| Full name: dual specificity phosphatase 15 | Alias Symbol: bA243J16.6|VHY|FLJ20645|bA243J16.5 | ||
| Type: protein-coding gene | Cytoband: 20q11.21 | ||
| Entrez ID: 128853 | HGNC ID: HGNC:16236 | Ensembl Gene: ENSG00000149599 | OMIM ID: 616776 |
| Drug and gene relationship at DGIdb | |||
Expression of DUSP15:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DUSP15 | 128853 | 230402_at | -0.0245 | 0.9307 | |
| GSE26886 | DUSP15 | 128853 | 230402_at | 0.3797 | 0.0179 | |
| GSE45670 | DUSP15 | 128853 | 230402_at | -0.0168 | 0.8749 | |
| GSE53622 | DUSP15 | 128853 | 8686 | -0.1257 | 0.0155 | |
| GSE53624 | DUSP15 | 128853 | 8686 | -0.0176 | 0.7012 | |
| GSE63941 | DUSP15 | 128853 | 230402_at | 0.1450 | 0.5244 | |
| GSE77861 | DUSP15 | 128853 | 230402_at | -0.0716 | 0.7185 | |
| GSE97050 | DUSP15 | 128853 | A_23_P154771 | -0.1290 | 0.5861 | |
| SRP159526 | DUSP15 | 128853 | RNAseq | 1.6370 | 0.0308 | |
| SRP219564 | DUSP15 | 128853 | RNAseq | 0.4842 | 0.5738 | |
| TCGA | DUSP15 | 128853 | RNAseq | -0.9441 | 0.0257 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by DUSP15 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DUSP15:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DUSP15 | 128853 | 15 | 0 | 15 | |
| GSE20123 | DUSP15 | 128853 | 15 | 0 | 15 | |
| GSE43470 | DUSP15 | 128853 | 11 | 0 | 32 | |
| GSE46452 | DUSP15 | 128853 | 29 | 0 | 30 | |
| GSE47630 | DUSP15 | 128853 | 25 | 0 | 15 | |
| GSE54993 | DUSP15 | 128853 | 0 | 18 | 52 | |
| GSE54994 | DUSP15 | 128853 | 27 | 1 | 25 | |
| GSE60625 | DUSP15 | 128853 | 0 | 0 | 11 | |
| GSE74703 | DUSP15 | 128853 | 10 | 0 | 26 | |
| GSE74704 | DUSP15 | 128853 | 10 | 0 | 10 | |
| TCGA | DUSP15 | 128853 | 49 | 1 | 46 |
Total number of gains: 191; Total number of losses: 20; Total Number of normals: 277.
Somatic mutations of DUSP15:
Generating mutation plots.
Highly correlated genes for DUSP15:
Showing top 20/288 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DUSP15 | PCDH1 | 0.821247 | 3 | 0 | 3 |
| DUSP15 | WNT9A | 0.803731 | 3 | 0 | 3 |
| DUSP15 | TUT1 | 0.797385 | 3 | 0 | 3 |
| DUSP15 | SCN2B | 0.78958 | 3 | 0 | 3 |
| DUSP15 | LIM2 | 0.781201 | 3 | 0 | 3 |
| DUSP15 | LRRC46 | 0.778093 | 3 | 0 | 3 |
| DUSP15 | OR1F1 | 0.777533 | 3 | 0 | 3 |
| DUSP15 | CABP1 | 0.764129 | 3 | 0 | 3 |
| DUSP15 | PPP1R3F | 0.763977 | 3 | 0 | 3 |
| DUSP15 | TNXB | 0.750814 | 4 | 0 | 4 |
| DUSP15 | AGER | 0.747941 | 4 | 0 | 4 |
| DUSP15 | FUZ | 0.741923 | 3 | 0 | 3 |
| DUSP15 | EVX1 | 0.741511 | 5 | 0 | 5 |
| DUSP15 | CARD14 | 0.73654 | 3 | 0 | 3 |
| DUSP15 | ZNF524 | 0.73567 | 4 | 0 | 4 |
| DUSP15 | GNL1 | 0.733516 | 3 | 0 | 3 |
| DUSP15 | ZNF157 | 0.730489 | 3 | 0 | 3 |
| DUSP15 | MAPK8IP2 | 0.729433 | 3 | 0 | 3 |
| DUSP15 | HDAC10 | 0.723655 | 3 | 0 | 3 |
| DUSP15 | HOXD9 | 0.721403 | 3 | 0 | 3 |
For details and further investigation, click here
