SAMD15

 

Full name: sterile alpha motif domain containing 15 Alias Symbol: FLJ35963
Type: protein-coding gene Cytoband: 14q24.3
Entrez ID: 161394 HGNC ID: HGNC:18631 Ensembl Gene: ENSG00000100583 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of SAMD15:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SAMD15 161394 1557680_at -0.2847 0.2162
GSE26886 SAMD15 161394 1557680_at -0.4862 0.0581
GSE45670 SAMD15 161394 1557680_at 0.0987 0.5681
GSE53622 SAMD15 161394 67402 1.3375 0.0000
GSE53624 SAMD15 161394 67402 1.1952 0.0000
GSE63941 SAMD15 161394 1557680_at 0.3869 0.0695
GSE77861 SAMD15 161394 1557680_at -0.2384 0.1155
GSE97050 SAMD15 161394 A_23_P349025 0.2519 0.2500
SRP133303 SAMD15 161394 RNAseq 1.6720 0.0000
SRP159526 SAMD15 161394 RNAseq 1.8997 0.0002

Upregulated datasets: 4; Downregulated datasets: 0.  


 

Survival by SAMD15 expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  


Copy number change of SAMD15:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SAMD15 161394 8 3 19
GSE20123 SAMD15 161394 8 3 19
GSE43470 SAMD15 161394 8 3 32
GSE46452 SAMD15 161394 16 3 40
GSE47630 SAMD15 161394 11 8 21
GSE54993 SAMD15 161394 3 8 59
GSE54994 SAMD15 161394 19 4 30
GSE60625 SAMD15 161394 0 2 9
GSE74703 SAMD15 161394 7 3 26
GSE74704 SAMD15 161394 3 3 14
TCGA SAMD15 161394 32 16 48

Total number of gains: 115; Total number of losses: 56; Total Number of normals: 317.  


 

Somatic mutations of SAMD15:

 

Generating mutation plots.

 

Highly correlated genes for SAMD15:

 

Showing top 20/174 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SAMD15EMCN0.766501303
SAMD15MYCN0.726906303
SAMD15SIRPG0.719124303
SAMD15DMBT10.711994303
SAMD15CACNG60.704744404
SAMD15TOM1L10.699983403
SAMD15CYP2A70.699811404
SAMD15ZFPL10.697169303
SAMD15PZP0.695626403
SAMD15UBE2NL0.692853303
SAMD15MPV17L0.685286403
SAMD15APOB0.675497404
SAMD15TMC20.672496504
SAMD15IQCC0.669864303
SAMD15GNG100.668314303
SAMD15SLC4A80.662694403
SAMD15PLS10.662101303
SAMD15PRSS330.661618303
SAMD15MRGPRX40.659795303
SAMD15CSMD2-AS10.658572303

For details and further investigation, click here