| Full name: potassium two pore domain channel subfamily K member 9 | Alias Symbol: K2p9.1|TASK3|TASK-3 | ||
| Type: protein-coding gene | Cytoband: 8q24.3 | ||
| Entrez ID: 51305 | HGNC ID: HGNC:6283 | Ensembl Gene: ENSG00000169427 | OMIM ID: 605874 |
| Drug and gene relationship at DGIdb | |||
KCNK9 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04925 | Aldosterone synthesis and secretion |
Expression of KCNK9:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KCNK9 | 51305 | 224072_s_at | -0.1123 | 0.7012 | |
| GSE26886 | KCNK9 | 51305 | 238870_at | 0.3589 | 0.0425 | |
| GSE45670 | KCNK9 | 51305 | 238870_at | 0.4091 | 0.1665 | |
| GSE53622 | KCNK9 | 51305 | 40903 | 0.3973 | 0.0000 | |
| GSE53624 | KCNK9 | 51305 | 40903 | 0.3924 | 0.0000 | |
| GSE63941 | KCNK9 | 51305 | 238870_at | 0.5542 | 0.1832 | |
| GSE77861 | KCNK9 | 51305 | 238870_at | -0.2207 | 0.2001 | |
| GSE97050 | KCNK9 | 51305 | A_23_P111978 | 0.0603 | 0.8987 | |
| TCGA | KCNK9 | 51305 | RNAseq | 0.9075 | 0.0641 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by KCNK9 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KCNK9:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KCNK9 | 51305 | 16 | 0 | 14 | |
| GSE20123 | KCNK9 | 51305 | 16 | 0 | 14 | |
| GSE43470 | KCNK9 | 51305 | 22 | 1 | 20 | |
| GSE46452 | KCNK9 | 51305 | 27 | 0 | 32 | |
| GSE47630 | KCNK9 | 51305 | 24 | 0 | 16 | |
| GSE54993 | KCNK9 | 51305 | 0 | 25 | 45 | |
| GSE54994 | KCNK9 | 51305 | 39 | 1 | 13 | |
| GSE60625 | KCNK9 | 51305 | 3 | 4 | 4 | |
| GSE74703 | KCNK9 | 51305 | 19 | 0 | 17 | |
| GSE74704 | KCNK9 | 51305 | 10 | 0 | 10 | |
| TCGA | KCNK9 | 51305 | 64 | 2 | 30 |
Total number of gains: 240; Total number of losses: 33; Total Number of normals: 215.
Somatic mutations of KCNK9:
Generating mutation plots.
Highly correlated genes for KCNK9:
Showing top 20/460 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KCNK9 | SORCS3 | 0.82618 | 3 | 0 | 3 |
| KCNK9 | RAB44 | 0.811384 | 3 | 0 | 3 |
| KCNK9 | OR2T1 | 0.80785 | 3 | 0 | 3 |
| KCNK9 | TPH2 | 0.796845 | 3 | 0 | 3 |
| KCNK9 | TTLL9 | 0.789274 | 3 | 0 | 3 |
| KCNK9 | MRGPRG | 0.781573 | 3 | 0 | 3 |
| KCNK9 | MS4A18 | 0.781063 | 3 | 0 | 3 |
| KCNK9 | FOXE3 | 0.776828 | 3 | 0 | 3 |
| KCNK9 | FFAR1 | 0.77652 | 5 | 0 | 5 |
| KCNK9 | BLACE | 0.775475 | 3 | 0 | 3 |
| KCNK9 | DCDC1 | 0.772045 | 3 | 0 | 3 |
| KCNK9 | OR2A5 | 0.766124 | 3 | 0 | 3 |
| KCNK9 | ZNF236 | 0.765601 | 3 | 0 | 3 |
| KCNK9 | DEFB121 | 0.763723 | 4 | 0 | 4 |
| KCNK9 | ATXN7L2 | 0.762765 | 3 | 0 | 3 |
| KCNK9 | OR2T27 | 0.761685 | 3 | 0 | 3 |
| KCNK9 | OPRD1 | 0.756862 | 3 | 0 | 3 |
| KCNK9 | ZNF852 | 0.752747 | 3 | 0 | 3 |
| KCNK9 | AANAT | 0.751601 | 3 | 0 | 3 |
| KCNK9 | OR4A15 | 0.750425 | 3 | 0 | 3 |
For details and further investigation, click here
