| Full name: motile sperm domain containing 3 | Alias Symbol: CDS3|NET30 | ||
| Type: protein-coding gene | Cytoband: 7q22.1 | ||
| Entrez ID: 64598 | HGNC ID: HGNC:25078 | Ensembl Gene: ENSG00000106330 | OMIM ID: 609125 |
| Drug and gene relationship at DGIdb | |||
Expression of MOSPD3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MOSPD3 | 64598 | 219070_s_at | 0.2420 | 0.4933 | |
| GSE20347 | MOSPD3 | 64598 | 219070_s_at | -0.2637 | 0.0116 | |
| GSE23400 | MOSPD3 | 64598 | 219070_s_at | -0.2048 | 0.0001 | |
| GSE26886 | MOSPD3 | 64598 | 219070_s_at | 0.0990 | 0.5102 | |
| GSE29001 | MOSPD3 | 64598 | 219070_s_at | -0.3813 | 0.1302 | |
| GSE38129 | MOSPD3 | 64598 | 219070_s_at | -0.2023 | 0.0773 | |
| GSE45670 | MOSPD3 | 64598 | 219070_s_at | -0.1020 | 0.3246 | |
| GSE53622 | MOSPD3 | 64598 | 113958 | -0.5067 | 0.0000 | |
| GSE53624 | MOSPD3 | 64598 | 21337 | -0.7896 | 0.0000 | |
| GSE63941 | MOSPD3 | 64598 | 219070_s_at | 0.8231 | 0.0153 | |
| GSE77861 | MOSPD3 | 64598 | 219070_s_at | -0.3592 | 0.0305 | |
| GSE97050 | MOSPD3 | 64598 | A_23_P111492 | 0.0158 | 0.9516 | |
| SRP007169 | MOSPD3 | 64598 | RNAseq | -2.1089 | 0.0000 | |
| SRP008496 | MOSPD3 | 64598 | RNAseq | -2.0873 | 0.0000 | |
| SRP064894 | MOSPD3 | 64598 | RNAseq | -0.1703 | 0.5760 | |
| SRP133303 | MOSPD3 | 64598 | RNAseq | -0.6166 | 0.0011 | |
| SRP159526 | MOSPD3 | 64598 | RNAseq | -0.6896 | 0.0194 | |
| SRP193095 | MOSPD3 | 64598 | RNAseq | -0.6095 | 0.0003 | |
| SRP219564 | MOSPD3 | 64598 | RNAseq | -0.2146 | 0.5753 | |
| TCGA | MOSPD3 | 64598 | RNAseq | 0.0231 | 0.7468 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by MOSPD3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MOSPD3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MOSPD3 | 64598 | 13 | 0 | 17 | |
| GSE20123 | MOSPD3 | 64598 | 13 | 0 | 17 | |
| GSE43470 | MOSPD3 | 64598 | 7 | 2 | 34 | |
| GSE46452 | MOSPD3 | 64598 | 11 | 1 | 47 | |
| GSE47630 | MOSPD3 | 64598 | 7 | 3 | 30 | |
| GSE54993 | MOSPD3 | 64598 | 1 | 9 | 60 | |
| GSE54994 | MOSPD3 | 64598 | 16 | 3 | 34 | |
| GSE60625 | MOSPD3 | 64598 | 0 | 0 | 11 | |
| GSE74703 | MOSPD3 | 64598 | 7 | 1 | 28 | |
| GSE74704 | MOSPD3 | 64598 | 9 | 0 | 11 | |
| TCGA | MOSPD3 | 64598 | 53 | 6 | 37 |
Total number of gains: 137; Total number of losses: 25; Total Number of normals: 326.
Somatic mutations of MOSPD3:
Generating mutation plots.
Highly correlated genes for MOSPD3:
Showing top 20/916 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MOSPD3 | NLGN3 | 0.760415 | 4 | 0 | 4 |
| MOSPD3 | POLR2J | 0.755042 | 3 | 0 | 3 |
| MOSPD3 | RABEP2 | 0.753229 | 6 | 0 | 5 |
| MOSPD3 | TNK1 | 0.744005 | 5 | 0 | 5 |
| MOSPD3 | DDI2 | 0.732735 | 3 | 0 | 3 |
| MOSPD3 | SRP68 | 0.723793 | 3 | 0 | 3 |
| MOSPD3 | LTA4H | 0.717485 | 3 | 0 | 3 |
| MOSPD3 | SLC25A1 | 0.716655 | 3 | 0 | 3 |
| MOSPD3 | SH3BP2 | 0.708689 | 3 | 0 | 3 |
| MOSPD3 | CHID1 | 0.706969 | 3 | 0 | 3 |
| MOSPD3 | LRTOMT | 0.703529 | 4 | 0 | 3 |
| MOSPD3 | TSC22D4 | 0.693858 | 11 | 0 | 10 |
| MOSPD3 | IDH3G | 0.693819 | 3 | 0 | 3 |
| MOSPD3 | SCAND1 | 0.69031 | 3 | 0 | 3 |
| MOSPD3 | ESR2 | 0.689368 | 3 | 0 | 3 |
| MOSPD3 | RAB7A | 0.686769 | 3 | 0 | 3 |
| MOSPD3 | DLGAP1 | 0.684731 | 3 | 0 | 3 |
| MOSPD3 | STRADA | 0.681899 | 4 | 0 | 4 |
| MOSPD3 | SLC22A23 | 0.681294 | 3 | 0 | 3 |
| MOSPD3 | ABCD2 | 0.679039 | 3 | 0 | 3 |
For details and further investigation, click here
