| Full name: glutaminyl-peptide cyclotransferase | Alias Symbol: QC|GCT | ||
| Type: protein-coding gene | Cytoband: 2p22.2 | ||
| Entrez ID: 25797 | HGNC ID: HGNC:9753 | Ensembl Gene: ENSG00000115828 | OMIM ID: 607065 |
| Drug and gene relationship at DGIdb | |||
Expression of QPCT:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | QPCT | 25797 | 205174_s_at | -0.4255 | 0.7295 | |
| GSE20347 | QPCT | 25797 | 205174_s_at | 0.1230 | 0.7341 | |
| GSE23400 | QPCT | 25797 | 205174_s_at | 0.0901 | 0.2204 | |
| GSE26886 | QPCT | 25797 | 205174_s_at | -0.1113 | 0.8473 | |
| GSE29001 | QPCT | 25797 | 205174_s_at | 0.4639 | 0.3996 | |
| GSE38129 | QPCT | 25797 | 205174_s_at | 0.6418 | 0.0559 | |
| GSE45670 | QPCT | 25797 | 205174_s_at | 0.8611 | 0.0415 | |
| GSE53622 | QPCT | 25797 | 94497 | 0.6406 | 0.0021 | |
| GSE53624 | QPCT | 25797 | 94497 | 0.1161 | 0.5926 | |
| GSE63941 | QPCT | 25797 | 205174_s_at | -1.8564 | 0.3281 | |
| GSE77861 | QPCT | 25797 | 205174_s_at | -0.2424 | 0.6479 | |
| GSE97050 | QPCT | 25797 | A_23_P16915 | 0.7888 | 0.2736 | |
| SRP007169 | QPCT | 25797 | RNAseq | 1.3267 | 0.1176 | |
| SRP064894 | QPCT | 25797 | RNAseq | 1.1707 | 0.0005 | |
| SRP133303 | QPCT | 25797 | RNAseq | 0.3617 | 0.0334 | |
| SRP159526 | QPCT | 25797 | RNAseq | 0.6242 | 0.1551 | |
| SRP193095 | QPCT | 25797 | RNAseq | 0.8831 | 0.0001 | |
| SRP219564 | QPCT | 25797 | RNAseq | -1.3251 | 0.0150 | |
| TCGA | QPCT | 25797 | RNAseq | 0.7335 | 0.0002 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by QPCT expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of QPCT:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | QPCT | 25797 | 10 | 1 | 19 | |
| GSE20123 | QPCT | 25797 | 9 | 1 | 20 | |
| GSE43470 | QPCT | 25797 | 3 | 0 | 40 | |
| GSE46452 | QPCT | 25797 | 1 | 4 | 54 | |
| GSE47630 | QPCT | 25797 | 7 | 0 | 33 | |
| GSE54993 | QPCT | 25797 | 0 | 5 | 65 | |
| GSE54994 | QPCT | 25797 | 10 | 0 | 43 | |
| GSE60625 | QPCT | 25797 | 0 | 3 | 8 | |
| GSE74703 | QPCT | 25797 | 3 | 0 | 33 | |
| GSE74704 | QPCT | 25797 | 9 | 1 | 10 | |
| TCGA | QPCT | 25797 | 35 | 2 | 59 |
Total number of gains: 87; Total number of losses: 17; Total Number of normals: 384.
Somatic mutations of QPCT:
Generating mutation plots.
Highly correlated genes for QPCT:
Showing top 20/44 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| QPCT | KLK6 | 0.714726 | 3 | 0 | 3 |
| QPCT | QPRT | 0.622823 | 4 | 0 | 3 |
| QPCT | CCR2 | 0.621268 | 3 | 0 | 3 |
| QPCT | BCL2A1 | 0.617055 | 6 | 0 | 4 |
| QPCT | SLC28A3 | 0.609646 | 3 | 0 | 3 |
| QPCT | SNCAIP | 0.600937 | 4 | 0 | 3 |
| QPCT | ZMYM6 | 0.599114 | 3 | 0 | 3 |
| QPCT | SLC6A14 | 0.598225 | 6 | 0 | 4 |
| QPCT | TSPAN3 | 0.592152 | 4 | 0 | 3 |
| QPCT | HSD17B2 | 0.591938 | 8 | 0 | 6 |
| QPCT | INHBE | 0.585972 | 3 | 0 | 3 |
| QPCT | MYCN | 0.585579 | 6 | 0 | 4 |
| QPCT | PLRG1 | 0.582122 | 4 | 0 | 3 |
| QPCT | MFSD10 | 0.579644 | 3 | 0 | 3 |
| QPCT | COL8A2 | 0.578834 | 6 | 0 | 4 |
| QPCT | RPA2 | 0.575328 | 5 | 0 | 4 |
| QPCT | TLR1 | 0.574939 | 6 | 0 | 4 |
| QPCT | LMO2 | 0.559473 | 3 | 0 | 3 |
| QPCT | CHI3L2 | 0.556821 | 8 | 0 | 5 |
| QPCT | CD247 | 0.554999 | 4 | 0 | 3 |
For details and further investigation, click here
