| Full name: trafficking protein particle complex 1 | Alias Symbol: MUM2|BET5 | ||
| Type: protein-coding gene | Cytoband: 17p13.1 | ||
| Entrez ID: 58485 | HGNC ID: HGNC:19894 | Ensembl Gene: ENSG00000170043 | OMIM ID: 610969 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of TRAPPC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRAPPC1 | 58485 | 225294_s_at | 0.0906 | 0.7768 | |
| GSE26886 | TRAPPC1 | 58485 | 225294_s_at | 0.6678 | 0.0137 | |
| GSE45670 | TRAPPC1 | 58485 | 225294_s_at | 0.2328 | 0.0720 | |
| GSE53622 | TRAPPC1 | 58485 | 25393 | 0.0576 | 0.3922 | |
| GSE53624 | TRAPPC1 | 58485 | 25393 | 0.0523 | 0.3725 | |
| GSE63941 | TRAPPC1 | 58485 | 225294_s_at | 3.5545 | 0.0000 | |
| GSE77861 | TRAPPC1 | 58485 | 225294_s_at | 0.0164 | 0.9706 | |
| GSE97050 | TRAPPC1 | 58485 | A_23_P125348 | 0.2681 | 0.2971 | |
| SRP007169 | TRAPPC1 | 58485 | RNAseq | -0.6151 | 0.0696 | |
| SRP008496 | TRAPPC1 | 58485 | RNAseq | -0.4649 | 0.0087 | |
| SRP064894 | TRAPPC1 | 58485 | RNAseq | 0.7575 | 0.0145 | |
| SRP133303 | TRAPPC1 | 58485 | RNAseq | 0.1122 | 0.5374 | |
| SRP159526 | TRAPPC1 | 58485 | RNAseq | -0.1282 | 0.4095 | |
| SRP193095 | TRAPPC1 | 58485 | RNAseq | -0.1228 | 0.4276 | |
| SRP219564 | TRAPPC1 | 58485 | RNAseq | 0.4074 | 0.2713 | |
| TCGA | TRAPPC1 | 58485 | RNAseq | 0.0955 | 0.0680 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by TRAPPC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TRAPPC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRAPPC1 | 58485 | 4 | 2 | 24 | |
| GSE20123 | TRAPPC1 | 58485 | 4 | 3 | 23 | |
| GSE43470 | TRAPPC1 | 58485 | 1 | 6 | 36 | |
| GSE46452 | TRAPPC1 | 58485 | 34 | 1 | 24 | |
| GSE47630 | TRAPPC1 | 58485 | 7 | 1 | 32 | |
| GSE54993 | TRAPPC1 | 58485 | 4 | 3 | 63 | |
| GSE54994 | TRAPPC1 | 58485 | 5 | 8 | 40 | |
| GSE60625 | TRAPPC1 | 58485 | 4 | 0 | 7 | |
| GSE74703 | TRAPPC1 | 58485 | 1 | 3 | 32 | |
| GSE74704 | TRAPPC1 | 58485 | 2 | 1 | 17 | |
| TCGA | TRAPPC1 | 58485 | 17 | 21 | 58 |
Total number of gains: 83; Total number of losses: 49; Total Number of normals: 356.
Somatic mutations of TRAPPC1:
Generating mutation plots.
Highly correlated genes for TRAPPC1:
Showing top 20/386 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRAPPC1 | SNRPA | 0.866608 | 3 | 0 | 3 |
| TRAPPC1 | WBP2 | 0.817718 | 3 | 0 | 3 |
| TRAPPC1 | TRAP1 | 0.803752 | 3 | 0 | 3 |
| TRAPPC1 | PRKCSH | 0.801991 | 4 | 0 | 4 |
| TRAPPC1 | TRIM28 | 0.791773 | 3 | 0 | 3 |
| TRAPPC1 | PRMT1 | 0.790186 | 3 | 0 | 3 |
| TRAPPC1 | ZNF467 | 0.783383 | 3 | 0 | 3 |
| TRAPPC1 | TRMT2B | 0.774153 | 3 | 0 | 3 |
| TRAPPC1 | CBLC | 0.771233 | 3 | 0 | 3 |
| TRAPPC1 | FPGS | 0.759501 | 3 | 0 | 3 |
| TRAPPC1 | ARHGEF16 | 0.756658 | 4 | 0 | 4 |
| TRAPPC1 | RPL29 | 0.755435 | 3 | 0 | 3 |
| TRAPPC1 | MAP2K2 | 0.750243 | 4 | 0 | 3 |
| TRAPPC1 | GGN | 0.749567 | 3 | 0 | 3 |
| TRAPPC1 | COPZ1 | 0.748962 | 3 | 0 | 3 |
| TRAPPC1 | SPRYD4 | 0.748112 | 3 | 0 | 3 |
| TRAPPC1 | HMG20B | 0.745092 | 3 | 0 | 3 |
| TRAPPC1 | NUCB1 | 0.742659 | 3 | 0 | 3 |
| TRAPPC1 | INPP5K | 0.742244 | 3 | 0 | 3 |
| TRAPPC1 | EFNA1 | 0.735081 | 3 | 0 | 3 |
For details and further investigation, click here
