| Full name: ret finger protein like 3 | Alias Symbol: RNF120 | ||
| Type: protein-coding gene | Cytoband: 22q12.3 | ||
| Entrez ID: 10738 | HGNC ID: HGNC:9980 | Ensembl Gene: ENSG00000128276 | OMIM ID: 605970 |
| Drug and gene relationship at DGIdb | |||
Expression of RFPL3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RFPL3 | 10738 | 207936_x_at | 0.2112 | 0.2970 | |
| GSE20347 | RFPL3 | 10738 | 207936_x_at | 0.0406 | 0.7287 | |
| GSE23400 | RFPL3 | 10738 | 207936_x_at | -0.0775 | 0.1525 | |
| GSE26886 | RFPL3 | 10738 | 207936_x_at | -0.1067 | 0.4004 | |
| GSE29001 | RFPL3 | 10738 | 207936_x_at | -0.1681 | 0.3762 | |
| GSE38129 | RFPL3 | 10738 | 207936_x_at | -0.0796 | 0.4753 | |
| GSE45670 | RFPL3 | 10738 | 207936_x_at | 0.2162 | 0.1187 | |
| GSE53622 | RFPL3 | 10738 | 88591 | 0.1129 | 0.3282 | |
| GSE53624 | RFPL3 | 10738 | 88591 | 0.3787 | 0.0001 | |
| GSE63941 | RFPL3 | 10738 | 207936_x_at | 0.2049 | 0.2542 | |
| GSE77861 | RFPL3 | 10738 | 207936_x_at | 0.0492 | 0.7139 | |
| TCGA | RFPL3 | 10738 | RNAseq | 0.5727 | 0.5438 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RFPL3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RFPL3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RFPL3 | 10738 | 4 | 5 | 21 | |
| GSE20123 | RFPL3 | 10738 | 4 | 4 | 22 | |
| GSE43470 | RFPL3 | 10738 | 4 | 5 | 34 | |
| GSE46452 | RFPL3 | 10738 | 31 | 1 | 27 | |
| GSE47630 | RFPL3 | 10738 | 8 | 5 | 27 | |
| GSE54993 | RFPL3 | 10738 | 3 | 6 | 61 | |
| GSE54994 | RFPL3 | 10738 | 10 | 9 | 34 | |
| GSE60625 | RFPL3 | 10738 | 5 | 0 | 6 | |
| GSE74703 | RFPL3 | 10738 | 4 | 5 | 27 | |
| GSE74704 | RFPL3 | 10738 | 1 | 1 | 18 | |
| TCGA | RFPL3 | 10738 | 27 | 15 | 54 |
Total number of gains: 101; Total number of losses: 56; Total Number of normals: 331.
Somatic mutations of RFPL3:
Generating mutation plots.
Highly correlated genes for RFPL3:
Showing top 20/703 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RFPL3 | ZNF835 | 0.738458 | 3 | 0 | 3 |
| RFPL3 | KCNJ10 | 0.737967 | 4 | 0 | 4 |
| RFPL3 | ERN1 | 0.728819 | 3 | 0 | 3 |
| RFPL3 | PHLDB1 | 0.725428 | 4 | 0 | 4 |
| RFPL3 | MEFV | 0.724389 | 3 | 0 | 3 |
| RFPL3 | BUB1 | 0.722317 | 3 | 0 | 3 |
| RFPL3 | TP53I11 | 0.715864 | 3 | 0 | 3 |
| RFPL3 | IL1RAPL2 | 0.712212 | 4 | 0 | 4 |
| RFPL3 | GABRR2 | 0.706418 | 4 | 0 | 4 |
| RFPL3 | TCP10L | 0.706132 | 4 | 0 | 4 |
| RFPL3 | CTAGE1 | 0.705389 | 4 | 0 | 4 |
| RFPL3 | OPHN1 | 0.70345 | 3 | 0 | 3 |
| RFPL3 | KRT76 | 0.702923 | 4 | 0 | 4 |
| RFPL3 | KIR3DL3 | 0.696073 | 5 | 0 | 5 |
| RFPL3 | SLC17A3 | 0.695674 | 5 | 0 | 5 |
| RFPL3 | AMHR2 | 0.690874 | 4 | 0 | 4 |
| RFPL3 | ZNF507 | 0.690694 | 4 | 0 | 4 |
| RFPL3 | SLC5A5 | 0.690586 | 5 | 0 | 5 |
| RFPL3 | ADAMTS12 | 0.689641 | 5 | 0 | 5 |
| RFPL3 | PROZ | 0.688859 | 4 | 0 | 4 |
For details and further investigation, click here
