| Full name: oligophrenin 1 | Alias Symbol: OPN1|ARHGAP41 | ||
| Type: protein-coding gene | Cytoband: Xq12 | ||
| Entrez ID: 4983 | HGNC ID: HGNC:8148 | Ensembl Gene: ENSG00000079482 | OMIM ID: 300127 |
| Drug and gene relationship at DGIdb | |||
Expression of OPHN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OPHN1 | 4983 | 206323_x_at | -0.2104 | 0.4527 | |
| GSE20347 | OPHN1 | 4983 | 206323_x_at | 0.0985 | 0.6005 | |
| GSE23400 | OPHN1 | 4983 | 206323_x_at | -0.1281 | 0.0973 | |
| GSE26886 | OPHN1 | 4983 | 206323_x_at | -0.6203 | 0.0000 | |
| GSE29001 | OPHN1 | 4983 | 206323_x_at | -0.4018 | 0.0599 | |
| GSE38129 | OPHN1 | 4983 | 206323_x_at | -0.2575 | 0.3602 | |
| GSE45670 | OPHN1 | 4983 | 206323_x_at | -0.1196 | 0.3421 | |
| GSE53622 | OPHN1 | 4983 | 81807 | -0.4222 | 0.0001 | |
| GSE53624 | OPHN1 | 4983 | 81807 | -0.3387 | 0.0001 | |
| GSE63941 | OPHN1 | 4983 | 206323_x_at | 1.1167 | 0.0001 | |
| GSE77861 | OPHN1 | 4983 | 206323_x_at | -0.6928 | 0.0018 | |
| GSE97050 | OPHN1 | 4983 | A_33_P3307735 | -0.3943 | 0.2102 | |
| SRP007169 | OPHN1 | 4983 | RNAseq | 0.9776 | 0.0083 | |
| SRP008496 | OPHN1 | 4983 | RNAseq | 1.1964 | 0.0000 | |
| SRP064894 | OPHN1 | 4983 | RNAseq | 0.6434 | 0.0083 | |
| SRP133303 | OPHN1 | 4983 | RNAseq | 0.0720 | 0.5986 | |
| SRP159526 | OPHN1 | 4983 | RNAseq | 0.9625 | 0.0003 | |
| SRP193095 | OPHN1 | 4983 | RNAseq | 0.2696 | 0.0224 | |
| SRP219564 | OPHN1 | 4983 | RNAseq | 0.4673 | 0.1741 | |
| TCGA | OPHN1 | 4983 | RNAseq | -0.2411 | 0.0040 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by OPHN1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OPHN1:
No record found for this gene.
Somatic mutations of OPHN1:
Generating mutation plots.
Highly correlated genes for OPHN1:
Showing top 20/1214 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OPHN1 | STRBP | 0.846405 | 3 | 0 | 3 |
| OPHN1 | DNAH3 | 0.841597 | 7 | 0 | 7 |
| OPHN1 | OAT | 0.80259 | 3 | 0 | 3 |
| OPHN1 | E2F4 | 0.798925 | 7 | 0 | 7 |
| OPHN1 | GTF2H3 | 0.793749 | 3 | 0 | 3 |
| OPHN1 | MBNL3 | 0.780886 | 5 | 0 | 5 |
| OPHN1 | SFTA2 | 0.769644 | 4 | 0 | 4 |
| OPHN1 | PAIP2 | 0.768587 | 3 | 0 | 3 |
| OPHN1 | RAB27A | 0.767228 | 4 | 0 | 4 |
| OPHN1 | KRCC1 | 0.766493 | 4 | 0 | 4 |
| OPHN1 | KRT78 | 0.763873 | 4 | 0 | 4 |
| OPHN1 | LAMTOR3 | 0.758871 | 4 | 0 | 4 |
| OPHN1 | CXCL17 | 0.758013 | 4 | 0 | 4 |
| OPHN1 | FRAS1 | 0.756407 | 5 | 0 | 5 |
| OPHN1 | ATG9B | 0.75626 | 4 | 0 | 4 |
| OPHN1 | INTS6 | 0.755337 | 3 | 0 | 3 |
| OPHN1 | CLN8 | 0.752433 | 3 | 0 | 3 |
| OPHN1 | SNORA68 | 0.75158 | 4 | 0 | 4 |
| OPHN1 | ZNF460 | 0.751144 | 5 | 0 | 5 |
| OPHN1 | DENND2D | 0.746492 | 5 | 0 | 4 |
For details and further investigation, click here
