TCP10L

 

Full name: t-complex 10 like Alias Symbol: PRED77
Type: protein-coding gene Cytoband: 21q22.11
Entrez ID: 140290 HGNC ID: HGNC:11657 Ensembl Gene: ENSG00000242220 OMIM ID: 608365
Drug and gene relationship at DGIdb

 

Expression of TCP10L:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TCP10L 140290 230394_at 0.0109 0.9700
GSE20347 TCP10L 140290 220826_at -0.0737 0.5633
GSE23400 TCP10L 140290 220826_at -0.2510 0.0000
GSE26886 TCP10L 140290 230394_at -0.0146 0.9245
GSE29001 TCP10L 140290 220826_at -0.0286 0.8737
GSE38129 TCP10L 140290 220826_at -0.2029 0.0587
GSE45670 TCP10L 140290 230394_at -0.0085 0.9552
GSE53622 TCP10L 140290 23268 0.0208 0.8417
GSE53624 TCP10L 140290 23268 0.1272 0.1815
GSE63941 TCP10L 140290 220826_at 0.2037 0.1966
GSE77861 TCP10L 140290 220826_at -0.1272 0.1948
TCGA TCP10L 140290 RNAseq 0.5412 0.2274

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by TCP10L expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of TCP10L:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TCP10L 140290 2 7 21
GSE20123 TCP10L 140290 2 8 20
GSE43470 TCP10L 140290 3 7 33
GSE46452 TCP10L 140290 1 21 37
GSE47630 TCP10L 140290 6 17 17
GSE54993 TCP10L 140290 9 1 60
GSE54994 TCP10L 140290 1 8 44
GSE60625 TCP10L 140290 0 0 11
GSE74703 TCP10L 140290 3 5 28
GSE74704 TCP10L 140290 1 4 15
TCGA TCP10L 140290 9 36 51

Total number of gains: 37; Total number of losses: 114; Total Number of normals: 337.  


 

Somatic mutations of TCP10L:

 

Generating mutation plots.

 

Highly correlated genes for TCP10L:

 

Showing top 20/1021 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TCP10LIL17A0.75258505
TCP10LOR10J10.7466404
TCP10LHHLA10.737766404
TCP10LTUB0.737395404
TCP10LKCNJ100.734699404
TCP10LMTAP0.727822404
TCP10LPRL0.72745505
TCP10LAKAP60.72541404
TCP10LHECW10.723043505
TCP10LTRPM30.722388404
TCP10LKSR10.718119404
TCP10LCHST40.717273505
TCP10LMVK0.715754404
TCP10LAMELY0.712653404
TCP10LCCDC300.711202505
TCP10LIL1RAPL20.710849505
TCP10LJAK30.710308505
TCP10LARMC40.707912404
TCP10LPPM1E0.707078303
TCP10LNXPE40.706704404

For details and further investigation, click here