| Full name: forkhead box E3 | Alias Symbol: FREAC8 | ||
| Type: protein-coding gene | Cytoband: 1p33 | ||
| Entrez ID: 2301 | HGNC ID: HGNC:3808 | Ensembl Gene: ENSG00000186790 | OMIM ID: 601094 |
| Drug and gene relationship at DGIdb | |||
Expression of FOXE3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FOXE3 | 2301 | 220621_at | 0.1415 | 0.5416 | |
| GSE20347 | FOXE3 | 2301 | 220621_at | -0.0198 | 0.7629 | |
| GSE23400 | FOXE3 | 2301 | 220621_at | -0.0714 | 0.0078 | |
| GSE26886 | FOXE3 | 2301 | 220621_at | -0.0019 | 0.9888 | |
| GSE29001 | FOXE3 | 2301 | 220621_at | 0.1131 | 0.3843 | |
| GSE38129 | FOXE3 | 2301 | 220621_at | -0.0591 | 0.3383 | |
| GSE45670 | FOXE3 | 2301 | 220621_at | 0.1582 | 0.2230 | |
| GSE53622 | FOXE3 | 2301 | 8396 | 0.2266 | 0.0069 | |
| GSE53624 | FOXE3 | 2301 | 8396 | 0.0993 | 0.4131 | |
| GSE63941 | FOXE3 | 2301 | 220621_at | -0.0868 | 0.5228 | |
| GSE77861 | FOXE3 | 2301 | 220621_at | -0.0151 | 0.9219 | |
| GSE97050 | FOXE3 | 2301 | A_23_P112666 | -0.2377 | 0.4612 | |
| TCGA | FOXE3 | 2301 | RNAseq | 3.1556 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by FOXE3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FOXE3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FOXE3 | 2301 | 4 | 3 | 23 | |
| GSE20123 | FOXE3 | 2301 | 4 | 2 | 24 | |
| GSE43470 | FOXE3 | 2301 | 5 | 1 | 37 | |
| GSE46452 | FOXE3 | 2301 | 2 | 1 | 56 | |
| GSE47630 | FOXE3 | 2301 | 8 | 4 | 28 | |
| GSE54993 | FOXE3 | 2301 | 0 | 1 | 69 | |
| GSE54994 | FOXE3 | 2301 | 11 | 2 | 40 | |
| GSE60625 | FOXE3 | 2301 | 0 | 0 | 11 | |
| GSE74703 | FOXE3 | 2301 | 4 | 1 | 31 | |
| GSE74704 | FOXE3 | 2301 | 2 | 0 | 18 | |
| TCGA | FOXE3 | 2301 | 10 | 17 | 69 |
Total number of gains: 50; Total number of losses: 32; Total Number of normals: 406.
Somatic mutations of FOXE3:
Generating mutation plots.
Highly correlated genes for FOXE3:
Showing top 20/553 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FOXE3 | WDR87 | 0.902633 | 3 | 0 | 3 |
| FOXE3 | STRC | 0.876843 | 3 | 0 | 3 |
| FOXE3 | PLA2G2C | 0.871876 | 3 | 0 | 3 |
| FOXE3 | FBRSL1 | 0.869305 | 3 | 0 | 3 |
| FOXE3 | DCDC1 | 0.864655 | 3 | 0 | 3 |
| FOXE3 | YY2 | 0.85042 | 3 | 0 | 3 |
| FOXE3 | KRTAP10-12 | 0.83824 | 3 | 0 | 3 |
| FOXE3 | KRTAP2-1 | 0.830213 | 3 | 0 | 3 |
| FOXE3 | FAM131A | 0.829804 | 3 | 0 | 3 |
| FOXE3 | C9orf153 | 0.827544 | 3 | 0 | 3 |
| FOXE3 | BBC3 | 0.81969 | 3 | 0 | 3 |
| FOXE3 | KIRREL2 | 0.817372 | 3 | 0 | 3 |
| FOXE3 | ST8SIA1 | 0.815382 | 3 | 0 | 3 |
| FOXE3 | RNF180 | 0.814479 | 3 | 0 | 3 |
| FOXE3 | OR2T27 | 0.813337 | 3 | 0 | 3 |
| FOXE3 | OR2A5 | 0.81237 | 3 | 0 | 3 |
| FOXE3 | SLC26A1 | 0.812342 | 4 | 0 | 4 |
| FOXE3 | ZNF527 | 0.808386 | 4 | 0 | 4 |
| FOXE3 | OR2T1 | 0.807393 | 3 | 0 | 3 |
| FOXE3 | MRGPRG | 0.805514 | 3 | 0 | 3 |
For details and further investigation, click here
