| Full name: alkB homolog 6 | Alias Symbol: MGC15677 | ||
| Type: protein-coding gene | Cytoband: 19q13.12 | ||
| Entrez ID: 84964 | HGNC ID: HGNC:28243 | Ensembl Gene: ENSG00000239382 | OMIM ID: 613304 |
| Drug and gene relationship at DGIdb | |||
Expression of ALKBH6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ALKBH6 | 84964 | 225969_at | 0.2905 | 0.4320 | |
| GSE26886 | ALKBH6 | 84964 | 225969_at | 1.3619 | 0.0000 | |
| GSE45670 | ALKBH6 | 84964 | 225969_at | 0.6246 | 0.0025 | |
| GSE63941 | ALKBH6 | 84964 | 225969_at | 0.5965 | 0.3518 | |
| GSE77861 | ALKBH6 | 84964 | 225969_at | 0.8193 | 0.0013 | |
| GSE97050 | ALKBH6 | 84964 | A_23_P39402 | 0.1953 | 0.3544 | |
| SRP007169 | ALKBH6 | 84964 | RNAseq | 0.6822 | 0.2068 | |
| SRP008496 | ALKBH6 | 84964 | RNAseq | 0.1243 | 0.7738 | |
| SRP064894 | ALKBH6 | 84964 | RNAseq | 1.3389 | 0.0000 | |
| SRP133303 | ALKBH6 | 84964 | RNAseq | 0.1932 | 0.2724 | |
| SRP159526 | ALKBH6 | 84964 | RNAseq | 0.4743 | 0.1326 | |
| SRP193095 | ALKBH6 | 84964 | RNAseq | 0.5069 | 0.0003 | |
| SRP219564 | ALKBH6 | 84964 | RNAseq | 0.2170 | 0.4996 | |
| TCGA | ALKBH6 | 84964 | RNAseq | 0.3048 | 0.0002 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by ALKBH6 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of ALKBH6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ALKBH6 | 84964 | 7 | 4 | 19 | |
| GSE20123 | ALKBH6 | 84964 | 7 | 3 | 20 | |
| GSE43470 | ALKBH6 | 84964 | 3 | 7 | 33 | |
| GSE46452 | ALKBH6 | 84964 | 48 | 1 | 10 | |
| GSE47630 | ALKBH6 | 84964 | 9 | 5 | 26 | |
| GSE54993 | ALKBH6 | 84964 | 17 | 3 | 50 | |
| GSE54994 | ALKBH6 | 84964 | 6 | 9 | 38 | |
| GSE60625 | ALKBH6 | 84964 | 9 | 0 | 2 | |
| GSE74703 | ALKBH6 | 84964 | 3 | 4 | 29 | |
| GSE74704 | ALKBH6 | 84964 | 6 | 1 | 13 | |
| TCGA | ALKBH6 | 84964 | 22 | 10 | 64 |
Total number of gains: 137; Total number of losses: 47; Total Number of normals: 304.
Somatic mutations of ALKBH6:
Generating mutation plots.
Highly correlated genes for ALKBH6:
Showing top 20/1443 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ALKBH6 | SEMA3C | 0.850714 | 3 | 0 | 3 |
| ALKBH6 | FIP1L1 | 0.848561 | 3 | 0 | 3 |
| ALKBH6 | EXOC8 | 0.848533 | 3 | 0 | 3 |
| ALKBH6 | PLEKHA3 | 0.842926 | 3 | 0 | 3 |
| ALKBH6 | GNS | 0.842625 | 3 | 0 | 3 |
| ALKBH6 | DHX36 | 0.823805 | 5 | 0 | 5 |
| ALKBH6 | IKBIP | 0.82356 | 3 | 0 | 3 |
| ALKBH6 | ACBD6 | 0.821695 | 4 | 0 | 4 |
| ALKBH6 | LRCH3 | 0.819085 | 3 | 0 | 3 |
| ALKBH6 | BRCA1 | 0.818857 | 4 | 0 | 4 |
| ALKBH6 | DVL2 | 0.818654 | 3 | 0 | 3 |
| ALKBH6 | ZC3H15 | 0.818622 | 3 | 0 | 3 |
| ALKBH6 | MORC2 | 0.817535 | 5 | 0 | 5 |
| ALKBH6 | UTP23 | 0.817061 | 3 | 0 | 3 |
| ALKBH6 | MFHAS1 | 0.816698 | 4 | 0 | 4 |
| ALKBH6 | CBFA2T2 | 0.815344 | 3 | 0 | 3 |
| ALKBH6 | ANKRD10 | 0.814036 | 3 | 0 | 3 |
| ALKBH6 | PPP1R16A | 0.813649 | 3 | 0 | 3 |
| ALKBH6 | NUAK1 | 0.81237 | 3 | 0 | 3 |
| ALKBH6 | FTSJ3 | 0.810179 | 4 | 0 | 4 |
For details and further investigation, click here
