| Full name: intermediate filament family orphan 1 | Alias Symbol: HOM-TES-103 | ||
| Type: protein-coding gene | Cytoband: 12p13.31 | ||
| Entrez ID: 25900 | HGNC ID: HGNC:24970 | Ensembl Gene: ENSG00000010295 | OMIM ID: 610495 |
| Drug and gene relationship at DGIdb | |||
Expression of IFFO1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IFFO1 | 25900 | 36030_at | -0.1680 | 0.7739 | |
| GSE20347 | IFFO1 | 25900 | 209721_s_at | 0.1150 | 0.3915 | |
| GSE23400 | IFFO1 | 25900 | 209721_s_at | -0.0501 | 0.3502 | |
| GSE26886 | IFFO1 | 25900 | 209721_s_at | -0.0398 | 0.8005 | |
| GSE29001 | IFFO1 | 25900 | 209721_s_at | 0.2707 | 0.2891 | |
| GSE38129 | IFFO1 | 25900 | 209721_s_at | -0.1856 | 0.1896 | |
| GSE45670 | IFFO1 | 25900 | 209721_s_at | -0.3515 | 0.0722 | |
| GSE53622 | IFFO1 | 25900 | 57933 | -0.1999 | 0.0011 | |
| GSE53624 | IFFO1 | 25900 | 57933 | -0.2962 | 0.0002 | |
| GSE63941 | IFFO1 | 25900 | 209721_s_at | -2.4825 | 0.0000 | |
| GSE77861 | IFFO1 | 25900 | 36030_at | 0.0482 | 0.6193 | |
| GSE97050 | IFFO1 | 25900 | A_23_P87742 | 0.0503 | 0.8725 | |
| SRP007169 | IFFO1 | 25900 | RNAseq | 2.2651 | 0.0028 | |
| SRP008496 | IFFO1 | 25900 | RNAseq | 2.2002 | 0.0003 | |
| SRP064894 | IFFO1 | 25900 | RNAseq | 0.6028 | 0.0351 | |
| SRP133303 | IFFO1 | 25900 | RNAseq | 0.0574 | 0.8357 | |
| SRP159526 | IFFO1 | 25900 | RNAseq | -0.4320 | 0.1233 | |
| SRP193095 | IFFO1 | 25900 | RNAseq | 0.8083 | 0.0002 | |
| SRP219564 | IFFO1 | 25900 | RNAseq | 0.2748 | 0.6222 | |
| TCGA | IFFO1 | 25900 | RNAseq | -0.1914 | 0.1403 |
Upregulated datasets: 2; Downregulated datasets: 1.
Survival by IFFO1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IFFO1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IFFO1 | 25900 | 9 | 4 | 17 | |
| GSE20123 | IFFO1 | 25900 | 9 | 4 | 17 | |
| GSE43470 | IFFO1 | 25900 | 8 | 3 | 32 | |
| GSE46452 | IFFO1 | 25900 | 10 | 1 | 48 | |
| GSE47630 | IFFO1 | 25900 | 12 | 2 | 26 | |
| GSE54993 | IFFO1 | 25900 | 1 | 10 | 59 | |
| GSE54994 | IFFO1 | 25900 | 10 | 2 | 41 | |
| GSE60625 | IFFO1 | 25900 | 0 | 1 | 10 | |
| GSE74703 | IFFO1 | 25900 | 7 | 2 | 27 | |
| GSE74704 | IFFO1 | 25900 | 5 | 3 | 12 | |
| TCGA | IFFO1 | 25900 | 40 | 6 | 50 |
Total number of gains: 111; Total number of losses: 38; Total Number of normals: 339.
Somatic mutations of IFFO1:
Generating mutation plots.
Highly correlated genes for IFFO1:
Showing top 20/370 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IFFO1 | IGF2 | 0.77231 | 3 | 0 | 3 |
| IFFO1 | MAGI1 | 0.759945 | 3 | 0 | 3 |
| IFFO1 | RSPH9 | 0.757491 | 4 | 0 | 4 |
| IFFO1 | DUSP8 | 0.747524 | 3 | 0 | 3 |
| IFFO1 | IL33 | 0.746486 | 4 | 0 | 4 |
| IFFO1 | FBN1 | 0.735752 | 6 | 0 | 5 |
| IFFO1 | KRTAP10-9 | 0.703826 | 3 | 0 | 3 |
| IFFO1 | KRTAP9-6 | 0.70377 | 3 | 0 | 3 |
| IFFO1 | C20orf194 | 0.701962 | 3 | 0 | 3 |
| IFFO1 | IQGAP2 | 0.70011 | 5 | 0 | 5 |
| IFFO1 | MMP14 | 0.699143 | 3 | 0 | 3 |
| IFFO1 | ANKRD44 | 0.694502 | 5 | 0 | 4 |
| IFFO1 | C11orf96 | 0.693879 | 4 | 0 | 3 |
| IFFO1 | ZEB2 | 0.691615 | 7 | 0 | 6 |
| IFFO1 | CACNA2D1 | 0.69029 | 4 | 0 | 4 |
| IFFO1 | DIXDC1 | 0.690258 | 6 | 0 | 6 |
| IFFO1 | MAGI2-AS3 | 0.688913 | 3 | 0 | 3 |
| IFFO1 | KIRREL3 | 0.686908 | 3 | 0 | 3 |
| IFFO1 | SH3KBP1 | 0.684735 | 4 | 0 | 4 |
| IFFO1 | ZNF608 | 0.683511 | 3 | 0 | 3 |
For details and further investigation, click here
