| Full name: mitochondrial ribosomal protein L38 | Alias Symbol: RPML3|MRP-L3|HSPC262|MGC4810 | ||
| Type: protein-coding gene | Cytoband: 17q25.1 | ||
| Entrez ID: 64978 | HGNC ID: HGNC:14033 | Ensembl Gene: ENSG00000204316 | OMIM ID: 611844 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of MRPL38:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MRPL38 | 64978 | 225103_at | 0.4419 | 0.4640 | |
| GSE26886 | MRPL38 | 64978 | 225103_at | 0.0921 | 0.7691 | |
| GSE45670 | MRPL38 | 64978 | 225103_at | 0.0219 | 0.9293 | |
| GSE63941 | MRPL38 | 64978 | 225103_at | 3.8026 | 0.0000 | |
| GSE77861 | MRPL38 | 64978 | 225103_at | 0.2525 | 0.2487 | |
| GSE97050 | MRPL38 | 64978 | A_23_P54963 | 0.0643 | 0.8059 | |
| SRP007169 | MRPL38 | 64978 | RNAseq | 0.0154 | 0.9654 | |
| SRP008496 | MRPL38 | 64978 | RNAseq | -0.3205 | 0.2581 | |
| SRP064894 | MRPL38 | 64978 | RNAseq | 0.4893 | 0.0617 | |
| SRP133303 | MRPL38 | 64978 | RNAseq | 0.3174 | 0.1605 | |
| SRP159526 | MRPL38 | 64978 | RNAseq | 0.3179 | 0.1374 | |
| SRP193095 | MRPL38 | 64978 | RNAseq | 0.1307 | 0.2023 | |
| SRP219564 | MRPL38 | 64978 | RNAseq | -0.1054 | 0.6814 | |
| TCGA | MRPL38 | 64978 | RNAseq | 0.0503 | 0.3252 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by MRPL38 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of MRPL38:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MRPL38 | 64978 | 7 | 2 | 21 | |
| GSE20123 | MRPL38 | 64978 | 7 | 2 | 21 | |
| GSE43470 | MRPL38 | 64978 | 5 | 3 | 35 | |
| GSE46452 | MRPL38 | 64978 | 34 | 0 | 25 | |
| GSE47630 | MRPL38 | 64978 | 8 | 1 | 31 | |
| GSE54993 | MRPL38 | 64978 | 2 | 5 | 63 | |
| GSE54994 | MRPL38 | 64978 | 10 | 4 | 39 | |
| GSE60625 | MRPL38 | 64978 | 6 | 0 | 5 | |
| GSE74703 | MRPL38 | 64978 | 5 | 1 | 30 | |
| GSE74704 | MRPL38 | 64978 | 5 | 1 | 14 | |
| TCGA | MRPL38 | 64978 | 31 | 10 | 55 |
Total number of gains: 120; Total number of losses: 29; Total Number of normals: 339.
Somatic mutations of MRPL38:
Generating mutation plots.
Highly correlated genes for MRPL38:
Showing top 20/708 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MRPL38 | CSNK2B | 0.831402 | 3 | 0 | 3 |
| MRPL38 | OCEL1 | 0.830691 | 3 | 0 | 3 |
| MRPL38 | BANF1 | 0.826358 | 4 | 0 | 4 |
| MRPL38 | CWF19L1 | 0.823961 | 3 | 0 | 3 |
| MRPL38 | SPTAN1 | 0.822487 | 3 | 0 | 3 |
| MRPL38 | POLA1 | 0.815925 | 3 | 0 | 3 |
| MRPL38 | DDB1 | 0.809819 | 3 | 0 | 3 |
| MRPL38 | PPP5C | 0.8085 | 5 | 0 | 5 |
| MRPL38 | AFTPH | 0.803784 | 3 | 0 | 3 |
| MRPL38 | PDAP1 | 0.803672 | 4 | 0 | 4 |
| MRPL38 | ELAVL1 | 0.803069 | 3 | 0 | 3 |
| MRPL38 | PHB2 | 0.801479 | 4 | 0 | 4 |
| MRPL38 | ZNF484 | 0.800973 | 3 | 0 | 3 |
| MRPL38 | LSR | 0.800176 | 3 | 0 | 3 |
| MRPL38 | TUBGCP4 | 0.799578 | 3 | 0 | 3 |
| MRPL38 | FBXO16 | 0.799132 | 3 | 0 | 3 |
| MRPL38 | CNOT1 | 0.797817 | 3 | 0 | 3 |
| MRPL38 | ZNF594 | 0.793761 | 3 | 0 | 3 |
| MRPL38 | KLF16 | 0.79329 | 3 | 0 | 3 |
| MRPL38 | RNF126 | 0.792818 | 3 | 0 | 3 |
For details and further investigation, click here
