| Full name: high mobility group 20B | Alias Symbol: SOXL|HMGX2|BRAF35|SMARCE1r|BRAF25|HMGXB2 | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 10362 | HGNC ID: HGNC:5002 | Ensembl Gene: ENSG00000064961 | OMIM ID: 605535 |
| Drug and gene relationship at DGIdb | |||
Expression of HMG20B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HMG20B | 10362 | 210719_s_at | 0.2607 | 0.5785 | |
| GSE20347 | HMG20B | 10362 | 210719_s_at | 0.4808 | 0.0033 | |
| GSE23400 | HMG20B | 10362 | 210719_s_at | 0.4582 | 0.0000 | |
| GSE26886 | HMG20B | 10362 | 210719_s_at | 0.8174 | 0.0014 | |
| GSE29001 | HMG20B | 10362 | 210719_s_at | 0.3404 | 0.4375 | |
| GSE38129 | HMG20B | 10362 | 210719_s_at | 0.3990 | 0.0005 | |
| GSE45670 | HMG20B | 10362 | 210719_s_at | 0.4971 | 0.0137 | |
| GSE53622 | HMG20B | 10362 | 22373 | 0.0278 | 0.7280 | |
| GSE53624 | HMG20B | 10362 | 22373 | 0.2648 | 0.0000 | |
| GSE63941 | HMG20B | 10362 | 210719_s_at | 1.3653 | 0.0022 | |
| GSE77861 | HMG20B | 10362 | 210719_s_at | 0.9425 | 0.0009 | |
| GSE97050 | HMG20B | 10362 | A_33_P3394599 | 0.2291 | 0.4785 | |
| SRP007169 | HMG20B | 10362 | RNAseq | 0.2244 | 0.5257 | |
| SRP008496 | HMG20B | 10362 | RNAseq | 0.3330 | 0.1161 | |
| SRP064894 | HMG20B | 10362 | RNAseq | 0.5849 | 0.0192 | |
| SRP133303 | HMG20B | 10362 | RNAseq | 0.2810 | 0.1018 | |
| SRP159526 | HMG20B | 10362 | RNAseq | 0.3838 | 0.1695 | |
| SRP193095 | HMG20B | 10362 | RNAseq | 0.4940 | 0.0000 | |
| SRP219564 | HMG20B | 10362 | RNAseq | 0.0876 | 0.8497 | |
| TCGA | HMG20B | 10362 | RNAseq | 0.0749 | 0.1250 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by HMG20B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HMG20B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HMG20B | 10362 | 5 | 3 | 22 | |
| GSE20123 | HMG20B | 10362 | 4 | 2 | 24 | |
| GSE43470 | HMG20B | 10362 | 1 | 9 | 33 | |
| GSE46452 | HMG20B | 10362 | 47 | 1 | 11 | |
| GSE47630 | HMG20B | 10362 | 5 | 7 | 28 | |
| GSE54993 | HMG20B | 10362 | 16 | 3 | 51 | |
| GSE54994 | HMG20B | 10362 | 8 | 16 | 29 | |
| GSE60625 | HMG20B | 10362 | 9 | 0 | 2 | |
| GSE74703 | HMG20B | 10362 | 1 | 6 | 29 | |
| GSE74704 | HMG20B | 10362 | 1 | 2 | 17 | |
| TCGA | HMG20B | 10362 | 10 | 19 | 67 |
Total number of gains: 107; Total number of losses: 68; Total Number of normals: 313.
Somatic mutations of HMG20B:
Generating mutation plots.
Highly correlated genes for HMG20B:
Showing top 20/1269 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HMG20B | GAS2L1 | 0.790495 | 3 | 0 | 3 |
| HMG20B | ZNF202 | 0.788985 | 3 | 0 | 3 |
| HMG20B | NIPA1 | 0.763581 | 3 | 0 | 3 |
| HMG20B | TINAGL1 | 0.759086 | 3 | 0 | 3 |
| HMG20B | DMWD | 0.753854 | 3 | 0 | 3 |
| HMG20B | TRAPPC1 | 0.745092 | 3 | 0 | 3 |
| HMG20B | ZBTB8A | 0.744875 | 3 | 0 | 3 |
| HMG20B | BHLHB9 | 0.742108 | 4 | 0 | 3 |
| HMG20B | FOXN2 | 0.731867 | 3 | 0 | 3 |
| HMG20B | AMMECR1L | 0.729823 | 4 | 0 | 4 |
| HMG20B | MB21D2 | 0.726326 | 3 | 0 | 3 |
| HMG20B | MRPL38 | 0.721961 | 3 | 0 | 3 |
| HMG20B | SHANK3 | 0.720828 | 3 | 0 | 3 |
| HMG20B | ALKBH6 | 0.719848 | 5 | 0 | 5 |
| HMG20B | UTP23 | 0.718173 | 3 | 0 | 3 |
| HMG20B | TRMT6 | 0.716513 | 3 | 0 | 3 |
| HMG20B | EXOC3L1 | 0.710325 | 3 | 0 | 3 |
| HMG20B | C9orf16 | 0.709133 | 3 | 0 | 3 |
| HMG20B | ZNF518B | 0.706371 | 3 | 0 | 3 |
| HMG20B | COMMD2 | 0.704392 | 4 | 0 | 4 |
For details and further investigation, click here
