| Full name: aquaporin 10 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1q21.3 | ||
| Entrez ID: 89872 | HGNC ID: HGNC:16029 | Ensembl Gene: ENSG00000143595 | OMIM ID: 606578 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of AQP10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AQP10 | 89872 | 1555338_s_at | 0.2339 | 0.5231 | |
| GSE26886 | AQP10 | 89872 | 1555338_s_at | 0.1898 | 0.1368 | |
| GSE45670 | AQP10 | 89872 | 1555338_s_at | 0.1445 | 0.0771 | |
| GSE53622 | AQP10 | 89872 | 25451 | 0.6217 | 0.0000 | |
| GSE53624 | AQP10 | 89872 | 25451 | 0.9372 | 0.0000 | |
| GSE63941 | AQP10 | 89872 | 1555338_s_at | 0.2275 | 0.0904 | |
| GSE77861 | AQP10 | 89872 | 1555338_s_at | -0.0230 | 0.7894 | |
| GSE97050 | AQP10 | 89872 | A_23_P126613 | 0.0600 | 0.7856 | |
| TCGA | AQP10 | 89872 | RNAseq | 0.3923 | 0.5668 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by AQP10 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AQP10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AQP10 | 89872 | 14 | 0 | 16 | |
| GSE20123 | AQP10 | 89872 | 14 | 0 | 16 | |
| GSE43470 | AQP10 | 89872 | 6 | 2 | 35 | |
| GSE46452 | AQP10 | 89872 | 2 | 1 | 56 | |
| GSE47630 | AQP10 | 89872 | 14 | 0 | 26 | |
| GSE54993 | AQP10 | 89872 | 0 | 4 | 66 | |
| GSE54994 | AQP10 | 89872 | 16 | 0 | 37 | |
| GSE60625 | AQP10 | 89872 | 0 | 0 | 11 | |
| GSE74703 | AQP10 | 89872 | 6 | 1 | 29 | |
| GSE74704 | AQP10 | 89872 | 7 | 0 | 13 | |
| TCGA | AQP10 | 89872 | 38 | 2 | 56 |
Total number of gains: 117; Total number of losses: 10; Total Number of normals: 361.
Somatic mutations of AQP10:
Generating mutation plots.
Highly correlated genes for AQP10:
Showing top 20/62 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AQP10 | TNFSF11 | 0.757143 | 3 | 0 | 3 |
| AQP10 | MYOD1 | 0.725748 | 3 | 0 | 3 |
| AQP10 | FAM71A | 0.725126 | 3 | 0 | 3 |
| AQP10 | ATP2B3 | 0.718824 | 3 | 0 | 3 |
| AQP10 | ST8SIA3 | 0.708966 | 3 | 0 | 3 |
| AQP10 | CYP26A1 | 0.707229 | 3 | 0 | 3 |
| AQP10 | KRBA2 | 0.688143 | 3 | 0 | 3 |
| AQP10 | HPX | 0.686216 | 4 | 0 | 4 |
| AQP10 | CALCR | 0.673367 | 3 | 0 | 3 |
| AQP10 | TRIM36 | 0.662422 | 3 | 0 | 3 |
| AQP10 | STAC2 | 0.660276 | 4 | 0 | 3 |
| AQP10 | HTR6 | 0.658785 | 3 | 0 | 3 |
| AQP10 | NPW | 0.655925 | 3 | 0 | 3 |
| AQP10 | TTBK1 | 0.65136 | 4 | 0 | 3 |
| AQP10 | TCP10 | 0.650051 | 3 | 0 | 3 |
| AQP10 | C2orf81 | 0.646032 | 4 | 0 | 4 |
| AQP10 | CEMP1 | 0.639162 | 3 | 0 | 3 |
| AQP10 | AMHR2 | 0.638015 | 4 | 0 | 4 |
| AQP10 | CCR3 | 0.63676 | 3 | 0 | 3 |
| AQP10 | PLA2G4D | 0.629355 | 3 | 0 | 3 |
For details and further investigation, click here
