| Full name: autophagy related 10 | Alias Symbol: DKFZP586I0418|FLJ13954 | ||
| Type: protein-coding gene | Cytoband: 5q14.1-q14.2 | ||
| Entrez ID: 83734 | HGNC ID: HGNC:20315 | Ensembl Gene: ENSG00000152348 | OMIM ID: 610800 |
| Drug and gene relationship at DGIdb | |||
Expression of ATG10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ATG10 | 83734 | 223677_at | -0.1277 | 0.8823 | |
| GSE20347 | ATG10 | 83734 | 207774_at | 0.1222 | 0.2303 | |
| GSE23400 | ATG10 | 83734 | 207774_at | -0.1303 | 0.0075 | |
| GSE26886 | ATG10 | 83734 | 223677_at | 1.0017 | 0.0001 | |
| GSE29001 | ATG10 | 83734 | 207774_at | -0.0941 | 0.6749 | |
| GSE38129 | ATG10 | 83734 | 207774_at | -0.0048 | 0.9606 | |
| GSE45670 | ATG10 | 83734 | 223677_at | 0.1452 | 0.4089 | |
| GSE53622 | ATG10 | 83734 | 63045 | -0.0071 | 0.9367 | |
| GSE53624 | ATG10 | 83734 | 63045 | -0.2782 | 0.0008 | |
| GSE63941 | ATG10 | 83734 | 223677_at | -0.1155 | 0.8429 | |
| GSE77861 | ATG10 | 83734 | 207774_at | -0.0929 | 0.3706 | |
| GSE97050 | ATG10 | 83734 | A_24_P370471 | -0.1123 | 0.7085 | |
| SRP007169 | ATG10 | 83734 | RNAseq | -0.7545 | 0.0908 | |
| SRP064894 | ATG10 | 83734 | RNAseq | -0.1979 | 0.1646 | |
| SRP133303 | ATG10 | 83734 | RNAseq | 0.1564 | 0.5013 | |
| SRP159526 | ATG10 | 83734 | RNAseq | -0.3788 | 0.2230 | |
| SRP193095 | ATG10 | 83734 | RNAseq | -0.3919 | 0.0001 | |
| SRP219564 | ATG10 | 83734 | RNAseq | -0.3914 | 0.1405 | |
| TCGA | ATG10 | 83734 | RNAseq | 0.0129 | 0.8814 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ATG10 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ATG10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ATG10 | 83734 | 1 | 13 | 16 | |
| GSE20123 | ATG10 | 83734 | 1 | 13 | 16 | |
| GSE43470 | ATG10 | 83734 | 2 | 11 | 30 | |
| GSE46452 | ATG10 | 83734 | 0 | 28 | 31 | |
| GSE47630 | ATG10 | 83734 | 1 | 19 | 20 | |
| GSE54993 | ATG10 | 83734 | 8 | 1 | 61 | |
| GSE54994 | ATG10 | 83734 | 2 | 18 | 33 | |
| GSE60625 | ATG10 | 83734 | 0 | 0 | 11 | |
| GSE74703 | ATG10 | 83734 | 1 | 7 | 28 | |
| GSE74704 | ATG10 | 83734 | 1 | 6 | 13 | |
| TCGA | ATG10 | 83734 | 5 | 49 | 42 |
Total number of gains: 22; Total number of losses: 165; Total Number of normals: 301.
Somatic mutations of ATG10:
Generating mutation plots.
Highly correlated genes for ATG10:
Showing top 20/439 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ATG10 | PIGX | 0.884664 | 3 | 0 | 3 |
| ATG10 | IL17RD | 0.843951 | 3 | 0 | 3 |
| ATG10 | BSN | 0.801567 | 3 | 0 | 3 |
| ATG10 | ZNF432 | 0.775975 | 3 | 0 | 3 |
| ATG10 | OCIAD1 | 0.773509 | 4 | 0 | 4 |
| ATG10 | ADAMTS12 | 0.748337 | 4 | 0 | 4 |
| ATG10 | CHAT | 0.746986 | 4 | 0 | 4 |
| ATG10 | PSG9 | 0.745091 | 3 | 0 | 3 |
| ATG10 | DOCK5 | 0.745033 | 3 | 0 | 3 |
| ATG10 | NTNG1 | 0.744155 | 4 | 0 | 4 |
| ATG10 | RUNX2 | 0.743342 | 5 | 0 | 5 |
| ATG10 | PRPS1L1 | 0.742362 | 5 | 0 | 5 |
| ATG10 | CGA | 0.739273 | 5 | 0 | 4 |
| ATG10 | KCNJ10 | 0.738957 | 6 | 0 | 5 |
| ATG10 | AKAP6 | 0.737421 | 5 | 0 | 5 |
| ATG10 | RAB8B | 0.73447 | 3 | 0 | 3 |
| ATG10 | GP2 | 0.733795 | 4 | 0 | 4 |
| ATG10 | RFPL2 | 0.73309 | 5 | 0 | 4 |
| ATG10 | MTRF1L | 0.730951 | 5 | 0 | 5 |
| ATG10 | SMIM2 | 0.729478 | 3 | 0 | 3 |
For details and further investigation, click here
