| Full name: histone deacetylase 10 | Alias Symbol: DKFZP761B039 | ||
| Type: protein-coding gene | Cytoband: 22q13.33 | ||
| Entrez ID: 83933 | HGNC ID: HGNC:18128 | Ensembl Gene: ENSG00000100429 | OMIM ID: 608544 |
| Drug and gene relationship at DGIdb | |||
Expression of HDAC10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HDAC10 | 83933 | 226672_s_at | 0.1320 | 0.6321 | |
| GSE26886 | HDAC10 | 83933 | 232870_at | 0.3343 | 0.0238 | |
| GSE45670 | HDAC10 | 83933 | 232870_at | 0.0315 | 0.7355 | |
| GSE53622 | HDAC10 | 83933 | 63686 | 0.5432 | 0.0000 | |
| GSE53624 | HDAC10 | 83933 | 63686 | 0.6711 | 0.0000 | |
| GSE63941 | HDAC10 | 83933 | 226672_s_at | 0.2998 | 0.1100 | |
| GSE77861 | HDAC10 | 83933 | 226672_s_at | -0.0597 | 0.6647 | |
| GSE97050 | HDAC10 | 83933 | A_23_P368740 | -0.0408 | 0.8840 | |
| SRP007169 | HDAC10 | 83933 | RNAseq | 0.0838 | 0.8862 | |
| SRP008496 | HDAC10 | 83933 | RNAseq | -0.0761 | 0.8375 | |
| SRP064894 | HDAC10 | 83933 | RNAseq | 1.0341 | 0.0000 | |
| SRP133303 | HDAC10 | 83933 | RNAseq | -0.0826 | 0.5319 | |
| SRP159526 | HDAC10 | 83933 | RNAseq | 0.2426 | 0.2125 | |
| SRP193095 | HDAC10 | 83933 | RNAseq | 0.4662 | 0.0034 | |
| SRP219564 | HDAC10 | 83933 | RNAseq | 0.9181 | 0.0115 | |
| TCGA | HDAC10 | 83933 | RNAseq | 0.1386 | 0.0330 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by HDAC10 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HDAC10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HDAC10 | 83933 | 3 | 8 | 19 | |
| GSE20123 | HDAC10 | 83933 | 3 | 8 | 19 | |
| GSE43470 | HDAC10 | 83933 | 2 | 8 | 33 | |
| GSE46452 | HDAC10 | 83933 | 31 | 2 | 26 | |
| GSE47630 | HDAC10 | 83933 | 9 | 4 | 27 | |
| GSE54993 | HDAC10 | 83933 | 4 | 6 | 60 | |
| GSE54994 | HDAC10 | 83933 | 11 | 8 | 34 | |
| GSE60625 | HDAC10 | 83933 | 5 | 0 | 6 | |
| GSE74703 | HDAC10 | 83933 | 2 | 6 | 28 | |
| GSE74704 | HDAC10 | 83933 | 1 | 4 | 15 | |
| TCGA | HDAC10 | 83933 | 26 | 16 | 54 |
Total number of gains: 97; Total number of losses: 70; Total Number of normals: 321.
Somatic mutations of HDAC10:
Generating mutation plots.
Highly correlated genes for HDAC10:
Showing top 20/362 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HDAC10 | MGAT5B | 0.831296 | 3 | 0 | 3 |
| HDAC10 | TTC9B | 0.80383 | 3 | 0 | 3 |
| HDAC10 | AIRE | 0.775375 | 3 | 0 | 3 |
| HDAC10 | CPAMD8 | 0.767321 | 3 | 0 | 3 |
| HDAC10 | MEX3D | 0.765867 | 4 | 0 | 3 |
| HDAC10 | FUT7 | 0.753824 | 4 | 0 | 4 |
| HDAC10 | HOXB9 | 0.745749 | 4 | 0 | 4 |
| HDAC10 | AMN | 0.737484 | 3 | 0 | 3 |
| HDAC10 | DUSP15 | 0.723655 | 3 | 0 | 3 |
| HDAC10 | ELAVL3 | 0.722378 | 4 | 0 | 4 |
| HDAC10 | TNNC2 | 0.721644 | 3 | 0 | 3 |
| HDAC10 | LTB4R2 | 0.716561 | 4 | 0 | 3 |
| HDAC10 | DNAJC22 | 0.713078 | 4 | 0 | 4 |
| HDAC10 | ZMYND10 | 0.712375 | 3 | 0 | 3 |
| HDAC10 | P2RY4 | 0.71185 | 3 | 0 | 3 |
| HDAC10 | HGD | 0.709828 | 3 | 0 | 3 |
| HDAC10 | JSRP1 | 0.708905 | 5 | 0 | 4 |
| HDAC10 | NKAIN4 | 0.708007 | 4 | 0 | 4 |
| HDAC10 | UPB1 | 0.705593 | 4 | 0 | 4 |
| HDAC10 | HK3 | 0.699624 | 3 | 0 | 3 |
For details and further investigation, click here
