| Full name: opioid receptor delta 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1p35.3 | ||
| Entrez ID: 4985 | HGNC ID: HGNC:8153 | Ensembl Gene: ENSG00000116329 | OMIM ID: 165195 |
| Drug and gene relationship at DGIdb | |||
OPRD1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04022 | cGMP-PKG signaling pathway | |
| hsa04071 | Sphingolipid signaling pathway |
Expression of OPRD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OPRD1 | 4985 | 207792_at | -0.0055 | 0.9879 | |
| GSE20347 | OPRD1 | 4985 | 207792_at | -0.2019 | 0.0006 | |
| GSE23400 | OPRD1 | 4985 | 207792_at | -0.1853 | 0.0000 | |
| GSE26886 | OPRD1 | 4985 | 207792_at | 0.2335 | 0.0145 | |
| GSE29001 | OPRD1 | 4985 | 207792_at | -0.2405 | 0.1225 | |
| GSE38129 | OPRD1 | 4985 | 207792_at | -0.1654 | 0.0035 | |
| GSE45670 | OPRD1 | 4985 | 207792_at | -0.0327 | 0.7902 | |
| GSE53622 | OPRD1 | 4985 | 25665 | -0.0875 | 0.3068 | |
| GSE53624 | OPRD1 | 4985 | 25665 | -0.2249 | 0.0164 | |
| GSE63941 | OPRD1 | 4985 | 207792_at | 0.1252 | 0.5553 | |
| GSE77861 | OPRD1 | 4985 | 207792_at | -0.2569 | 0.0945 | |
| GSE97050 | OPRD1 | 4985 | A_33_P3272075 | -0.1064 | 0.6185 | |
| SRP007169 | OPRD1 | 4985 | RNAseq | 1.4144 | 0.0604 | |
| SRP064894 | OPRD1 | 4985 | RNAseq | 0.2120 | 0.3690 | |
| SRP133303 | OPRD1 | 4985 | RNAseq | 0.0119 | 0.9181 | |
| SRP193095 | OPRD1 | 4985 | RNAseq | 0.0038 | 0.9804 | |
| SRP219564 | OPRD1 | 4985 | RNAseq | 0.1349 | 0.6708 | |
| TCGA | OPRD1 | 4985 | RNAseq | -1.4344 | 0.3590 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by OPRD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OPRD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OPRD1 | 4985 | 0 | 6 | 24 | |
| GSE20123 | OPRD1 | 4985 | 0 | 5 | 25 | |
| GSE43470 | OPRD1 | 4985 | 3 | 6 | 34 | |
| GSE46452 | OPRD1 | 4985 | 5 | 1 | 53 | |
| GSE47630 | OPRD1 | 4985 | 8 | 3 | 29 | |
| GSE54993 | OPRD1 | 4985 | 2 | 1 | 67 | |
| GSE54994 | OPRD1 | 4985 | 10 | 4 | 39 | |
| GSE60625 | OPRD1 | 4985 | 0 | 0 | 11 | |
| GSE74703 | OPRD1 | 4985 | 2 | 4 | 30 | |
| GSE74704 | OPRD1 | 4985 | 0 | 0 | 20 | |
| TCGA | OPRD1 | 4985 | 11 | 21 | 64 |
Total number of gains: 41; Total number of losses: 51; Total Number of normals: 396.
Somatic mutations of OPRD1:
Generating mutation plots.
Highly correlated genes for OPRD1:
Showing top 20/925 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OPRD1 | GLTPD2 | 0.80732 | 3 | 0 | 3 |
| OPRD1 | CDH10 | 0.797423 | 3 | 0 | 3 |
| OPRD1 | TMEM179 | 0.764593 | 3 | 0 | 3 |
| OPRD1 | EYS | 0.76241 | 3 | 0 | 3 |
| OPRD1 | BSND | 0.75785 | 5 | 0 | 5 |
| OPRD1 | KCNK9 | 0.756862 | 3 | 0 | 3 |
| OPRD1 | LHX9 | 0.754301 | 3 | 0 | 3 |
| OPRD1 | CFC1 | 0.744713 | 3 | 0 | 3 |
| OPRD1 | TSPO2 | 0.741862 | 3 | 0 | 3 |
| OPRD1 | EPHA10 | 0.730414 | 4 | 0 | 4 |
| OPRD1 | CHRD | 0.728888 | 4 | 0 | 4 |
| OPRD1 | FAM71A | 0.724218 | 4 | 0 | 3 |
| OPRD1 | SLC16A11 | 0.722212 | 3 | 0 | 3 |
| OPRD1 | PGC | 0.72058 | 5 | 0 | 4 |
| OPRD1 | LCN8 | 0.719888 | 3 | 0 | 3 |
| OPRD1 | FMR1NB | 0.718786 | 3 | 0 | 3 |
| OPRD1 | CDC42EP2 | 0.714253 | 3 | 0 | 3 |
| OPRD1 | HINFP | 0.71349 | 3 | 0 | 3 |
| OPRD1 | SHANK1 | 0.71329 | 6 | 0 | 5 |
| OPRD1 | OSBPL5 | 0.711487 | 4 | 0 | 3 |
For details and further investigation, click here
