| Full name: hemoglobin subunit mu | Alias Symbol: HBK | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 3042 | HGNC ID: HGNC:4826 | Ensembl Gene: ENSG00000206177 | OMIM ID: 609639 |
| Drug and gene relationship at DGIdb | |||
Expression of HBM:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HBM | 3042 | 240336_at | -0.1700 | 0.6008 | |
| GSE26886 | HBM | 3042 | 240336_at | 0.0829 | 0.4655 | |
| GSE45670 | HBM | 3042 | 240336_at | -0.0262 | 0.8104 | |
| GSE53622 | HBM | 3042 | 34886 | 0.2263 | 0.0000 | |
| GSE53624 | HBM | 3042 | 34886 | 0.1813 | 0.0086 | |
| GSE63941 | HBM | 3042 | 240336_at | 0.2577 | 0.1310 | |
| GSE77861 | HBM | 3042 | 240336_at | -0.1425 | 0.1728 | |
| GSE97050 | HBM | 3042 | A_33_P3326235 | -0.4013 | 0.1581 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HBM expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HBM:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HBM | 3042 | 5 | 5 | 20 | |
| GSE20123 | HBM | 3042 | 5 | 4 | 21 | |
| GSE43470 | HBM | 3042 | 3 | 7 | 33 | |
| GSE46452 | HBM | 3042 | 38 | 1 | 20 | |
| GSE47630 | HBM | 3042 | 13 | 6 | 21 | |
| GSE54993 | HBM | 3042 | 3 | 5 | 62 | |
| GSE54994 | HBM | 3042 | 4 | 10 | 39 | |
| GSE60625 | HBM | 3042 | 4 | 0 | 7 | |
| GSE74703 | HBM | 3042 | 3 | 5 | 28 | |
| GSE74704 | HBM | 3042 | 3 | 2 | 15 | |
| TCGA | HBM | 3042 | 20 | 15 | 61 |
Total number of gains: 101; Total number of losses: 60; Total Number of normals: 327.
Somatic mutations of HBM:
Generating mutation plots.
Highly correlated genes for HBM:
Showing top 20/356 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HBM | CTSE | 0.758969 | 3 | 0 | 3 |
| HBM | BLACE | 0.754248 | 3 | 0 | 3 |
| HBM | GPR25 | 0.746371 | 4 | 0 | 4 |
| HBM | C1orf61 | 0.744478 | 3 | 0 | 3 |
| HBM | C1QL2 | 0.733863 | 3 | 0 | 3 |
| HBM | ADH6 | 0.7303 | 3 | 0 | 3 |
| HBM | OR2A5 | 0.730128 | 3 | 0 | 3 |
| HBM | PSMB11 | 0.729459 | 3 | 0 | 3 |
| HBM | AGER | 0.72718 | 3 | 0 | 3 |
| HBM | SLC6A13 | 0.725077 | 3 | 0 | 3 |
| HBM | DCDC1 | 0.72434 | 3 | 0 | 3 |
| HBM | PHF7 | 0.719193 | 3 | 0 | 3 |
| HBM | GPR150 | 0.703729 | 3 | 0 | 3 |
| HBM | LCN8 | 0.702429 | 4 | 0 | 3 |
| HBM | FSCN2 | 0.695643 | 4 | 0 | 4 |
| HBM | ZNF205 | 0.69532 | 3 | 0 | 3 |
| HBM | CCDC33 | 0.693972 | 4 | 0 | 3 |
| HBM | DUOXA2 | 0.690136 | 4 | 0 | 3 |
| HBM | OR2T1 | 0.690078 | 3 | 0 | 3 |
| HBM | ATP4A | 0.687021 | 3 | 0 | 3 |
For details and further investigation, click here
