| Full name: inositol polyphosphate-5-phosphatase J | Alias Symbol: INPP5|PIPP | ||
| Type: protein-coding gene | Cytoband: 22q12.2 | ||
| Entrez ID: 27124 | HGNC ID: HGNC:8956 | Ensembl Gene: ENSG00000185133 | OMIM ID: 606481 |
| Drug and gene relationship at DGIdb | |||
Expression of INPP5J:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | INPP5J | 27124 | 213651_at | 0.0779 | 0.8068 | |
| GSE20347 | INPP5J | 27124 | 213651_at | -0.0707 | 0.4752 | |
| GSE23400 | INPP5J | 27124 | 213651_at | -0.2544 | 0.0000 | |
| GSE26886 | INPP5J | 27124 | 213651_at | 0.0136 | 0.9546 | |
| GSE29001 | INPP5J | 27124 | 213651_at | -0.3584 | 0.0461 | |
| GSE38129 | INPP5J | 27124 | 213651_at | -0.1786 | 0.0530 | |
| GSE45670 | INPP5J | 27124 | 213651_at | 0.1493 | 0.1731 | |
| GSE53622 | INPP5J | 27124 | 31498 | -0.2142 | 0.0083 | |
| GSE53624 | INPP5J | 27124 | 31498 | -0.1757 | 0.0952 | |
| GSE63941 | INPP5J | 27124 | 213651_at | 0.7874 | 0.0004 | |
| GSE77861 | INPP5J | 27124 | 213651_at | 0.1064 | 0.6558 | |
| GSE97050 | INPP5J | 27124 | A_24_P284805 | -0.0269 | 0.9668 | |
| SRP064894 | INPP5J | 27124 | RNAseq | 0.3058 | 0.3571 | |
| SRP133303 | INPP5J | 27124 | RNAseq | -0.6243 | 0.1037 | |
| SRP159526 | INPP5J | 27124 | RNAseq | 0.8129 | 0.0293 | |
| SRP219564 | INPP5J | 27124 | RNAseq | -0.2745 | 0.6154 | |
| TCGA | INPP5J | 27124 | RNAseq | -0.8963 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by INPP5J expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of INPP5J:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | INPP5J | 27124 | 4 | 5 | 21 | |
| GSE20123 | INPP5J | 27124 | 4 | 4 | 22 | |
| GSE43470 | INPP5J | 27124 | 4 | 5 | 34 | |
| GSE46452 | INPP5J | 27124 | 31 | 1 | 27 | |
| GSE47630 | INPP5J | 27124 | 8 | 5 | 27 | |
| GSE54993 | INPP5J | 27124 | 3 | 6 | 61 | |
| GSE54994 | INPP5J | 27124 | 12 | 7 | 34 | |
| GSE60625 | INPP5J | 27124 | 5 | 0 | 6 | |
| GSE74703 | INPP5J | 27124 | 4 | 5 | 27 | |
| GSE74704 | INPP5J | 27124 | 1 | 1 | 18 | |
| TCGA | INPP5J | 27124 | 27 | 15 | 54 |
Total number of gains: 103; Total number of losses: 54; Total Number of normals: 331.
Somatic mutations of INPP5J:
Generating mutation plots.
Highly correlated genes for INPP5J:
Showing top 20/585 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| INPP5J | MARK4 | 0.700237 | 5 | 0 | 5 |
| INPP5J | TESPA1 | 0.694788 | 3 | 0 | 3 |
| INPP5J | FAM131A | 0.693367 | 4 | 0 | 4 |
| INPP5J | CSNK1E | 0.688305 | 3 | 0 | 3 |
| INPP5J | TTC34 | 0.670936 | 3 | 0 | 3 |
| INPP5J | LINC00862 | 0.670385 | 3 | 0 | 3 |
| INPP5J | KIRREL2 | 0.670148 | 4 | 0 | 4 |
| INPP5J | LINC00930 | 0.665769 | 3 | 0 | 3 |
| INPP5J | TMEM151A | 0.658306 | 5 | 0 | 5 |
| INPP5J | ZNF169 | 0.647463 | 3 | 0 | 3 |
| INPP5J | ERICH4 | 0.636258 | 4 | 0 | 3 |
| INPP5J | MOSPD3 | 0.633581 | 4 | 0 | 3 |
| INPP5J | CACFD1 | 0.633414 | 5 | 0 | 4 |
| INPP5J | MYO15A | 0.631846 | 7 | 0 | 6 |
| INPP5J | GLI1 | 0.629613 | 3 | 0 | 3 |
| INPP5J | AKAP6 | 0.628707 | 4 | 0 | 3 |
| INPP5J | SHISA8 | 0.626399 | 4 | 0 | 4 |
| INPP5J | BLK | 0.625935 | 4 | 0 | 3 |
| INPP5J | CYP4A11 | 0.625668 | 6 | 0 | 6 |
| INPP5J | SHANK2-AS3 | 0.624187 | 3 | 0 | 3 |
For details and further investigation, click here
