| Full name: mex-3 RNA binding family member D | Alias Symbol: Tino|KIAA2031|OK/SW-cl.4|RNF193 | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 399664 | HGNC ID: HGNC:16734 | Ensembl Gene: ENSG00000181588 | OMIM ID: 611009 |
| Drug and gene relationship at DGIdb | |||
Expression of MEX3D:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MEX3D | 399664 | 91816_f_at | 1.1268 | 0.0296 | |
| GSE20347 | MEX3D | 399664 | 222042_x_at | -0.0177 | 0.7998 | |
| GSE23400 | MEX3D | 399664 | 91816_f_at | 0.8835 | 0.0000 | |
| GSE26886 | MEX3D | 399664 | 222042_x_at | 0.4347 | 0.0022 | |
| GSE29001 | MEX3D | 399664 | 91816_f_at | 0.7050 | 0.0144 | |
| GSE38129 | MEX3D | 399664 | 91816_f_at | 1.1082 | 0.0009 | |
| GSE45670 | MEX3D | 399664 | 91816_f_at | 0.4934 | 0.0045 | |
| GSE53622 | MEX3D | 399664 | 13041 | 0.0081 | 0.8688 | |
| GSE53624 | MEX3D | 399664 | 13041 | 0.0748 | 0.1558 | |
| GSE63941 | MEX3D | 399664 | 91816_f_at | -0.8406 | 0.1687 | |
| GSE77861 | MEX3D | 399664 | 222042_x_at | -0.0606 | 0.7060 | |
| GSE97050 | MEX3D | 399664 | A_33_P3262555 | 0.0546 | 0.8143 | |
| SRP007169 | MEX3D | 399664 | RNAseq | -0.4311 | 0.2281 | |
| SRP008496 | MEX3D | 399664 | RNAseq | -0.0999 | 0.6805 | |
| SRP064894 | MEX3D | 399664 | RNAseq | 0.9663 | 0.0002 | |
| SRP133303 | MEX3D | 399664 | RNAseq | 0.9404 | 0.0002 | |
| SRP159526 | MEX3D | 399664 | RNAseq | 0.7512 | 0.0143 | |
| SRP193095 | MEX3D | 399664 | RNAseq | 0.4889 | 0.0046 | |
| SRP219564 | MEX3D | 399664 | RNAseq | 0.6323 | 0.0077 | |
| TCGA | MEX3D | 399664 | RNAseq | 0.2545 | 0.0001 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by MEX3D expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MEX3D:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MEX3D | 399664 | 4 | 6 | 20 | |
| GSE20123 | MEX3D | 399664 | 4 | 5 | 21 | |
| GSE43470 | MEX3D | 399664 | 1 | 11 | 31 | |
| GSE46452 | MEX3D | 399664 | 47 | 1 | 11 | |
| GSE47630 | MEX3D | 399664 | 5 | 7 | 28 | |
| GSE54993 | MEX3D | 399664 | 16 | 3 | 51 | |
| GSE54994 | MEX3D | 399664 | 8 | 15 | 30 | |
| GSE60625 | MEX3D | 399664 | 9 | 0 | 2 | |
| GSE74703 | MEX3D | 399664 | 1 | 8 | 27 | |
| GSE74704 | MEX3D | 399664 | 3 | 3 | 14 | |
| TCGA | MEX3D | 399664 | 6 | 25 | 65 |
Total number of gains: 104; Total number of losses: 84; Total Number of normals: 300.
Somatic mutations of MEX3D:
Generating mutation plots.
Highly correlated genes for MEX3D:
Showing top 20/400 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MEX3D | MGAT5B | 0.881685 | 3 | 0 | 3 |
| MEX3D | GAS6-AS1 | 0.776021 | 3 | 0 | 3 |
| MEX3D | SPRED3 | 0.772361 | 4 | 0 | 4 |
| MEX3D | RASL10B | 0.769435 | 4 | 0 | 4 |
| MEX3D | HDAC10 | 0.765867 | 4 | 0 | 3 |
| MEX3D | NOBOX | 0.759466 | 3 | 0 | 3 |
| MEX3D | AP2A1 | 0.734184 | 3 | 0 | 3 |
| MEX3D | PHGR1 | 0.731563 | 3 | 0 | 3 |
| MEX3D | RCOR2 | 0.730022 | 3 | 0 | 3 |
| MEX3D | MAFA | 0.727399 | 3 | 0 | 3 |
| MEX3D | C4orf46 | 0.723219 | 3 | 0 | 3 |
| MEX3D | TNFAIP8L1 | 0.721235 | 5 | 0 | 5 |
| MEX3D | PPP1R12C | 0.717465 | 3 | 0 | 3 |
| MEX3D | CABP4 | 0.715882 | 3 | 0 | 3 |
| MEX3D | SIX1 | 0.714881 | 4 | 0 | 4 |
| MEX3D | BAX | 0.713661 | 6 | 0 | 5 |
| MEX3D | LAT | 0.713499 | 3 | 0 | 3 |
| MEX3D | MYBL2 | 0.712355 | 5 | 0 | 5 |
| MEX3D | FAM53A | 0.710015 | 3 | 0 | 3 |
| MEX3D | ZIC1 | 0.709708 | 5 | 0 | 4 |
For details and further investigation, click here
