| Full name: G protein-coupled receptor 35 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2q37.3 | ||
| Entrez ID: 2859 | HGNC ID: HGNC:4492 | Ensembl Gene: ENSG00000178623 | OMIM ID: 602646 |
| Drug and gene relationship at DGIdb | |||
Expression of GPR35:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GPR35 | 2859 | 210264_at | 0.0649 | 0.8749 | |
| GSE20347 | GPR35 | 2859 | 210264_at | -0.1556 | 0.0561 | |
| GSE23400 | GPR35 | 2859 | 210264_at | -0.1878 | 0.0002 | |
| GSE26886 | GPR35 | 2859 | 210264_at | -0.0980 | 0.5835 | |
| GSE29001 | GPR35 | 2859 | 210264_at | -0.0751 | 0.5893 | |
| GSE38129 | GPR35 | 2859 | 210264_at | -0.2633 | 0.0009 | |
| GSE45670 | GPR35 | 2859 | 210264_at | 0.0693 | 0.4774 | |
| GSE53622 | GPR35 | 2859 | 17728 | 0.4053 | 0.0001 | |
| GSE53624 | GPR35 | 2859 | 17728 | -0.2973 | 0.0038 | |
| GSE63941 | GPR35 | 2859 | 210264_at | 0.0713 | 0.8033 | |
| GSE77861 | GPR35 | 2859 | 210264_at | -0.0093 | 0.9364 | |
| GSE97050 | GPR35 | 2859 | A_33_P3375368 | 0.1494 | 0.4762 | |
| SRP007169 | GPR35 | 2859 | RNAseq | -1.9950 | 0.0080 | |
| SRP064894 | GPR35 | 2859 | RNAseq | -0.0581 | 0.8424 | |
| SRP133303 | GPR35 | 2859 | RNAseq | -0.3680 | 0.1089 | |
| SRP159526 | GPR35 | 2859 | RNAseq | 0.1369 | 0.8304 | |
| SRP193095 | GPR35 | 2859 | RNAseq | -0.7543 | 0.1246 | |
| SRP219564 | GPR35 | 2859 | RNAseq | -0.0962 | 0.7741 | |
| TCGA | GPR35 | 2859 | RNAseq | -1.2429 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by GPR35 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GPR35:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GPR35 | 2859 | 1 | 12 | 17 | |
| GSE20123 | GPR35 | 2859 | 1 | 12 | 17 | |
| GSE43470 | GPR35 | 2859 | 1 | 9 | 33 | |
| GSE46452 | GPR35 | 2859 | 0 | 5 | 54 | |
| GSE47630 | GPR35 | 2859 | 4 | 5 | 31 | |
| GSE54993 | GPR35 | 2859 | 3 | 3 | 64 | |
| GSE54994 | GPR35 | 2859 | 8 | 9 | 36 | |
| GSE60625 | GPR35 | 2859 | 0 | 3 | 8 | |
| GSE74703 | GPR35 | 2859 | 1 | 7 | 28 | |
| GSE74704 | GPR35 | 2859 | 1 | 5 | 14 | |
| TCGA | GPR35 | 2859 | 11 | 29 | 56 |
Total number of gains: 31; Total number of losses: 99; Total Number of normals: 358.
Somatic mutations of GPR35:
Generating mutation plots.
Highly correlated genes for GPR35:
Showing top 20/636 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GPR35 | RIMBP2 | 0.798533 | 3 | 0 | 3 |
| GPR35 | STRC | 0.770019 | 3 | 0 | 3 |
| GPR35 | ABCC2 | 0.768317 | 3 | 0 | 3 |
| GPR35 | DEFB108B | 0.754251 | 3 | 0 | 3 |
| GPR35 | MAGEA8 | 0.716756 | 4 | 0 | 4 |
| GPR35 | GPR152 | 0.707068 | 3 | 0 | 3 |
| GPR35 | COL4A3 | 0.706138 | 4 | 0 | 4 |
| GPR35 | FNDC9 | 0.704819 | 3 | 0 | 3 |
| GPR35 | KRTAP9-1 | 0.703317 | 3 | 0 | 3 |
| GPR35 | PANX2 | 0.701242 | 5 | 0 | 5 |
| GPR35 | OR4D6 | 0.694671 | 3 | 0 | 3 |
| GPR35 | NTNG2 | 0.693281 | 3 | 0 | 3 |
| GPR35 | CSH2 | 0.689241 | 3 | 0 | 3 |
| GPR35 | FBRSL1 | 0.682017 | 3 | 0 | 3 |
| GPR35 | ZNF527 | 0.679946 | 4 | 0 | 3 |
| GPR35 | GRIK4 | 0.676406 | 4 | 0 | 4 |
| GPR35 | CAPN13 | 0.676144 | 3 | 0 | 3 |
| GPR35 | FBLL1 | 0.675717 | 3 | 0 | 3 |
| GPR35 | FAM120C | 0.675032 | 3 | 0 | 3 |
| GPR35 | ARSA | 0.67431 | 4 | 0 | 3 |
For details and further investigation, click here
