| Full name: sperm mitochondria associated cysteine rich protein | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1q21.3 | ||
| Entrez ID: 4184 | HGNC ID: HGNC:6962 | Ensembl Gene: ENSG00000163206 | OMIM ID: 601148 |
| Drug and gene relationship at DGIdb | |||
Expression of SMCP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SMCP | 4184 | 206406_at | -0.0621 | 0.8253 | |
| GSE20347 | SMCP | 4184 | 206406_at | 0.0442 | 0.6714 | |
| GSE23400 | SMCP | 4184 | 206406_at | -0.1243 | 0.0020 | |
| GSE26886 | SMCP | 4184 | 206406_at | 0.0317 | 0.8600 | |
| GSE29001 | SMCP | 4184 | 206406_at | -0.1890 | 0.2011 | |
| GSE38129 | SMCP | 4184 | 206406_at | -0.0481 | 0.6408 | |
| GSE45670 | SMCP | 4184 | 206406_at | 0.1630 | 0.1682 | |
| GSE53622 | SMCP | 4184 | 109466 | 0.0379 | 0.7942 | |
| GSE53624 | SMCP | 4184 | 109466 | 0.0536 | 0.5606 | |
| GSE63941 | SMCP | 4184 | 206406_at | 0.3109 | 0.0562 | |
| GSE77861 | SMCP | 4184 | 206406_at | -0.1328 | 0.3224 | |
| GSE97050 | SMCP | 4184 | A_24_P336596 | 0.1646 | 0.4761 | |
| TCGA | SMCP | 4184 | RNAseq | 2.3561 | 0.0371 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by SMCP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SMCP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SMCP | 4184 | 15 | 0 | 15 | |
| GSE20123 | SMCP | 4184 | 15 | 0 | 15 | |
| GSE43470 | SMCP | 4184 | 6 | 2 | 35 | |
| GSE46452 | SMCP | 4184 | 3 | 1 | 55 | |
| GSE47630 | SMCP | 4184 | 15 | 0 | 25 | |
| GSE54993 | SMCP | 4184 | 0 | 4 | 66 | |
| GSE54994 | SMCP | 4184 | 15 | 0 | 38 | |
| GSE60625 | SMCP | 4184 | 0 | 0 | 11 | |
| GSE74703 | SMCP | 4184 | 6 | 1 | 29 | |
| GSE74704 | SMCP | 4184 | 7 | 0 | 13 | |
| TCGA | SMCP | 4184 | 39 | 2 | 55 |
Total number of gains: 121; Total number of losses: 10; Total Number of normals: 357.
Somatic mutations of SMCP:
Generating mutation plots.
Highly correlated genes for SMCP:
Showing top 20/1093 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SMCP | CHIT1 | 0.756011 | 3 | 0 | 3 |
| SMCP | NTNG1 | 0.735553 | 4 | 0 | 4 |
| SMCP | PHF7 | 0.732284 | 5 | 0 | 5 |
| SMCP | HRC | 0.720735 | 5 | 0 | 5 |
| SMCP | SLC5A4 | 0.719284 | 6 | 0 | 6 |
| SMCP | KIR3DL3 | 0.718816 | 7 | 0 | 7 |
| SMCP | OR10C1 | 0.718021 | 6 | 0 | 6 |
| SMCP | MMP21 | 0.717235 | 3 | 0 | 3 |
| SMCP | OR2H2 | 0.709356 | 7 | 0 | 7 |
| SMCP | BTNL9 | 0.706755 | 3 | 0 | 3 |
| SMCP | MAP3K19 | 0.706235 | 7 | 0 | 7 |
| SMCP | KRTAP10-12 | 0.697539 | 3 | 0 | 3 |
| SMCP | SULT2A1 | 0.696767 | 3 | 0 | 3 |
| SMCP | KCNJ3 | 0.696355 | 6 | 0 | 6 |
| SMCP | CIITA | 0.693185 | 6 | 0 | 6 |
| SMCP | ERN1 | 0.691668 | 4 | 0 | 4 |
| SMCP | CLCA1 | 0.690574 | 5 | 0 | 5 |
| SMCP | ZNF81 | 0.690153 | 3 | 0 | 3 |
| SMCP | CRHR2 | 0.68713 | 6 | 0 | 6 |
| SMCP | ENGASE | 0.685285 | 4 | 0 | 3 |
For details and further investigation, click here
