| Full name: C3 and PZP like alpha-2-macroglobulin domain containing 8 | Alias Symbol: KIAA1283|VIP|K-CAP | ||
| Type: protein-coding gene | Cytoband: 19p13.11 | ||
| Entrez ID: 27151 | HGNC ID: HGNC:23228 | Ensembl Gene: ENSG00000160111 | OMIM ID: 608841 |
| Drug and gene relationship at DGIdb | |||
Expression of CPAMD8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CPAMD8 | 27151 | 227721_at | 0.4408 | 0.5438 | |
| GSE26886 | CPAMD8 | 27151 | 227721_at | 0.8037 | 0.0000 | |
| GSE45670 | CPAMD8 | 27151 | 227721_at | 0.0080 | 0.9686 | |
| GSE53622 | CPAMD8 | 27151 | 39772 | 0.2489 | 0.0238 | |
| GSE53624 | CPAMD8 | 27151 | 39772 | 0.3223 | 0.0012 | |
| GSE63941 | CPAMD8 | 27151 | 227721_at | 0.4053 | 0.1625 | |
| GSE77861 | CPAMD8 | 27151 | 227721_at | -0.0497 | 0.6790 | |
| GSE97050 | CPAMD8 | 27151 | A_33_P3290898 | 0.0460 | 0.8395 | |
| SRP064894 | CPAMD8 | 27151 | RNAseq | 1.0389 | 0.0049 | |
| SRP133303 | CPAMD8 | 27151 | RNAseq | -0.5808 | 0.0854 | |
| SRP193095 | CPAMD8 | 27151 | RNAseq | 0.5483 | 0.0551 | |
| SRP219564 | CPAMD8 | 27151 | RNAseq | 2.6305 | 0.0020 | |
| TCGA | CPAMD8 | 27151 | RNAseq | -0.4187 | 0.0637 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by CPAMD8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CPAMD8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CPAMD8 | 27151 | 4 | 4 | 22 | |
| GSE20123 | CPAMD8 | 27151 | 3 | 2 | 25 | |
| GSE43470 | CPAMD8 | 27151 | 2 | 6 | 35 | |
| GSE46452 | CPAMD8 | 27151 | 47 | 1 | 11 | |
| GSE47630 | CPAMD8 | 27151 | 4 | 8 | 28 | |
| GSE54993 | CPAMD8 | 27151 | 15 | 4 | 51 | |
| GSE54994 | CPAMD8 | 27151 | 6 | 14 | 33 | |
| GSE60625 | CPAMD8 | 27151 | 9 | 0 | 2 | |
| GSE74703 | CPAMD8 | 27151 | 2 | 4 | 30 | |
| GSE74704 | CPAMD8 | 27151 | 0 | 1 | 19 | |
| TCGA | CPAMD8 | 27151 | 17 | 9 | 70 |
Total number of gains: 109; Total number of losses: 53; Total Number of normals: 326.
Somatic mutations of CPAMD8:
Generating mutation plots.
Highly correlated genes for CPAMD8:
Showing top 20/277 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CPAMD8 | PGC | 0.842015 | 3 | 0 | 3 |
| CPAMD8 | LRFN3 | 0.83016 | 3 | 0 | 3 |
| CPAMD8 | SHARPIN | 0.820157 | 4 | 0 | 4 |
| CPAMD8 | DHX34 | 0.816674 | 3 | 0 | 3 |
| CPAMD8 | MAPK8IP2 | 0.814937 | 3 | 0 | 3 |
| CPAMD8 | ZNF444 | 0.808755 | 4 | 0 | 4 |
| CPAMD8 | JSRP1 | 0.804179 | 3 | 0 | 3 |
| CPAMD8 | REG3A | 0.799827 | 3 | 0 | 3 |
| CPAMD8 | SCUBE1 | 0.797038 | 3 | 0 | 3 |
| CPAMD8 | LONP1 | 0.79604 | 3 | 0 | 3 |
| CPAMD8 | PICK1 | 0.788531 | 3 | 0 | 3 |
| CPAMD8 | PRPF31 | 0.78537 | 3 | 0 | 3 |
| CPAMD8 | PNMA3 | 0.776179 | 3 | 0 | 3 |
| CPAMD8 | FBRSL1 | 0.772275 | 4 | 0 | 4 |
| CPAMD8 | CCNJL | 0.768813 | 3 | 0 | 3 |
| CPAMD8 | TNNC2 | 0.768703 | 3 | 0 | 3 |
| CPAMD8 | HDAC10 | 0.767321 | 3 | 0 | 3 |
| CPAMD8 | PKDREJ | 0.766755 | 3 | 0 | 3 |
| CPAMD8 | PGP | 0.766602 | 3 | 0 | 3 |
| CPAMD8 | ZNF341 | 0.761564 | 3 | 0 | 3 |
For details and further investigation, click here
