| Full name: RIMS binding protein 2 | Alias Symbol: KIAA0318|RBP2|MGC15831|RIM-BP2|PPP1R133 | ||
| Type: protein-coding gene | Cytoband: 12q24.33 | ||
| Entrez ID: 23504 | HGNC ID: HGNC:30339 | Ensembl Gene: ENSG00000060709 | OMIM ID: 611602 |
| Drug and gene relationship at DGIdb | |||
Expression of RIMBP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RIMBP2 | 23504 | 238817_at | 0.2426 | 0.4053 | |
| GSE20347 | RIMBP2 | 23504 | 214811_at | -0.0572 | 0.6602 | |
| GSE23400 | RIMBP2 | 23504 | 214811_at | -0.0314 | 0.6476 | |
| GSE26886 | RIMBP2 | 23504 | 238817_at | -0.0072 | 0.9575 | |
| GSE29001 | RIMBP2 | 23504 | 214811_at | -0.0964 | 0.7654 | |
| GSE38129 | RIMBP2 | 23504 | 214811_at | -0.1547 | 0.2160 | |
| GSE45670 | RIMBP2 | 23504 | 214811_at | 0.0222 | 0.9378 | |
| GSE53622 | RIMBP2 | 23504 | 138195 | 0.1432 | 0.1321 | |
| GSE53624 | RIMBP2 | 23504 | 138195 | -0.7347 | 0.0000 | |
| GSE77861 | RIMBP2 | 23504 | 214811_at | 0.0999 | 0.6337 | |
| GSE97050 | RIMBP2 | 23504 | A_32_P334325 | 0.3389 | 0.1855 | |
| SRP133303 | RIMBP2 | 23504 | RNAseq | 0.4767 | 0.2625 | |
| SRP159526 | RIMBP2 | 23504 | RNAseq | 0.8959 | 0.2586 | |
| SRP193095 | RIMBP2 | 23504 | RNAseq | 0.5017 | 0.1537 | |
| SRP219564 | RIMBP2 | 23504 | RNAseq | -0.7325 | 0.2143 | |
| TCGA | RIMBP2 | 23504 | RNAseq | -0.7740 | 0.0228 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RIMBP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RIMBP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RIMBP2 | 23504 | 4 | 4 | 22 | |
| GSE20123 | RIMBP2 | 23504 | 4 | 4 | 22 | |
| GSE43470 | RIMBP2 | 23504 | 2 | 2 | 39 | |
| GSE46452 | RIMBP2 | 23504 | 8 | 2 | 49 | |
| GSE47630 | RIMBP2 | 23504 | 9 | 3 | 28 | |
| GSE54993 | RIMBP2 | 23504 | 0 | 6 | 64 | |
| GSE54994 | RIMBP2 | 23504 | 4 | 7 | 42 | |
| GSE60625 | RIMBP2 | 23504 | 0 | 0 | 11 | |
| GSE74703 | RIMBP2 | 23504 | 2 | 1 | 33 | |
| GSE74704 | RIMBP2 | 23504 | 2 | 3 | 15 | |
| TCGA | RIMBP2 | 23504 | 21 | 15 | 60 |
Total number of gains: 56; Total number of losses: 47; Total Number of normals: 385.
Somatic mutations of RIMBP2:
Generating mutation plots.
Highly correlated genes for RIMBP2:
Showing top 20/172 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RIMBP2 | GPR35 | 0.798533 | 3 | 0 | 3 |
| RIMBP2 | GPR152 | 0.766265 | 3 | 0 | 3 |
| RIMBP2 | UTF1 | 0.76338 | 3 | 0 | 3 |
| RIMBP2 | CELF5 | 0.75718 | 3 | 0 | 3 |
| RIMBP2 | STRC | 0.720687 | 3 | 0 | 3 |
| RIMBP2 | IL1F10 | 0.710591 | 3 | 0 | 3 |
| RIMBP2 | KAT2A | 0.708695 | 3 | 0 | 3 |
| RIMBP2 | FAM120C | 0.706785 | 3 | 0 | 3 |
| RIMBP2 | SLC8A3 | 0.706113 | 3 | 0 | 3 |
| RIMBP2 | TFE3 | 0.702302 | 3 | 0 | 3 |
| RIMBP2 | LCE1D | 0.694857 | 3 | 0 | 3 |
| RIMBP2 | PANX2 | 0.69123 | 4 | 0 | 4 |
| RIMBP2 | HMX1 | 0.685928 | 3 | 0 | 3 |
| RIMBP2 | SLC26A1 | 0.684346 | 3 | 0 | 3 |
| RIMBP2 | CDR2L | 0.674797 | 3 | 0 | 3 |
| RIMBP2 | CASC15 | 0.670818 | 3 | 0 | 3 |
| RIMBP2 | C8orf74 | 0.670049 | 3 | 0 | 3 |
| RIMBP2 | POLM | 0.66752 | 3 | 0 | 3 |
| RIMBP2 | AGRP | 0.667374 | 3 | 0 | 3 |
| RIMBP2 | FBXO17 | 0.660772 | 3 | 0 | 3 |
For details and further investigation, click here
