NXPE4

 

Full name: neurexophilin and PC-esterase domain family member 4 Alias Symbol: FLJ20127
Type: protein-coding gene Cytoband: 11q23.2
Entrez ID: 54827 HGNC ID: HGNC:23117 Ensembl Gene: ENSG00000137634 OMIM ID: 618133

 

Expression of NXPE4:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 NXPE4 54827 220645_at -0.0971 0.7886
GSE20347 NXPE4 54827 220645_at 0.0909 0.3672
GSE23400 NXPE4 54827 220645_at -0.0904 0.0096
GSE26886 NXPE4 54827 220645_at -0.1869 0.1037
GSE29001 NXPE4 54827 220645_at -0.0679 0.7261
GSE38129 NXPE4 54827 220645_at -0.0959 0.3636
GSE45670 NXPE4 54827 220645_at -0.3785 0.0095
GSE53622 NXPE4 54827 6950 -1.9008 0.0000
GSE53624 NXPE4 54827 6950 -2.2778 0.0000
GSE63941 NXPE4 54827 220645_at 0.3499 0.0201
GSE77861 NXPE4 54827 220645_at -0.0269 0.8542
SRP133303 NXPE4 54827 RNAseq -2.7329 0.0000

Upregulated datasets: 0; Downregulated datasets: 3.  


 

Survival by NXPE4 expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  


Copy number change of NXPE4:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 NXPE4 54827 0 13 17
GSE20123 NXPE4 54827 0 13 17
GSE43470 NXPE4 54827 2 7 34
GSE46452 NXPE4 54827 3 26 30
GSE47630 NXPE4 54827 2 19 19
GSE54993 NXPE4 54827 10 0 60
GSE54994 NXPE4 54827 5 19 29
GSE60625 NXPE4 54827 0 3 8
GSE74703 NXPE4 54827 1 5 30
GSE74704 NXPE4 54827 0 9 11
TCGA NXPE4 54827 6 49 41

Total number of gains: 29; Total number of losses: 163; Total Number of normals: 296.  


 

Somatic mutations of NXPE4:

 

Generating mutation plots.

 

Highly correlated genes for NXPE4:

 

Showing top 20/665 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
NXPE4KIR3DL30.786288505
NXPE4GLYATL20.764599404
NXPE4TSPAN80.756383404
NXPE4BPIFB20.755673505
NXPE4KRT760.753357404
NXPE4PRR340.751051403
NXPE4CHRM10.744052404
NXPE4SLC28A20.739914404
NXPE4GP20.737688908
NXPE4BPIFB10.735923404
NXPE4ENGASE0.733895303
NXPE4TNR0.730471505
NXPE4MAS10.729775505
NXPE4CHRM50.72829505
NXPE4MC2R0.727645605
NXPE4BCAN0.726167505
NXPE4ZG16B0.724486404
NXPE4GJB40.724112505
NXPE4SCGB3A10.721986404
NXPE4SLC5A70.720475505

For details and further investigation, click here