| Full name: DIX domain containing 1 | Alias Symbol: KIAA1735|Dixin | ||
| Type: protein-coding gene | Cytoband: 11q23.1 | ||
| Entrez ID: 85458 | HGNC ID: HGNC:23695 | Ensembl Gene: ENSG00000150764 | OMIM ID: 610493 |
| Drug and gene relationship at DGIdb | |||
Expression of DIXDC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DIXDC1 | 85458 | 214724_at | -1.4412 | 0.3318 | |
| GSE20347 | DIXDC1 | 85458 | 214724_at | -0.3536 | 0.2178 | |
| GSE23400 | DIXDC1 | 85458 | 214724_at | -0.4442 | 0.0080 | |
| GSE26886 | DIXDC1 | 85458 | 1558340_at | 0.1172 | 0.2953 | |
| GSE29001 | DIXDC1 | 85458 | 214724_at | -0.3214 | 0.1788 | |
| GSE38129 | DIXDC1 | 85458 | 214724_at | -1.0090 | 0.0072 | |
| GSE45670 | DIXDC1 | 85458 | 214724_at | -2.2982 | 0.0000 | |
| GSE53622 | DIXDC1 | 85458 | 61496 | -1.4289 | 0.0000 | |
| GSE53624 | DIXDC1 | 85458 | 61496 | -0.9448 | 0.0000 | |
| GSE63941 | DIXDC1 | 85458 | 214724_at | -4.5220 | 0.0001 | |
| GSE77861 | DIXDC1 | 85458 | 1558340_at | -0.0547 | 0.6001 | |
| GSE97050 | DIXDC1 | 85458 | A_33_P3399090 | -1.7520 | 0.0502 | |
| SRP007169 | DIXDC1 | 85458 | RNAseq | 1.3323 | 0.0038 | |
| SRP008496 | DIXDC1 | 85458 | RNAseq | 1.3645 | 0.0020 | |
| SRP064894 | DIXDC1 | 85458 | RNAseq | -0.1832 | 0.5815 | |
| SRP133303 | DIXDC1 | 85458 | RNAseq | -0.3248 | 0.4045 | |
| SRP159526 | DIXDC1 | 85458 | RNAseq | -0.7201 | 0.0268 | |
| SRP193095 | DIXDC1 | 85458 | RNAseq | -0.1478 | 0.5068 | |
| SRP219564 | DIXDC1 | 85458 | RNAseq | -0.5403 | 0.4773 | |
| TCGA | DIXDC1 | 85458 | RNAseq | -0.6870 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 4.
Survival by DIXDC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DIXDC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DIXDC1 | 85458 | 0 | 12 | 18 | |
| GSE20123 | DIXDC1 | 85458 | 0 | 12 | 18 | |
| GSE43470 | DIXDC1 | 85458 | 2 | 6 | 35 | |
| GSE46452 | DIXDC1 | 85458 | 3 | 26 | 30 | |
| GSE47630 | DIXDC1 | 85458 | 2 | 19 | 19 | |
| GSE54993 | DIXDC1 | 85458 | 10 | 0 | 60 | |
| GSE54994 | DIXDC1 | 85458 | 5 | 19 | 29 | |
| GSE60625 | DIXDC1 | 85458 | 0 | 3 | 8 | |
| GSE74703 | DIXDC1 | 85458 | 1 | 4 | 31 | |
| GSE74704 | DIXDC1 | 85458 | 0 | 8 | 12 | |
| TCGA | DIXDC1 | 85458 | 7 | 48 | 41 |
Total number of gains: 30; Total number of losses: 157; Total Number of normals: 301.
Somatic mutations of DIXDC1:
Generating mutation plots.
Highly correlated genes for DIXDC1:
Showing top 20/882 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DIXDC1 | FIBIN | 0.900029 | 4 | 0 | 4 |
| DIXDC1 | UBXN10 | 0.8816 | 3 | 0 | 3 |
| DIXDC1 | MSRB3 | 0.880929 | 6 | 0 | 6 |
| DIXDC1 | MRGPRF | 0.876617 | 6 | 0 | 6 |
| DIXDC1 | KANK2 | 0.875383 | 9 | 0 | 9 |
| DIXDC1 | DACT3 | 0.87472 | 5 | 0 | 5 |
| DIXDC1 | TNFSF12 | 0.867852 | 3 | 0 | 3 |
| DIXDC1 | LRRN4CL | 0.851212 | 6 | 0 | 6 |
| DIXDC1 | BHMT2 | 0.850576 | 9 | 0 | 9 |
| DIXDC1 | MGARP | 0.850345 | 3 | 0 | 3 |
| DIXDC1 | ZCCHC24 | 0.84569 | 9 | 0 | 9 |
| DIXDC1 | DCHS1 | 0.84391 | 6 | 0 | 6 |
| DIXDC1 | CLEC3B | 0.841675 | 3 | 0 | 3 |
| DIXDC1 | NEGR1 | 0.840939 | 6 | 0 | 6 |
| DIXDC1 | EBF1 | 0.83023 | 6 | 0 | 6 |
| DIXDC1 | LINC01279 | 0.821049 | 3 | 0 | 3 |
| DIXDC1 | DDR2 | 0.814352 | 9 | 0 | 8 |
| DIXDC1 | AOC3 | 0.81208 | 10 | 0 | 9 |
| DIXDC1 | SLIT2 | 0.810016 | 9 | 0 | 8 |
| DIXDC1 | RSPO3 | 0.808196 | 6 | 0 | 6 |
For details and further investigation, click here
