| Full name: uromodulin | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 16p12.3 | ||
| Entrez ID: 7369 | HGNC ID: HGNC:12559 | Ensembl Gene: ENSG00000169344 | OMIM ID: 191845 |
| Drug and gene relationship at DGIdb | |||
Expression of UMOD:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UMOD | 7369 | 206716_at | -0.1101 | 0.7154 | |
| GSE20347 | UMOD | 7369 | 206716_at | -0.1376 | 0.1570 | |
| GSE23400 | UMOD | 7369 | 206716_at | -0.3215 | 0.0000 | |
| GSE26886 | UMOD | 7369 | 206716_at | -0.1388 | 0.2006 | |
| GSE29001 | UMOD | 7369 | 206716_at | -0.2883 | 0.0637 | |
| GSE38129 | UMOD | 7369 | 206716_at | -0.2504 | 0.0134 | |
| GSE45670 | UMOD | 7369 | 206716_at | -0.0694 | 0.5701 | |
| GSE63941 | UMOD | 7369 | 206716_at | 0.2618 | 0.0888 | |
| GSE77861 | UMOD | 7369 | 206716_at | -0.1015 | 0.3784 | |
| TCGA | UMOD | 7369 | RNAseq | -4.0067 | 0.0239 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by UMOD expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of UMOD:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UMOD | 7369 | 6 | 3 | 21 | |
| GSE20123 | UMOD | 7369 | 6 | 2 | 22 | |
| GSE43470 | UMOD | 7369 | 3 | 3 | 37 | |
| GSE46452 | UMOD | 7369 | 38 | 1 | 20 | |
| GSE47630 | UMOD | 7369 | 11 | 6 | 23 | |
| GSE54993 | UMOD | 7369 | 3 | 5 | 62 | |
| GSE54994 | UMOD | 7369 | 3 | 10 | 40 | |
| GSE60625 | UMOD | 7369 | 4 | 0 | 7 | |
| GSE74703 | UMOD | 7369 | 3 | 2 | 31 | |
| GSE74704 | UMOD | 7369 | 3 | 1 | 16 | |
| TCGA | UMOD | 7369 | 19 | 13 | 64 |
Total number of gains: 99; Total number of losses: 46; Total Number of normals: 343.
Somatic mutations of UMOD:
Generating mutation plots.
Highly correlated genes for UMOD:
Showing top 20/1133 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UMOD | LRTM1 | 0.774696 | 4 | 0 | 4 |
| UMOD | INO80D | 0.759367 | 4 | 0 | 4 |
| UMOD | SCNN1G | 0.757601 | 4 | 0 | 4 |
| UMOD | PRG3 | 0.742899 | 4 | 0 | 4 |
| UMOD | MYT1 | 0.739033 | 4 | 0 | 4 |
| UMOD | SLC5A7 | 0.738934 | 4 | 0 | 4 |
| UMOD | ZNF717 | 0.727826 | 4 | 0 | 4 |
| UMOD | APBA1 | 0.727141 | 5 | 0 | 5 |
| UMOD | PF4 | 0.726003 | 5 | 0 | 5 |
| UMOD | P2RX6 | 0.722986 | 5 | 0 | 5 |
| UMOD | MC5R | 0.721661 | 4 | 0 | 4 |
| UMOD | RNF17 | 0.720419 | 4 | 0 | 4 |
| UMOD | PSG9 | 0.717658 | 3 | 0 | 3 |
| UMOD | EPB42 | 0.717468 | 5 | 0 | 5 |
| UMOD | ACTL6B | 0.717025 | 4 | 0 | 4 |
| UMOD | UBQLN3 | 0.716387 | 5 | 0 | 5 |
| UMOD | KSR1 | 0.713145 | 4 | 0 | 4 |
| UMOD | HRH2 | 0.706614 | 4 | 0 | 4 |
| UMOD | GLRA2 | 0.705751 | 3 | 0 | 3 |
| UMOD | EPS8L3 | 0.700674 | 4 | 0 | 3 |
For details and further investigation, click here
