| Full name: casein kinase 1 epsilon | Alias Symbol: HCKIE|CKIE|CKIepsilon | ||
| Type: protein-coding gene | Cytoband: 22q13.1 | ||
| Entrez ID: 1454 | HGNC ID: HGNC:2453 | Ensembl Gene: ENSG00000213923 | OMIM ID: 600863 |
| Drug and gene relationship at DGIdb | |||
CSNK1E involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04068 | FoxO signaling pathway | |
| hsa04340 | Hedgehog signaling pathway | |
| hsa04390 | Hippo signaling pathway | |
| hsa04710 | Circadian rhythm |
Expression of CSNK1E:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CSNK1E | 1454 | 226858_at | 0.4853 | 0.3484 | |
| GSE20347 | CSNK1E | 1454 | 222015_at | -0.3626 | 0.0013 | |
| GSE23400 | CSNK1E | 1454 | 222015_at | -0.3009 | 0.0000 | |
| GSE26886 | CSNK1E | 1454 | 226858_at | 0.4068 | 0.3081 | |
| GSE29001 | CSNK1E | 1454 | 222015_at | -0.4992 | 0.0365 | |
| GSE38129 | CSNK1E | 1454 | 222015_at | -0.2430 | 0.0137 | |
| GSE45670 | CSNK1E | 1454 | 226858_at | 0.3287 | 0.1363 | |
| GSE53622 | CSNK1E | 1454 | 127936 | 0.4689 | 0.0000 | |
| GSE53624 | CSNK1E | 1454 | 127936 | 0.5130 | 0.0000 | |
| GSE63941 | CSNK1E | 1454 | 226858_at | -0.4957 | 0.4127 | |
| GSE77861 | CSNK1E | 1454 | 226858_at | 0.2311 | 0.4115 | |
| GSE97050 | CSNK1E | 1454 | A_33_P3265180 | 0.0932 | 0.7370 | |
| SRP007169 | CSNK1E | 1454 | RNAseq | -1.0536 | 0.0693 | |
| SRP008496 | CSNK1E | 1454 | RNAseq | -0.8237 | 0.0090 | |
| SRP064894 | CSNK1E | 1454 | RNAseq | -0.0327 | 0.8767 | |
| SRP133303 | CSNK1E | 1454 | RNAseq | 0.2508 | 0.1556 | |
| SRP159526 | CSNK1E | 1454 | RNAseq | 0.3490 | 0.2339 | |
| SRP193095 | CSNK1E | 1454 | RNAseq | 0.1700 | 0.3785 | |
| SRP219564 | CSNK1E | 1454 | RNAseq | 0.2425 | 0.4943 | |
| TCGA | CSNK1E | 1454 | RNAseq | 0.1673 | 0.0003 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CSNK1E expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CSNK1E:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CSNK1E | 1454 | 6 | 5 | 19 | |
| GSE20123 | CSNK1E | 1454 | 6 | 4 | 20 | |
| GSE43470 | CSNK1E | 1454 | 5 | 5 | 33 | |
| GSE46452 | CSNK1E | 1454 | 32 | 2 | 25 | |
| GSE47630 | CSNK1E | 1454 | 9 | 4 | 27 | |
| GSE54993 | CSNK1E | 1454 | 3 | 6 | 61 | |
| GSE54994 | CSNK1E | 1454 | 9 | 7 | 37 | |
| GSE60625 | CSNK1E | 1454 | 5 | 0 | 6 | |
| GSE74703 | CSNK1E | 1454 | 5 | 4 | 27 | |
| GSE74704 | CSNK1E | 1454 | 3 | 2 | 15 | |
| TCGA | CSNK1E | 1454 | 28 | 15 | 53 |
Total number of gains: 111; Total number of losses: 54; Total Number of normals: 323.
Somatic mutations of CSNK1E:
Generating mutation plots.
Highly correlated genes for CSNK1E:
Showing top 20/154 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CSNK1E | LIPE | 0.734277 | 3 | 0 | 3 |
| CSNK1E | INPP5J | 0.688305 | 3 | 0 | 3 |
| CSNK1E | PTPRH | 0.663447 | 3 | 0 | 3 |
| CSNK1E | GALR3 | 0.643853 | 4 | 0 | 4 |
| CSNK1E | MAP6D1 | 0.6418 | 4 | 0 | 3 |
| CSNK1E | NAV1 | 0.637053 | 3 | 0 | 3 |
| CSNK1E | IGF2BP1 | 0.636233 | 3 | 0 | 3 |
| CSNK1E | PADI1 | 0.633221 | 4 | 0 | 4 |
| CSNK1E | FMNL1 | 0.630484 | 3 | 0 | 3 |
| CSNK1E | XPR1 | 0.621602 | 4 | 0 | 4 |
| CSNK1E | EIF1AD | 0.620673 | 3 | 0 | 3 |
| CSNK1E | APOA4 | 0.620182 | 6 | 0 | 4 |
| CSNK1E | DSCAM | 0.615212 | 3 | 0 | 3 |
| CSNK1E | BCL2L1 | 0.61324 | 3 | 0 | 3 |
| CSNK1E | CDCA7L | 0.610065 | 4 | 0 | 3 |
| CSNK1E | TRPV6 | 0.604963 | 3 | 0 | 3 |
| CSNK1E | IL24 | 0.604702 | 3 | 0 | 3 |
| CSNK1E | GFER | 0.60039 | 4 | 0 | 3 |
| CSNK1E | REG3A | 0.599788 | 3 | 0 | 3 |
| CSNK1E | SLC13A3 | 0.596662 | 5 | 0 | 3 |
For details and further investigation, click here
