| Full name: calpain 13 | Alias Symbol: FLJ23523 | ||
| Type: protein-coding gene | Cytoband: 2p23.1 | ||
| Entrez ID: 92291 | HGNC ID: HGNC:16663 | Ensembl Gene: ENSG00000162949 | OMIM ID: 610228 |
| Drug and gene relationship at DGIdb | |||
Expression of CAPN13:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CAPN13 | 92291 | 229499_at | 0.0298 | 0.9530 | |
| GSE26886 | CAPN13 | 92291 | 229499_at | 0.3087 | 0.4470 | |
| GSE45670 | CAPN13 | 92291 | 229499_at | 0.6167 | 0.0244 | |
| GSE53622 | CAPN13 | 92291 | 72135 | 0.3603 | 0.1516 | |
| GSE53624 | CAPN13 | 92291 | 42821 | -0.1510 | 0.3820 | |
| GSE63941 | CAPN13 | 92291 | 229499_at | 0.2889 | 0.3788 | |
| GSE77861 | CAPN13 | 92291 | 229499_at | -0.1582 | 0.0999 | |
| GSE97050 | CAPN13 | 92291 | A_23_P101972 | 0.6050 | 0.3751 | |
| SRP133303 | CAPN13 | 92291 | RNAseq | 2.0327 | 0.0064 | |
| SRP159526 | CAPN13 | 92291 | RNAseq | -0.9303 | 0.1670 | |
| TCGA | CAPN13 | 92291 | RNAseq | -1.4936 | 0.0343 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by CAPN13 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CAPN13:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CAPN13 | 92291 | 10 | 1 | 19 | |
| GSE20123 | CAPN13 | 92291 | 9 | 1 | 20 | |
| GSE43470 | CAPN13 | 92291 | 2 | 1 | 40 | |
| GSE46452 | CAPN13 | 92291 | 2 | 4 | 53 | |
| GSE47630 | CAPN13 | 92291 | 8 | 0 | 32 | |
| GSE54993 | CAPN13 | 92291 | 0 | 6 | 64 | |
| GSE54994 | CAPN13 | 92291 | 10 | 0 | 43 | |
| GSE60625 | CAPN13 | 92291 | 0 | 3 | 8 | |
| GSE74703 | CAPN13 | 92291 | 2 | 0 | 34 | |
| GSE74704 | CAPN13 | 92291 | 9 | 1 | 10 | |
| TCGA | CAPN13 | 92291 | 36 | 2 | 58 |
Total number of gains: 88; Total number of losses: 19; Total Number of normals: 381.
Somatic mutations of CAPN13:
Generating mutation plots.
Highly correlated genes for CAPN13:
Showing top 20/77 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CAPN13 | KLK4 | 0.770666 | 3 | 0 | 3 |
| CAPN13 | ATP6V0A4 | 0.725578 | 3 | 0 | 3 |
| CAPN13 | SEMA5B | 0.723665 | 4 | 0 | 4 |
| CAPN13 | BTBD8 | 0.713091 | 3 | 0 | 3 |
| CAPN13 | MBL2 | 0.710654 | 3 | 0 | 3 |
| CAPN13 | TRIL | 0.709905 | 3 | 0 | 3 |
| CAPN13 | GGTLC1 | 0.709165 | 3 | 0 | 3 |
| CAPN13 | ERBB2 | 0.706978 | 3 | 0 | 3 |
| CAPN13 | FGFR4 | 0.687705 | 3 | 0 | 3 |
| CAPN13 | DAPK2 | 0.681753 | 4 | 0 | 3 |
| CAPN13 | SLC22A31 | 0.678537 | 4 | 0 | 4 |
| CAPN13 | SIRT6 | 0.677729 | 3 | 0 | 3 |
| CAPN13 | GPR35 | 0.676144 | 3 | 0 | 3 |
| CAPN13 | PKLR | 0.674221 | 3 | 0 | 3 |
| CAPN13 | FAM186A | 0.670799 | 3 | 0 | 3 |
| CAPN13 | SYCE3 | 0.668396 | 3 | 0 | 3 |
| CAPN13 | IQCH | 0.667731 | 3 | 0 | 3 |
| CAPN13 | BANCR | 0.665276 | 3 | 0 | 3 |
| CAPN13 | PSTPIP1 | 0.656519 | 3 | 0 | 3 |
| CAPN13 | EYS | 0.654537 | 3 | 0 | 3 |
For details and further investigation, click here
