| Full name: matrilin 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1p35.2 | ||
| Entrez ID: 4146 | HGNC ID: HGNC:6907 | Ensembl Gene: ENSG00000162510 | OMIM ID: 115437 |
| Drug and gene relationship at DGIdb | |||
Expression of MATN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MATN1 | 4146 | 206904_at | -0.1624 | 0.6186 | |
| GSE20347 | MATN1 | 4146 | 206905_s_at | -0.0034 | 0.9615 | |
| GSE23400 | MATN1 | 4146 | 206904_at | -0.2526 | 0.0000 | |
| GSE26886 | MATN1 | 4146 | 206904_at | -0.1812 | 0.1701 | |
| GSE29001 | MATN1 | 4146 | 206904_at | -0.2707 | 0.2910 | |
| GSE38129 | MATN1 | 4146 | 206905_s_at | 0.0104 | 0.8658 | |
| GSE45670 | MATN1 | 4146 | 206905_s_at | 0.2069 | 0.0503 | |
| GSE53622 | MATN1 | 4146 | 74340 | -0.0041 | 0.9553 | |
| GSE53624 | MATN1 | 4146 | 74340 | -0.1711 | 0.0448 | |
| GSE63941 | MATN1 | 4146 | 206905_s_at | 0.1550 | 0.3144 | |
| GSE77861 | MATN1 | 4146 | 206905_s_at | -0.1454 | 0.1870 | |
| GSE97050 | MATN1 | 4146 | A_23_P97677 | 0.1001 | 0.6187 | |
| SRP133303 | MATN1 | 4146 | RNAseq | 0.2573 | 0.3195 | |
| TCGA | MATN1 | 4146 | RNAseq | -0.0995 | 0.8533 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MATN1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MATN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MATN1 | 4146 | 0 | 6 | 24 | |
| GSE20123 | MATN1 | 4146 | 0 | 5 | 25 | |
| GSE43470 | MATN1 | 4146 | 3 | 6 | 34 | |
| GSE46452 | MATN1 | 4146 | 5 | 1 | 53 | |
| GSE47630 | MATN1 | 4146 | 8 | 3 | 29 | |
| GSE54993 | MATN1 | 4146 | 1 | 1 | 68 | |
| GSE54994 | MATN1 | 4146 | 10 | 3 | 40 | |
| GSE60625 | MATN1 | 4146 | 0 | 0 | 11 | |
| GSE74703 | MATN1 | 4146 | 2 | 4 | 30 | |
| GSE74704 | MATN1 | 4146 | 0 | 0 | 20 | |
| TCGA | MATN1 | 4146 | 13 | 18 | 65 |
Total number of gains: 42; Total number of losses: 47; Total Number of normals: 399.
Somatic mutations of MATN1:
Generating mutation plots.
Highly correlated genes for MATN1:
Showing top 20/779 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MATN1 | PRAMEF12 | 0.776486 | 4 | 0 | 4 |
| MATN1 | NSUN7 | 0.762301 | 3 | 0 | 3 |
| MATN1 | IQCF3 | 0.743686 | 3 | 0 | 3 |
| MATN1 | SRCAP | 0.731066 | 3 | 0 | 3 |
| MATN1 | PKDREJ | 0.724252 | 3 | 0 | 3 |
| MATN1 | TMEM184A | 0.719016 | 4 | 0 | 4 |
| MATN1 | TULP2 | 0.715789 | 5 | 0 | 4 |
| MATN1 | SPACA3 | 0.7138 | 3 | 0 | 3 |
| MATN1 | C16orf82 | 0.71229 | 3 | 0 | 3 |
| MATN1 | ZNRF4 | 0.712079 | 3 | 0 | 3 |
| MATN1 | KLHL4 | 0.709423 | 4 | 0 | 4 |
| MATN1 | NR1H4 | 0.708444 | 3 | 0 | 3 |
| MATN1 | LDHAL6A | 0.708333 | 3 | 0 | 3 |
| MATN1 | ANKRD53 | 0.708282 | 3 | 0 | 3 |
| MATN1 | FRMPD1 | 0.706283 | 4 | 0 | 3 |
| MATN1 | ABCC6 | 0.706214 | 3 | 0 | 3 |
| MATN1 | PGLYRP1 | 0.704786 | 4 | 0 | 3 |
| MATN1 | PAPOLB | 0.704238 | 3 | 0 | 3 |
| MATN1 | C6orf15 | 0.7041 | 3 | 0 | 3 |
| MATN1 | IFNA4 | 0.703757 | 6 | 0 | 5 |
For details and further investigation, click here
