| Full name: cytochrome P450 family 4 subfamily A member 11 | Alias Symbol: CYP4AII | ||
| Type: protein-coding gene | Cytoband: 1p33 | ||
| Entrez ID: 1579 | HGNC ID: HGNC:2642 | Ensembl Gene: ENSG00000187048 | OMIM ID: 601310 |
| Drug and gene relationship at DGIdb | |||
Expression of CYP4A11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CYP4A11 | 1579 | 211231_x_at | -0.1821 | 0.4974 | |
| GSE20347 | CYP4A11 | 1579 | 211231_x_at | 0.0166 | 0.9140 | |
| GSE23400 | CYP4A11 | 1579 | 211231_x_at | -0.1679 | 0.0000 | |
| GSE26886 | CYP4A11 | 1579 | 211231_x_at | -0.0124 | 0.9358 | |
| GSE29001 | CYP4A11 | 1579 | 211231_x_at | -0.1855 | 0.1488 | |
| GSE38129 | CYP4A11 | 1579 | 211231_x_at | -0.1732 | 0.1515 | |
| GSE45670 | CYP4A11 | 1579 | 211231_x_at | 0.0118 | 0.9400 | |
| GSE53622 | CYP4A11 | 1579 | 160343 | -0.3779 | 0.0025 | |
| GSE53624 | CYP4A11 | 1579 | 160343 | -0.5536 | 0.0000 | |
| GSE63941 | CYP4A11 | 1579 | 211231_x_at | 0.2799 | 0.1474 | |
| GSE77861 | CYP4A11 | 1579 | 211231_x_at | -0.0350 | 0.8219 | |
| GSE97050 | CYP4A11 | 1579 | A_24_P191013 | 0.0952 | 0.7307 | |
| SRP133303 | CYP4A11 | 1579 | RNAseq | -0.2781 | 0.0977 | |
| SRP159526 | CYP4A11 | 1579 | RNAseq | 0.1707 | 0.8194 | |
| SRP193095 | CYP4A11 | 1579 | RNAseq | 0.0223 | 0.9053 | |
| SRP219564 | CYP4A11 | 1579 | RNAseq | 0.6905 | 0.2625 | |
| TCGA | CYP4A11 | 1579 | RNAseq | -2.3658 | 0.0053 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by CYP4A11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CYP4A11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CYP4A11 | 1579 | 4 | 3 | 23 | |
| GSE20123 | CYP4A11 | 1579 | 4 | 2 | 24 | |
| GSE43470 | CYP4A11 | 1579 | 5 | 1 | 37 | |
| GSE46452 | CYP4A11 | 1579 | 2 | 1 | 56 | |
| GSE47630 | CYP4A11 | 1579 | 8 | 4 | 28 | |
| GSE54993 | CYP4A11 | 1579 | 0 | 1 | 69 | |
| GSE54994 | CYP4A11 | 1579 | 11 | 2 | 40 | |
| GSE60625 | CYP4A11 | 1579 | 0 | 0 | 11 | |
| GSE74703 | CYP4A11 | 1579 | 4 | 1 | 31 | |
| GSE74704 | CYP4A11 | 1579 | 2 | 0 | 18 | |
| TCGA | CYP4A11 | 1579 | 10 | 17 | 69 |
Total number of gains: 50; Total number of losses: 32; Total Number of normals: 406.
Somatic mutations of CYP4A11:
Generating mutation plots.
Highly correlated genes for CYP4A11:
Showing top 20/989 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CYP4A11 | VSTM2A | 0.773399 | 3 | 0 | 3 |
| CYP4A11 | CCDC157 | 0.71609 | 3 | 0 | 3 |
| CYP4A11 | KHDRBS2 | 0.714779 | 4 | 0 | 4 |
| CYP4A11 | PDE6G | 0.707802 | 7 | 0 | 7 |
| CYP4A11 | KLF15 | 0.706878 | 6 | 0 | 6 |
| CYP4A11 | MUC8 | 0.704619 | 6 | 0 | 5 |
| CYP4A11 | RNF17 | 0.702088 | 5 | 0 | 5 |
| CYP4A11 | ADM2 | 0.692967 | 6 | 0 | 6 |
| CYP4A11 | KIR3DL3 | 0.690545 | 7 | 0 | 7 |
| CYP4A11 | UMOD | 0.689906 | 6 | 0 | 5 |
| CYP4A11 | SPINT3 | 0.687391 | 6 | 0 | 6 |
| CYP4A11 | CNR2 | 0.685971 | 8 | 0 | 8 |
| CYP4A11 | FSHR | 0.685421 | 6 | 0 | 6 |
| CYP4A11 | PF4 | 0.68477 | 5 | 0 | 4 |
| CYP4A11 | KIR3DS1 | 0.683832 | 4 | 0 | 4 |
| CYP4A11 | CACFD1 | 0.682402 | 5 | 0 | 5 |
| CYP4A11 | SYT13 | 0.682017 | 4 | 0 | 3 |
| CYP4A11 | MIR4755 | 0.681661 | 3 | 0 | 3 |
| CYP4A11 | ACR | 0.681601 | 7 | 0 | 7 |
| CYP4A11 | KIR2DS4 | 0.680895 | 5 | 0 | 5 |
For details and further investigation, click here
