GPR25

 

Full name: G protein-coupled receptor 25 Alias Symbol: 
Type: protein-coding gene Cytoband: 1q32.1
Entrez ID: 2848 HGNC ID: HGNC:4480 Ensembl Gene: ENSG00000170128 OMIM ID: 602174
Drug and gene relationship at DGIdb

 

Expression of GPR25:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 GPR25 2848 221363_x_at -0.1443 0.5496
GSE20347 GPR25 2848 221363_x_at -0.2183 0.0004
GSE23400 GPR25 2848 221363_x_at -0.1575 0.0000
GSE26886 GPR25 2848 221363_x_at 0.1163 0.3191
GSE29001 GPR25 2848 221363_x_at -0.2008 0.0151
GSE38129 GPR25 2848 221363_x_at -0.1777 0.0141
GSE45670 GPR25 2848 221363_x_at -0.1385 0.1953
GSE53622 GPR25 2848 58158 0.1991 0.0015
GSE53624 GPR25 2848 58158 0.2301 0.0016
GSE63941 GPR25 2848 221363_x_at 0.0872 0.4835
GSE77861 GPR25 2848 221363_x_at -0.2986 0.1086
GSE97050 GPR25 2848 A_23_P316531 0.0061 0.9870
TCGA GPR25 2848 RNAseq -0.2647 0.5937

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by GPR25 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of GPR25:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 GPR25 2848 11 0 19
GSE20123 GPR25 2848 11 0 19
GSE43470 GPR25 2848 6 0 37
GSE46452 GPR25 2848 3 1 55
GSE47630 GPR25 2848 14 0 26
GSE54993 GPR25 2848 0 6 64
GSE54994 GPR25 2848 15 0 38
GSE60625 GPR25 2848 0 0 11
GSE74703 GPR25 2848 6 0 30
GSE74704 GPR25 2848 5 0 15
TCGA GPR25 2848 43 4 49

Total number of gains: 114; Total number of losses: 11; Total Number of normals: 363.  


 

Somatic mutations of GPR25:

 

Generating mutation plots.

 

Highly correlated genes for GPR25:

 

Showing top 20/626 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
GPR25C2CD4D0.806498303
GPR25C1QL20.803869303
GPR25STRC0.802735303
GPR25KCNH30.792507303
GPR25MRGPRG0.792061303
GPR25NTNG20.778025303
GPR25NKX6-30.774716404
GPR25C9orf1530.773003303
GPR25DCDC10.764372303
GPR25RBM430.761851404
GPR25PLA2G2C0.758092303
GPR25LBX20.756277303
GPR25CXorf380.750413303
GPR25POM121L120.747907303
GPR25HBM0.746371404
GPR25LHB0.738766303
GPR25OR52L10.738319303
GPR25GLI40.734535303
GPR25YY20.731493303
GPR25BSX0.731198303

For details and further investigation, click here