| Full name: dihydropyrimidinase like 5 | Alias Symbol: CRMP5|Ulip6|CRMP-5|CRAM | ||
| Type: protein-coding gene | Cytoband: 2p23.3 | ||
| Entrez ID: 56896 | HGNC ID: HGNC:20637 | Ensembl Gene: ENSG00000157851 | OMIM ID: 608383 |
| Drug and gene relationship at DGIdb | |||
DPYSL5 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04360 | Axon guidance |
Expression of DPYSL5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DPYSL5 | 56896 | 224100_s_at | -0.0113 | 0.9687 | |
| GSE26886 | DPYSL5 | 56896 | 224100_s_at | 0.2736 | 0.0457 | |
| GSE45670 | DPYSL5 | 56896 | 224100_s_at | 0.0287 | 0.7850 | |
| GSE53622 | DPYSL5 | 56896 | 107537 | 0.3256 | 0.0406 | |
| GSE53624 | DPYSL5 | 56896 | 107537 | 0.5566 | 0.0000 | |
| GSE63941 | DPYSL5 | 56896 | 222797_at | 0.4685 | 0.3128 | |
| GSE77861 | DPYSL5 | 56896 | 224100_s_at | -0.1305 | 0.2155 | |
| SRP133303 | DPYSL5 | 56896 | RNAseq | 1.2872 | 0.0163 | |
| TCGA | DPYSL5 | 56896 | RNAseq | -0.0919 | 0.9012 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by DPYSL5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DPYSL5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DPYSL5 | 56896 | 11 | 2 | 17 | |
| GSE20123 | DPYSL5 | 56896 | 11 | 2 | 17 | |
| GSE43470 | DPYSL5 | 56896 | 3 | 1 | 39 | |
| GSE46452 | DPYSL5 | 56896 | 3 | 4 | 52 | |
| GSE47630 | DPYSL5 | 56896 | 8 | 0 | 32 | |
| GSE54993 | DPYSL5 | 56896 | 0 | 6 | 64 | |
| GSE54994 | DPYSL5 | 56896 | 10 | 0 | 43 | |
| GSE60625 | DPYSL5 | 56896 | 0 | 3 | 8 | |
| GSE74703 | DPYSL5 | 56896 | 3 | 0 | 33 | |
| GSE74704 | DPYSL5 | 56896 | 9 | 1 | 10 | |
| TCGA | DPYSL5 | 56896 | 37 | 2 | 57 |
Total number of gains: 95; Total number of losses: 21; Total Number of normals: 372.
Somatic mutations of DPYSL5:
Generating mutation plots.
Highly correlated genes for DPYSL5:
Showing top 20/75 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DPYSL5 | GLRA2 | 0.741366 | 3 | 0 | 3 |
| DPYSL5 | ASB12 | 0.705985 | 3 | 0 | 3 |
| DPYSL5 | ABHD1 | 0.689043 | 3 | 0 | 3 |
| DPYSL5 | CC2D2B | 0.687791 | 3 | 0 | 3 |
| DPYSL5 | GATA3-AS1 | 0.685675 | 3 | 0 | 3 |
| DPYSL5 | GSX1 | 0.685548 | 3 | 0 | 3 |
| DPYSL5 | NR4A3 | 0.677968 | 3 | 0 | 3 |
| DPYSL5 | CHGA | 0.676331 | 3 | 0 | 3 |
| DPYSL5 | HOTTIP | 0.662759 | 3 | 0 | 3 |
| DPYSL5 | ROPN1L | 0.655877 | 4 | 0 | 3 |
| DPYSL5 | PYY | 0.654151 | 3 | 0 | 3 |
| DPYSL5 | TCL6 | 0.651859 | 3 | 0 | 3 |
| DPYSL5 | MC2R | 0.647425 | 3 | 0 | 3 |
| DPYSL5 | THEG | 0.642214 | 3 | 0 | 3 |
| DPYSL5 | MUC3B | 0.640108 | 4 | 0 | 3 |
| DPYSL5 | CCDC151 | 0.632906 | 4 | 0 | 3 |
| DPYSL5 | OR10A3 | 0.632793 | 3 | 0 | 3 |
| DPYSL5 | RNF157 | 0.628762 | 4 | 0 | 4 |
| DPYSL5 | OR8D2 | 0.625875 | 3 | 0 | 3 |
| DPYSL5 | AKR1E2 | 0.625726 | 3 | 0 | 3 |
For details and further investigation, click here
