ZBTB8A

 

Full name: zinc finger and BTB domain containing 8A Alias Symbol: BOZF1|FLJ90065|ZNF916A
Type: protein-coding gene Cytoband: 1p35.1
Entrez ID: 653121 HGNC ID: HGNC:24172 Ensembl Gene: ENSG00000160062 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of ZBTB8A:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ZBTB8A 653121 235142_at -0.1406 0.8214
GSE26886 ZBTB8A 653121 235142_at 0.9054 0.0032
GSE45670 ZBTB8A 653121 235142_at -0.3839 0.0342
GSE53622 ZBTB8A 653121 7604 -0.1575 0.0386
GSE53624 ZBTB8A 653121 7604 0.1216 0.3424
GSE63941 ZBTB8A 653121 235142_at 1.0147 0.0163
GSE77861 ZBTB8A 653121 235142_at 0.0163 0.9573
GSE97050 ZBTB8A 653121 A_33_P3475737 -0.2179 0.4240
SRP007169 ZBTB8A 653121 RNAseq 0.1999 0.6097
SRP008496 ZBTB8A 653121 RNAseq 0.4043 0.0954
SRP064894 ZBTB8A 653121 RNAseq 0.4103 0.0231
SRP133303 ZBTB8A 653121 RNAseq 0.2630 0.1050
SRP159526 ZBTB8A 653121 RNAseq 0.2743 0.4597
SRP193095 ZBTB8A 653121 RNAseq -0.0062 0.9372
SRP219564 ZBTB8A 653121 RNAseq -0.0326 0.9122
TCGA ZBTB8A 653121 RNAseq -0.1766 0.0068

Upregulated datasets: 1; Downregulated datasets: 0.  


 

Survival by ZBTB8A expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of ZBTB8A:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ZBTB8A 653121 2 5 23
GSE20123 ZBTB8A 653121 2 4 24
GSE43470 ZBTB8A 653121 4 6 33
GSE46452 ZBTB8A 653121 5 1 53
GSE47630 ZBTB8A 653121 8 3 29
GSE54993 ZBTB8A 653121 1 1 68
GSE54994 ZBTB8A 653121 11 2 40
GSE60625 ZBTB8A 653121 0 0 11
GSE74703 ZBTB8A 653121 3 3 30
GSE74704 ZBTB8A 653121 1 0 19
TCGA ZBTB8A 653121 12 19 65

Total number of gains: 49; Total number of losses: 44; Total Number of normals: 395.  


 

Somatic mutations of ZBTB8A:

 

Generating mutation plots.

 

Highly correlated genes for ZBTB8A:

 

Showing top 20/257 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ZBTB8ADNAJC240.87081303
ZBTB8ACPSF60.765011303
ZBTB8ARNF1150.761248303
ZBTB8ADUT0.757398303
ZBTB8AMAP3K130.753411303
ZBTB8AZNF3580.752663303
ZBTB8AHMG20B0.744875303
ZBTB8ANSMCE20.742161303
ZBTB8ABCL7A0.737531303
ZBTB8ASMNDC10.732799303
ZBTB8APPP6R30.71473303
ZBTB8ATCF7L20.714081303
ZBTB8AKLF100.713102303
ZBTB8ACCDC1120.710882404
ZBTB8APIGX0.707156404
ZBTB8AFTO0.706327303
ZBTB8ANFE2L10.704609303
ZBTB8AGATC0.703281404
ZBTB8ASPEN0.702183303
ZBTB8ADCUN1D40.700733404

For details and further investigation, click here