 | 0.8732 | |
| GSE29001 | KIR2DL2 | 3803 | 211397_x_at | 0.0079 | 0.9691 | |
| GSE38129 | KIR2DL2 | 3803 | 211397_x_at | -0.0170 | 0.8941 | |
| GSE45670 | KIR2DL2 | 3803 | 211397_x_at | 0.2023 | 0.0463 | |
| GSE63941 | KIR2DL2 | 3803 | 211397_x_at | 0.2156 | 0.2542 | |
| GSE77861 | KIR2DL2 | 3803 | 211397_x_at | -0.0425 | 0.8037 | |
| GSE97050 | KIR2DL2 | 3803 | A_33_P3313920 | -0.4533 | 0.6553 |
Upregulated datasets: 0; Downregulated datasets: 0.
Copy number change of KIR2DL2:
No record found for this gene.
Somatic mutations of KIR2DL2:
Generating mutation plots.
Highly correlated genes for KIR2DL2:
Showing top 20/824 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KIR2DL2 | GAD2 | 0.742809 | 4 | 0 | 4 |
| KIR2DL2 | KHDRBS2 | 0.737336 | 4 | 0 | 4 |
| KIR2DL2 | INE1 | 0.731585 | 4 | 0 | 4 |
| KIR2DL2 | OR10H3 | 0.727268 | 5 | 0 | 5 |
| KIR2DL2 | IFNA7 | 0.722105 | 5 | 0 | 5 |
| KIR2DL2 | WRNIP1 | 0.717978 | 4 | 0 | 4 |
| KIR2DL2 | TNFSF8 | 0.715415 | 4 | 0 | 4 |
| KIR2DL2 | CRHBP | 0.705526 | 5 | 0 | 5 |
| KIR2DL2 | KIR2DL1 | 0.698713 | 7 | 0 | 6 |
| KIR2DL2 | INSL5 | 0.695722 | 4 | 0 | 4 |
| KIR2DL2 | OPHN1 | 0.690588 | 4 | 0 | 4 |
| KIR2DL2 | BPIFA1 | 0.688961 | 5 | 0 | 4 |
| KIR2DL2 | ANO3 | 0.685364 | 3 | 0 | 3 |
| KIR2DL2 | LINC00652 | 0.684328 | 3 | 0 | 3 |
| KIR2DL2 | TPD52L3 | 0.683875 | 3 | 0 | 3 |
| KIR2DL2 | LUZP4 | 0.683433 | 6 | 0 | 6 |
| KIR2DL2 | CLCA1 | 0.682599 | 4 | 0 | 4 |
| KIR2DL2 | CRP | 0.681687 | 4 | 0 | 4 |
| KIR2DL2 | DTX1 | 0.680431 | 3 | 0 | 3 |
| KIR2DL2 | LINC00474 | 0.679333 | 4 | 0 | 4 |
For details and further investigation, click here
