| Full name: corticotropin releasing hormone receptor 2 | Alias Symbol: CRF2|CRF-RB|HM-CRF | ||
| Type: protein-coding gene | Cytoband: 7p14.3 | ||
| Entrez ID: 1395 | HGNC ID: HGNC:2358 | Ensembl Gene: ENSG00000106113 | OMIM ID: 602034 |
| Drug and gene relationship at DGIdb | |||
Expression of CRHR2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CRHR2 | 1395 | 207897_at | 0.0025 | 0.9957 | |
| GSE20347 | CRHR2 | 1395 | 207897_at | -0.0523 | 0.7320 | |
| GSE23400 | CRHR2 | 1395 | 207897_at | -0.0947 | 0.0592 | |
| GSE26886 | CRHR2 | 1395 | 207897_at | -0.1801 | 0.1459 | |
| GSE29001 | CRHR2 | 1395 | 207897_at | -0.3612 | 0.0228 | |
| GSE38129 | CRHR2 | 1395 | 207897_at | -0.1588 | 0.2118 | |
| GSE45670 | CRHR2 | 1395 | 207897_at | 0.0182 | 0.8890 | |
| GSE53622 | CRHR2 | 1395 | 78993 | -0.2506 | 0.0154 | |
| GSE53624 | CRHR2 | 1395 | 78993 | -0.1434 | 0.3513 | |
| GSE63941 | CRHR2 | 1395 | 207897_at | -0.1161 | 0.4010 | |
| GSE77861 | CRHR2 | 1395 | 207897_at | -0.1662 | 0.1722 | |
| SRP133303 | CRHR2 | 1395 | RNAseq | -0.5628 | 0.0990 | |
| SRP219564 | CRHR2 | 1395 | RNAseq | -0.4447 | 0.5086 | |
| TCGA | CRHR2 | 1395 | RNAseq | 0.0311 | 0.9666 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CRHR2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CRHR2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CRHR2 | 1395 | 15 | 0 | 15 | |
| GSE20123 | CRHR2 | 1395 | 15 | 0 | 15 | |
| GSE43470 | CRHR2 | 1395 | 4 | 0 | 39 | |
| GSE46452 | CRHR2 | 1395 | 11 | 1 | 47 | |
| GSE47630 | CRHR2 | 1395 | 8 | 1 | 31 | |
| GSE54993 | CRHR2 | 1395 | 0 | 6 | 64 | |
| GSE54994 | CRHR2 | 1395 | 19 | 3 | 31 | |
| GSE60625 | CRHR2 | 1395 | 0 | 0 | 11 | |
| GSE74703 | CRHR2 | 1395 | 4 | 0 | 32 | |
| GSE74704 | CRHR2 | 1395 | 9 | 0 | 11 | |
| TCGA | CRHR2 | 1395 | 55 | 7 | 34 |
Total number of gains: 140; Total number of losses: 18; Total Number of normals: 330.
Somatic mutations of CRHR2:
Generating mutation plots.
Highly correlated genes for CRHR2:
Showing top 20/1020 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CRHR2 | CAMK2B | 0.750406 | 6 | 0 | 6 |
| CRHR2 | MUC5AC | 0.74662 | 4 | 0 | 4 |
| CRHR2 | KCNJ10 | 0.746492 | 4 | 0 | 4 |
| CRHR2 | ZNF835 | 0.738742 | 3 | 0 | 3 |
| CRHR2 | FBP2 | 0.738507 | 4 | 0 | 4 |
| CRHR2 | HHLA1 | 0.733231 | 4 | 0 | 4 |
| CRHR2 | PSG9 | 0.731133 | 3 | 0 | 3 |
| CRHR2 | KIR2DS2 | 0.730043 | 6 | 0 | 6 |
| CRHR2 | KIR2DS5 | 0.729611 | 6 | 0 | 5 |
| CRHR2 | GH2 | 0.729025 | 4 | 0 | 3 |
| CRHR2 | PRR34 | 0.726654 | 5 | 0 | 5 |
| CRHR2 | CGA | 0.724757 | 6 | 0 | 5 |
| CRHR2 | FGF16 | 0.724379 | 4 | 0 | 4 |
| CRHR2 | USP2 | 0.724299 | 4 | 0 | 4 |
| CRHR2 | NR6A1 | 0.721719 | 4 | 0 | 4 |
| CRHR2 | TM6SF2 | 0.720191 | 3 | 0 | 3 |
| CRHR2 | TCL6 | 0.718401 | 4 | 0 | 4 |
| CRHR2 | CADPS | 0.716806 | 3 | 0 | 3 |
| CRHR2 | ENTPD2 | 0.715894 | 4 | 0 | 4 |
| CRHR2 | NTSR2 | 0.715838 | 4 | 0 | 4 |
For details and further investigation, click here
