| Full name: kelch like family member 4 | Alias Symbol: KIAA1687|DKELCHL|KHL4 | ||
| Type: protein-coding gene | Cytoband: Xq21.31 | ||
| Entrez ID: 56062 | HGNC ID: HGNC:6355 | Ensembl Gene: ENSG00000102271 | OMIM ID: 300348 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of KLHL4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KLHL4 | 56062 | 1553027_a_at | -0.1616 | 0.4437 | |
| GSE20347 | KLHL4 | 56062 | 214591_at | 0.0821 | 0.2353 | |
| GSE23400 | KLHL4 | 56062 | 214591_at | -0.0520 | 0.1223 | |
| GSE26886 | KLHL4 | 56062 | 1553027_a_at | -0.1702 | 0.1704 | |
| GSE29001 | KLHL4 | 56062 | 214591_at | -0.1284 | 0.3626 | |
| GSE38129 | KLHL4 | 56062 | 214591_at | -0.0131 | 0.8926 | |
| GSE45670 | KLHL4 | 56062 | 1553027_a_at | 0.1221 | 0.4327 | |
| GSE53622 | KLHL4 | 56062 | 115820 | -0.4301 | 0.0096 | |
| GSE53624 | KLHL4 | 56062 | 115820 | 0.1717 | 0.2500 | |
| GSE63941 | KLHL4 | 56062 | 1553027_a_at | 0.1241 | 0.4208 | |
| GSE77861 | KLHL4 | 56062 | 1553027_a_at | -0.0146 | 0.9009 | |
| SRP133303 | KLHL4 | 56062 | RNAseq | -0.2026 | 0.4839 | |
| SRP159526 | KLHL4 | 56062 | RNAseq | 1.7281 | 0.0431 | |
| TCGA | KLHL4 | 56062 | RNAseq | -0.2206 | 0.6248 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by KLHL4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KLHL4:
No record found for this gene.
Somatic mutations of KLHL4:
Generating mutation plots.
Highly correlated genes for KLHL4:
Showing top 20/199 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KLHL4 | CTRC | 0.730641 | 3 | 0 | 3 |
| KLHL4 | MATN1 | 0.709423 | 4 | 0 | 4 |
| KLHL4 | ABCB11 | 0.687477 | 3 | 0 | 3 |
| KLHL4 | SLC28A2 | 0.675038 | 3 | 0 | 3 |
| KLHL4 | CLCN4 | 0.669037 | 3 | 0 | 3 |
| KLHL4 | CD5L | 0.666197 | 3 | 0 | 3 |
| KLHL4 | MAGEB4 | 0.661597 | 4 | 0 | 4 |
| KLHL4 | SNTG1 | 0.659267 | 3 | 0 | 3 |
| KLHL4 | CRLF2 | 0.654448 | 4 | 0 | 4 |
| KLHL4 | ART1 | 0.653984 | 3 | 0 | 3 |
| KLHL4 | S100G | 0.652505 | 3 | 0 | 3 |
| KLHL4 | TMSB4Y | 0.646433 | 3 | 0 | 3 |
| KLHL4 | PRLR | 0.643843 | 3 | 0 | 3 |
| KLHL4 | CA8 | 0.642544 | 3 | 0 | 3 |
| KLHL4 | NR1I3 | 0.639565 | 3 | 0 | 3 |
| KLHL4 | IFNA10 | 0.638525 | 4 | 0 | 4 |
| KLHL4 | CSN2 | 0.636969 | 4 | 0 | 4 |
| KLHL4 | GLYAT | 0.636149 | 3 | 0 | 3 |
| KLHL4 | ZNF460 | 0.635819 | 3 | 0 | 3 |
| KLHL4 | GH2 | 0.630637 | 4 | 0 | 4 |
For details and further investigation, click here
