| Full name: zinc finger protein 518B | Alias Symbol: KIAA1729 | ||
| Type: protein-coding gene | Cytoband: 4p16.1 | ||
| Entrez ID: 85460 | HGNC ID: HGNC:29365 | Ensembl Gene: ENSG00000178163 | OMIM ID: 617734 |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF518B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF518B | 85460 | 226909_at | 1.0181 | 0.0503 | |
| GSE26886 | ZNF518B | 85460 | 226909_at | 0.6912 | 0.0654 | |
| GSE45670 | ZNF518B | 85460 | 226909_at | 0.6709 | 0.0022 | |
| GSE53622 | ZNF518B | 85460 | 42916 | 0.7239 | 0.0000 | |
| GSE53624 | ZNF518B | 85460 | 42916 | 0.6902 | 0.0000 | |
| GSE63941 | ZNF518B | 85460 | 226909_at | -1.2755 | 0.2793 | |
| GSE77861 | ZNF518B | 85460 | 226909_at | 0.8237 | 0.0116 | |
| GSE97050 | ZNF518B | 85460 | A_32_P144421 | 0.0670 | 0.7698 | |
| SRP007169 | ZNF518B | 85460 | RNAseq | 1.4527 | 0.0001 | |
| SRP008496 | ZNF518B | 85460 | RNAseq | 1.2801 | 0.0001 | |
| SRP064894 | ZNF518B | 85460 | RNAseq | 0.3602 | 0.0472 | |
| SRP133303 | ZNF518B | 85460 | RNAseq | 0.9003 | 0.0000 | |
| SRP159526 | ZNF518B | 85460 | RNAseq | 0.9226 | 0.0000 | |
| SRP193095 | ZNF518B | 85460 | RNAseq | 0.9832 | 0.0000 | |
| SRP219564 | ZNF518B | 85460 | RNAseq | 0.3506 | 0.3100 | |
| TCGA | ZNF518B | 85460 | RNAseq | 0.1765 | 0.1304 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by ZNF518B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF518B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF518B | 85460 | 0 | 17 | 13 | |
| GSE20123 | ZNF518B | 85460 | 0 | 17 | 13 | |
| GSE43470 | ZNF518B | 85460 | 1 | 15 | 27 | |
| GSE46452 | ZNF518B | 85460 | 1 | 36 | 22 | |
| GSE47630 | ZNF518B | 85460 | 1 | 19 | 20 | |
| GSE54993 | ZNF518B | 85460 | 10 | 0 | 60 | |
| GSE54994 | ZNF518B | 85460 | 4 | 12 | 37 | |
| GSE60625 | ZNF518B | 85460 | 0 | 0 | 11 | |
| GSE74703 | ZNF518B | 85460 | 1 | 13 | 22 | |
| GSE74704 | ZNF518B | 85460 | 0 | 10 | 10 | |
| TCGA | ZNF518B | 85460 | 9 | 47 | 40 |
Total number of gains: 27; Total number of losses: 186; Total Number of normals: 275.
Somatic mutations of ZNF518B:
Generating mutation plots.
Highly correlated genes for ZNF518B:
Showing top 20/1185 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF518B | KHSRP | 0.806837 | 3 | 0 | 3 |
| ZNF518B | VPS13C | 0.799967 | 3 | 0 | 3 |
| ZNF518B | MED15 | 0.797671 | 3 | 0 | 3 |
| ZNF518B | CD3EAP | 0.789575 | 3 | 0 | 3 |
| ZNF518B | PCYT1A | 0.78867 | 3 | 0 | 3 |
| ZNF518B | ZBED1 | 0.788158 | 4 | 0 | 4 |
| ZNF518B | HEXA | 0.787424 | 3 | 0 | 3 |
| ZNF518B | RLIM | 0.786255 | 3 | 0 | 3 |
| ZNF518B | PUM1 | 0.783193 | 3 | 0 | 3 |
| ZNF518B | CCDC127 | 0.782806 | 3 | 0 | 3 |
| ZNF518B | TULP4 | 0.780675 | 3 | 0 | 3 |
| ZNF518B | CIC | 0.778418 | 3 | 0 | 3 |
| ZNF518B | NCOR2 | 0.773089 | 4 | 0 | 4 |
| ZNF518B | ULK1 | 0.771591 | 3 | 0 | 3 |
| ZNF518B | HNRNPUL1 | 0.767412 | 3 | 0 | 3 |
| ZNF518B | GNA11 | 0.765669 | 3 | 0 | 3 |
| ZNF518B | SNRNP70 | 0.760429 | 3 | 0 | 3 |
| ZNF518B | GGNBP2 | 0.758752 | 3 | 0 | 3 |
| ZNF518B | WDR81 | 0.758 | 4 | 0 | 4 |
| ZNF518B | RAVER1 | 0.757601 | 3 | 0 | 3 |
For details and further investigation, click here
