| Full name: nuclear receptor subfamily 1 group I member 3 | Alias Symbol: MB67|CAR1|CAR | ||
| Type: protein-coding gene | Cytoband: 1q23.3 | ||
| Entrez ID: 9970 | HGNC ID: HGNC:7969 | Ensembl Gene: ENSG00000143257 | OMIM ID: 603881 |
| Drug and gene relationship at DGIdb | |||
Expression of NR1I3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NR1I3 | 9970 | 207007_at | -0.1368 | 0.5963 | |
| GSE20347 | NR1I3 | 9970 | 207007_at | -0.1378 | 0.0854 | |
| GSE23400 | NR1I3 | 9970 | 207007_at | -0.2693 | 0.0000 | |
| GSE26886 | NR1I3 | 9970 | 207007_at | -0.1720 | 0.0938 | |
| GSE29001 | NR1I3 | 9970 | 207007_at | -0.2421 | 0.1367 | |
| GSE38129 | NR1I3 | 9970 | 207007_at | -0.1737 | 0.0163 | |
| GSE45670 | NR1I3 | 9970 | 207007_at | -0.0058 | 0.9613 | |
| GSE53622 | NR1I3 | 9970 | 46630 | 0.2118 | 0.1087 | |
| GSE53624 | NR1I3 | 9970 | 46630 | 0.2411 | 0.0008 | |
| GSE63941 | NR1I3 | 9970 | 207007_at | -0.1228 | 0.3893 | |
| GSE77861 | NR1I3 | 9970 | 207007_at | -0.1344 | 0.2591 | |
| GSE97050 | NR1I3 | 9970 | A_23_P319572 | -0.3165 | 0.3484 | |
| SRP159526 | NR1I3 | 9970 | RNAseq | 1.1984 | 0.0611 | |
| TCGA | NR1I3 | 9970 | RNAseq | 0.1067 | 0.7034 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NR1I3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NR1I3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NR1I3 | 9970 | 10 | 0 | 20 | |
| GSE20123 | NR1I3 | 9970 | 10 | 0 | 20 | |
| GSE43470 | NR1I3 | 9970 | 7 | 2 | 34 | |
| GSE46452 | NR1I3 | 9970 | 2 | 1 | 56 | |
| GSE47630 | NR1I3 | 9970 | 14 | 0 | 26 | |
| GSE54993 | NR1I3 | 9970 | 0 | 6 | 64 | |
| GSE54994 | NR1I3 | 9970 | 16 | 0 | 37 | |
| GSE60625 | NR1I3 | 9970 | 0 | 0 | 11 | |
| GSE74703 | NR1I3 | 9970 | 7 | 2 | 27 | |
| GSE74704 | NR1I3 | 9970 | 4 | 0 | 16 | |
| TCGA | NR1I3 | 9970 | 45 | 3 | 48 |
Total number of gains: 115; Total number of losses: 14; Total Number of normals: 359.
Somatic mutations of NR1I3:
Generating mutation plots.
Highly correlated genes for NR1I3:
Showing top 20/747 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NR1I3 | PTAFR | 0.737905 | 3 | 0 | 3 |
| NR1I3 | SRCAP | 0.734413 | 3 | 0 | 3 |
| NR1I3 | GRIN2C | 0.718172 | 4 | 0 | 4 |
| NR1I3 | CABP1 | 0.71115 | 3 | 0 | 3 |
| NR1I3 | NPPA | 0.695549 | 4 | 0 | 4 |
| NR1I3 | EVX1 | 0.693081 | 4 | 0 | 4 |
| NR1I3 | MYL7 | 0.69247 | 5 | 0 | 4 |
| NR1I3 | SLC5A5 | 0.688342 | 5 | 0 | 5 |
| NR1I3 | LCN8 | 0.68384 | 4 | 0 | 3 |
| NR1I3 | FCN2 | 0.681193 | 4 | 0 | 4 |
| NR1I3 | DCD | 0.677536 | 3 | 0 | 3 |
| NR1I3 | TCP10L | 0.676589 | 4 | 0 | 4 |
| NR1I3 | GFRA2 | 0.675861 | 6 | 0 | 5 |
| NR1I3 | KCNJ4 | 0.6755 | 3 | 0 | 3 |
| NR1I3 | ADCY1 | 0.672087 | 3 | 0 | 3 |
| NR1I3 | PRL | 0.669672 | 5 | 0 | 5 |
| NR1I3 | SLC26A1 | 0.66927 | 4 | 0 | 3 |
| NR1I3 | POU4F3 | 0.669227 | 4 | 0 | 4 |
| NR1I3 | CA5A | 0.668097 | 6 | 0 | 4 |
| NR1I3 | OR7C2 | 0.666827 | 4 | 0 | 3 |
For details and further investigation, click here
