| Full name: UTP23 small subunit processome component | Alias Symbol: MGC14595 | ||
| Type: protein-coding gene | Cytoband: 8q24.11 | ||
| Entrez ID: 84294 | HGNC ID: HGNC:28224 | Ensembl Gene: ENSG00000147679 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of UTP23:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UTP23 | 84294 | 227402_s_at | 0.8017 | 0.2960 | |
| GSE26886 | UTP23 | 84294 | 227836_at | 0.4881 | 0.2623 | |
| GSE45670 | UTP23 | 84294 | 227836_at | 0.0475 | 0.8384 | |
| GSE53622 | UTP23 | 84294 | 121745 | 0.7678 | 0.0000 | |
| GSE53624 | UTP23 | 84294 | 121745 | 0.9379 | 0.0000 | |
| GSE63941 | UTP23 | 84294 | 227836_at | -0.0726 | 0.8956 | |
| GSE77861 | UTP23 | 84294 | 227402_s_at | 0.3596 | 0.0250 | |
| GSE97050 | UTP23 | 84294 | A_23_P157679 | 0.2580 | 0.3113 | |
| SRP007169 | UTP23 | 84294 | RNAseq | 0.3120 | 0.3766 | |
| SRP008496 | UTP23 | 84294 | RNAseq | 0.6259 | 0.0072 | |
| SRP064894 | UTP23 | 84294 | RNAseq | 0.4787 | 0.0183 | |
| SRP133303 | UTP23 | 84294 | RNAseq | 0.5683 | 0.0000 | |
| SRP159526 | UTP23 | 84294 | RNAseq | 0.3854 | 0.1479 | |
| SRP193095 | UTP23 | 84294 | RNAseq | 0.3067 | 0.0100 | |
| SRP219564 | UTP23 | 84294 | RNAseq | 0.5205 | 0.0958 | |
| TCGA | UTP23 | 84294 | RNAseq | 0.1197 | 0.0323 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by UTP23 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UTP23:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UTP23 | 84294 | 18 | 1 | 11 | |
| GSE20123 | UTP23 | 84294 | 19 | 1 | 10 | |
| GSE43470 | UTP23 | 84294 | 22 | 0 | 21 | |
| GSE46452 | UTP23 | 84294 | 26 | 0 | 33 | |
| GSE47630 | UTP23 | 84294 | 24 | 0 | 16 | |
| GSE54993 | UTP23 | 84294 | 0 | 20 | 50 | |
| GSE54994 | UTP23 | 84294 | 37 | 1 | 15 | |
| GSE60625 | UTP23 | 84294 | 0 | 4 | 7 | |
| GSE74703 | UTP23 | 84294 | 19 | 0 | 17 | |
| GSE74704 | UTP23 | 84294 | 13 | 1 | 6 | |
| TCGA | UTP23 | 84294 | 63 | 2 | 31 |
Total number of gains: 241; Total number of losses: 30; Total Number of normals: 217.
Somatic mutations of UTP23:
Generating mutation plots.
Highly correlated genes for UTP23:
Showing top 20/1607 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UTP23 | CRTC2 | 0.821947 | 3 | 0 | 3 |
| UTP23 | ALKBH6 | 0.817061 | 3 | 0 | 3 |
| UTP23 | SH2B2 | 0.815082 | 3 | 0 | 3 |
| UTP23 | ZNF707 | 0.814001 | 3 | 0 | 3 |
| UTP23 | CARS2 | 0.811194 | 3 | 0 | 3 |
| UTP23 | NUCKS1 | 0.800592 | 4 | 0 | 3 |
| UTP23 | WDR54 | 0.793685 | 4 | 0 | 4 |
| UTP23 | ASH1L | 0.793096 | 3 | 0 | 3 |
| UTP23 | ZNF550 | 0.791704 | 3 | 0 | 3 |
| UTP23 | PGRMC1 | 0.790695 | 3 | 0 | 3 |
| UTP23 | GPR153 | 0.788148 | 3 | 0 | 3 |
| UTP23 | ZBED6 | 0.787355 | 3 | 0 | 3 |
| UTP23 | SLC22A5 | 0.786464 | 3 | 0 | 3 |
| UTP23 | INTS3 | 0.782679 | 3 | 0 | 3 |
| UTP23 | CHD7 | 0.781553 | 3 | 0 | 3 |
| UTP23 | DCUN1D2 | 0.777447 | 4 | 0 | 4 |
| UTP23 | SCARB1 | 0.776388 | 3 | 0 | 3 |
| UTP23 | LDB1 | 0.772271 | 3 | 0 | 3 |
| UTP23 | TYW5 | 0.772128 | 3 | 0 | 3 |
| UTP23 | SETD6 | 0.769996 | 3 | 0 | 3 |
For details and further investigation, click here
