| Full name: ataxin 7 like 2 | Alias Symbol: MGC46534|FLJ00381 | ||
| Type: protein-coding gene | Cytoband: 1p13.3 | ||
| Entrez ID: 127002 | HGNC ID: HGNC:28713 | Ensembl Gene: ENSG00000162650 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ATXN7L2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ATXN7L2 | 127002 | 230038_at | 0.1873 | 0.5726 | |
| GSE26886 | ATXN7L2 | 127002 | 230038_at | 0.4095 | 0.0057 | |
| GSE45670 | ATXN7L2 | 127002 | 230038_at | 0.0686 | 0.3861 | |
| GSE53622 | ATXN7L2 | 127002 | 31109 | -0.0050 | 0.9409 | |
| GSE53624 | ATXN7L2 | 127002 | 31109 | 0.1095 | 0.0896 | |
| GSE63941 | ATXN7L2 | 127002 | 230038_at | 0.2727 | 0.1739 | |
| GSE77861 | ATXN7L2 | 127002 | 230038_at | 0.0019 | 0.9882 | |
| GSE97050 | ATXN7L2 | 127002 | A_23_P317207 | 0.1393 | 0.5537 | |
| SRP007169 | ATXN7L2 | 127002 | RNAseq | 0.6202 | 0.3274 | |
| SRP064894 | ATXN7L2 | 127002 | RNAseq | 0.8239 | 0.0001 | |
| SRP133303 | ATXN7L2 | 127002 | RNAseq | 0.2023 | 0.4329 | |
| SRP159526 | ATXN7L2 | 127002 | RNAseq | 0.6929 | 0.2339 | |
| SRP193095 | ATXN7L2 | 127002 | RNAseq | 0.3158 | 0.0187 | |
| SRP219564 | ATXN7L2 | 127002 | RNAseq | 0.7903 | 0.1240 | |
| TCGA | ATXN7L2 | 127002 | RNAseq | 0.2234 | 0.0171 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ATXN7L2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ATXN7L2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ATXN7L2 | 127002 | 0 | 12 | 18 | |
| GSE20123 | ATXN7L2 | 127002 | 0 | 11 | 19 | |
| GSE43470 | ATXN7L2 | 127002 | 0 | 8 | 35 | |
| GSE46452 | ATXN7L2 | 127002 | 2 | 1 | 56 | |
| GSE47630 | ATXN7L2 | 127002 | 9 | 5 | 26 | |
| GSE54993 | ATXN7L2 | 127002 | 0 | 1 | 69 | |
| GSE54994 | ATXN7L2 | 127002 | 7 | 4 | 42 | |
| GSE60625 | ATXN7L2 | 127002 | 0 | 0 | 11 | |
| GSE74703 | ATXN7L2 | 127002 | 0 | 6 | 30 | |
| GSE74704 | ATXN7L2 | 127002 | 0 | 7 | 13 | |
| TCGA | ATXN7L2 | 127002 | 8 | 26 | 62 |
Total number of gains: 26; Total number of losses: 81; Total Number of normals: 381.
Somatic mutations of ATXN7L2:
Generating mutation plots.
Highly correlated genes for ATXN7L2:
Showing top 20/182 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ATXN7L2 | PRAF2 | 0.776575 | 3 | 0 | 3 |
| ATXN7L2 | KCNK9 | 0.762765 | 3 | 0 | 3 |
| ATXN7L2 | FAM189B | 0.744882 | 3 | 0 | 3 |
| ATXN7L2 | SYCE1L | 0.743805 | 3 | 0 | 3 |
| ATXN7L2 | LRRC4 | 0.734194 | 3 | 0 | 3 |
| ATXN7L2 | REN | 0.733724 | 3 | 0 | 3 |
| ATXN7L2 | FOXB1 | 0.732091 | 3 | 0 | 3 |
| ATXN7L2 | RIMS4 | 0.730711 | 3 | 0 | 3 |
| ATXN7L2 | SLC27A5 | 0.721414 | 4 | 0 | 4 |
| ATXN7L2 | AIFM3 | 0.716396 | 3 | 0 | 3 |
| ATXN7L2 | CORT | 0.714399 | 3 | 0 | 3 |
| ATXN7L2 | FAM71F1 | 0.712215 | 3 | 0 | 3 |
| ATXN7L2 | TBX10 | 0.707591 | 3 | 0 | 3 |
| ATXN7L2 | CRYAA | 0.706964 | 3 | 0 | 3 |
| ATXN7L2 | ZNRF4 | 0.702184 | 3 | 0 | 3 |
| ATXN7L2 | CNOT3 | 0.701456 | 4 | 0 | 4 |
| ATXN7L2 | TRPM8 | 0.695797 | 3 | 0 | 3 |
| ATXN7L2 | LRFN1 | 0.694803 | 4 | 0 | 4 |
| ATXN7L2 | ABCA2 | 0.688726 | 4 | 0 | 3 |
| ATXN7L2 | FFAR1 | 0.68802 | 4 | 0 | 3 |
For details and further investigation, click here
