| Full name: G protein-coupled receptor class C group 6 member A | Alias Symbol: bA86F4.3 | ||
| Type: protein-coding gene | Cytoband: 6q22.1 | ||
| Entrez ID: 222545 | HGNC ID: HGNC:18510 | Ensembl Gene: ENSG00000173612 | OMIM ID: 613572 |
| Drug and gene relationship at DGIdb | |||
Expression of GPRC6A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GPRC6A | 222545 | 1552775_at | -0.0335 | 0.9239 | |
| GSE26886 | GPRC6A | 222545 | 1552775_at | -0.0672 | 0.6267 | |
| GSE45670 | GPRC6A | 222545 | 1552775_at | 0.1041 | 0.1754 | |
| GSE53622 | GPRC6A | 222545 | 83173 | 0.2825 | 0.3226 | |
| GSE53624 | GPRC6A | 222545 | 83173 | -0.0358 | 0.5695 | |
| GSE63941 | GPRC6A | 222545 | 1552775_at | 0.3387 | 0.0800 | |
| GSE77861 | GPRC6A | 222545 | 1552775_at | -0.0682 | 0.6251 | |
| TCGA | GPRC6A | 222545 | RNAseq | 2.2390 | 0.0711 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GPRC6A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GPRC6A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GPRC6A | 222545 | 1 | 4 | 25 | |
| GSE20123 | GPRC6A | 222545 | 1 | 3 | 26 | |
| GSE43470 | GPRC6A | 222545 | 3 | 1 | 39 | |
| GSE46452 | GPRC6A | 222545 | 2 | 11 | 46 | |
| GSE47630 | GPRC6A | 222545 | 9 | 4 | 27 | |
| GSE54993 | GPRC6A | 222545 | 3 | 2 | 65 | |
| GSE54994 | GPRC6A | 222545 | 8 | 8 | 37 | |
| GSE60625 | GPRC6A | 222545 | 0 | 1 | 10 | |
| GSE74703 | GPRC6A | 222545 | 2 | 1 | 33 | |
| GSE74704 | GPRC6A | 222545 | 0 | 1 | 19 | |
| TCGA | GPRC6A | 222545 | 7 | 22 | 67 |
Total number of gains: 36; Total number of losses: 58; Total Number of normals: 394.
Somatic mutations of GPRC6A:
Generating mutation plots.
Highly correlated genes for GPRC6A:
Showing top 20/33 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GPRC6A | NTRK3 | 0.679958 | 3 | 0 | 3 |
| GPRC6A | ADRA1A | 0.631742 | 3 | 0 | 3 |
| GPRC6A | SERPINA5 | 0.630409 | 3 | 0 | 3 |
| GPRC6A | SAMD15 | 0.628782 | 3 | 0 | 3 |
| GPRC6A | TSGA13 | 0.611416 | 3 | 0 | 3 |
| GPRC6A | HNF1B | 0.609401 | 3 | 0 | 3 |
| GPRC6A | WNK2 | 0.607059 | 3 | 0 | 3 |
| GPRC6A | DCST1 | 0.606285 | 3 | 0 | 3 |
| GPRC6A | TINAGL1 | 0.594061 | 3 | 0 | 3 |
| GPRC6A | NFIA-AS2 | 0.593385 | 4 | 0 | 4 |
| GPRC6A | TRIM36 | 0.591581 | 3 | 0 | 3 |
| GPRC6A | KIF17 | 0.586513 | 3 | 0 | 3 |
| GPRC6A | SYT6 | 0.585794 | 4 | 0 | 3 |
| GPRC6A | CCZ1 | 0.583193 | 3 | 0 | 3 |
| GPRC6A | SIT1 | 0.581238 | 3 | 0 | 3 |
| GPRC6A | OR2J2 | 0.580587 | 3 | 0 | 3 |
| GPRC6A | KLHL30-AS1 | 0.57601 | 3 | 0 | 3 |
| GPRC6A | C11orf72 | 0.571022 | 3 | 0 | 3 |
| GPRC6A | CST8 | 0.567022 | 3 | 0 | 3 |
| GPRC6A | SMCP | 0.562771 | 5 | 0 | 3 |
For details and further investigation, click here
