| Full name: keratin 23 | Alias Symbol: K23|DKFZP434G032|HAIK1|CK23|MGC26158 | ||
| Type: protein-coding gene | Cytoband: 17q21.2 | ||
| Entrez ID: 25984 | HGNC ID: HGNC:6438 | Ensembl Gene: ENSG00000108244 | OMIM ID: 606194 |
| Drug and gene relationship at DGIdb | |||
Expression of KRT23:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KRT23 | 25984 | 218963_s_at | -1.2711 | 0.2311 | |
| GSE20347 | KRT23 | 25984 | 218963_s_at | 0.3726 | 0.5480 | |
| GSE23400 | KRT23 | 25984 | 218963_s_at | -0.0450 | 0.8645 | |
| GSE26886 | KRT23 | 25984 | 218963_s_at | -0.3578 | 0.5942 | |
| GSE29001 | KRT23 | 25984 | 218963_s_at | 0.8366 | 0.3123 | |
| GSE38129 | KRT23 | 25984 | 218963_s_at | 0.7706 | 0.1428 | |
| GSE45670 | KRT23 | 25984 | 218963_s_at | 1.6939 | 0.0225 | |
| GSE53622 | KRT23 | 25984 | 62907 | 0.3453 | 0.3546 | |
| GSE53624 | KRT23 | 25984 | 62907 | -0.4470 | 0.0587 | |
| GSE63941 | KRT23 | 25984 | 218963_s_at | 1.7007 | 0.2587 | |
| GSE77861 | KRT23 | 25984 | 218963_s_at | 0.2898 | 0.8228 | |
| GSE97050 | KRT23 | 25984 | A_23_P78248 | 0.8133 | 0.2216 | |
| SRP007169 | KRT23 | 25984 | RNAseq | 1.2596 | 0.1644 | |
| SRP064894 | KRT23 | 25984 | RNAseq | -0.1674 | 0.8205 | |
| SRP133303 | KRT23 | 25984 | RNAseq | -0.5731 | 0.2039 | |
| SRP159526 | KRT23 | 25984 | RNAseq | 0.8105 | 0.4163 | |
| SRP219564 | KRT23 | 25984 | RNAseq | -1.0207 | 0.3496 | |
| TCGA | KRT23 | 25984 | RNAseq | 1.1159 | 0.0019 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by KRT23 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KRT23:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KRT23 | 25984 | 7 | 1 | 22 | |
| GSE20123 | KRT23 | 25984 | 7 | 1 | 22 | |
| GSE43470 | KRT23 | 25984 | 1 | 2 | 40 | |
| GSE46452 | KRT23 | 25984 | 34 | 0 | 25 | |
| GSE47630 | KRT23 | 25984 | 8 | 1 | 31 | |
| GSE54993 | KRT23 | 25984 | 3 | 4 | 63 | |
| GSE54994 | KRT23 | 25984 | 8 | 5 | 40 | |
| GSE60625 | KRT23 | 25984 | 4 | 0 | 7 | |
| GSE74703 | KRT23 | 25984 | 1 | 1 | 34 | |
| GSE74704 | KRT23 | 25984 | 5 | 1 | 14 | |
| TCGA | KRT23 | 25984 | 22 | 8 | 66 |
Total number of gains: 100; Total number of losses: 24; Total Number of normals: 364.
Somatic mutations of KRT23:
Generating mutation plots.
Highly correlated genes for KRT23:
Showing all 13 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KRT23 | KLK12 | 0.612405 | 3 | 0 | 3 |
| KRT23 | POLH | 0.606274 | 3 | 0 | 3 |
| KRT23 | TFF3 | 0.597427 | 3 | 0 | 3 |
| KRT23 | SLC6A14 | 0.574793 | 7 | 0 | 4 |
| KRT23 | SPNS2 | 0.574084 | 3 | 0 | 3 |
| KRT23 | SLC25A19 | 0.558813 | 4 | 0 | 4 |
| KRT23 | ST6GAL1 | 0.555802 | 5 | 0 | 3 |
| KRT23 | KRT80 | 0.546743 | 6 | 0 | 4 |
| KRT23 | QPCT | 0.544866 | 6 | 0 | 4 |
| KRT23 | LACTB2 | 0.512567 | 4 | 0 | 3 |
| KRT23 | RNF183 | 0.504789 | 5 | 0 | 3 |
| KRT23 | S100A7 | 0.504071 | 7 | 0 | 4 |
| KRT23 | SLC5A1 | 0.502649 | 7 | 0 | 3 |
For details and further investigation, click here
