| Full name: S100 calcium binding protein A7 | Alias Symbol: S100A7c | ||
| Type: protein-coding gene | Cytoband: 1q21.3 | ||
| Entrez ID: 6278 | HGNC ID: HGNC:10497 | Ensembl Gene: ENSG00000143556 | OMIM ID: 600353 |
| Drug and gene relationship at DGIdb | |||
Expression of S100A7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | S100A7 | 6278 | 205916_at | 0.7788 | 0.7342 | |
| GSE20347 | S100A7 | 6278 | 205916_at | 1.0149 | 0.3881 | |
| GSE23400 | S100A7 | 6278 | 205916_at | 0.6497 | 0.1890 | |
| GSE26886 | S100A7 | 6278 | 205916_at | -1.6273 | 0.2380 | |
| GSE29001 | S100A7 | 6278 | 205916_at | 1.5506 | 0.1805 | |
| GSE38129 | S100A7 | 6278 | 205916_at | 1.6595 | 0.0724 | |
| GSE45670 | S100A7 | 6278 | 205916_at | 6.4962 | 0.0000 | |
| GSE53622 | S100A7 | 6278 | 19936 | 2.1129 | 0.0000 | |
| GSE53624 | S100A7 | 6278 | 19936 | 1.3422 | 0.0000 | |
| GSE63941 | S100A7 | 6278 | 205916_at | 1.5203 | 0.4270 | |
| GSE77861 | S100A7 | 6278 | 205916_at | 0.6546 | 0.5550 | |
| GSE97050 | S100A7 | 6278 | A_23_P103310 | 3.3584 | 0.0901 | |
| SRP007169 | S100A7 | 6278 | RNAseq | -0.6470 | 0.7491 | |
| SRP008496 | S100A7 | 6278 | RNAseq | -1.4785 | 0.3510 | |
| SRP064894 | S100A7 | 6278 | RNAseq | 2.7585 | 0.0010 | |
| SRP133303 | S100A7 | 6278 | RNAseq | 1.2033 | 0.3101 | |
| SRP159526 | S100A7 | 6278 | RNAseq | 1.5310 | 0.2689 | |
| TCGA | S100A7 | 6278 | RNAseq | 2.1872 | 0.0000 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by S100A7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of S100A7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | S100A7 | 6278 | 14 | 0 | 16 | |
| GSE20123 | S100A7 | 6278 | 14 | 0 | 16 | |
| GSE43470 | S100A7 | 6278 | 6 | 2 | 35 | |
| GSE46452 | S100A7 | 6278 | 2 | 1 | 56 | |
| GSE47630 | S100A7 | 6278 | 15 | 0 | 25 | |
| GSE54993 | S100A7 | 6278 | 0 | 4 | 66 | |
| GSE54994 | S100A7 | 6278 | 16 | 0 | 37 | |
| GSE60625 | S100A7 | 6278 | 0 | 0 | 11 | |
| GSE74703 | S100A7 | 6278 | 6 | 1 | 29 | |
| GSE74704 | S100A7 | 6278 | 7 | 0 | 13 | |
| TCGA | S100A7 | 6278 | 40 | 2 | 54 |
Total number of gains: 120; Total number of losses: 10; Total Number of normals: 358.
Somatic mutations of S100A7:
Generating mutation plots.
Highly correlated genes for S100A7:
Showing top 20/146 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| S100A7 | S100A7A | 0.79782 | 5 | 0 | 5 |
| S100A7 | ZNF821 | 0.671932 | 3 | 0 | 3 |
| S100A7 | RCC2 | 0.654441 | 3 | 0 | 3 |
| S100A7 | CEACAM19 | 0.647493 | 6 | 0 | 5 |
| S100A7 | CDCA8 | 0.640625 | 3 | 0 | 3 |
| S100A7 | BCL11B | 0.640419 | 6 | 0 | 5 |
| S100A7 | KRT16 | 0.635818 | 11 | 0 | 9 |
| S100A7 | IL36G | 0.634306 | 11 | 0 | 10 |
| S100A7 | TMEM167A | 0.629085 | 4 | 0 | 3 |
| S100A7 | PLA2G4E | 0.629015 | 3 | 0 | 3 |
| S100A7 | TMEM45A | 0.622904 | 10 | 0 | 8 |
| S100A7 | PSMD14 | 0.618288 | 3 | 0 | 3 |
| S100A7 | EPHB2 | 0.61501 | 4 | 0 | 3 |
| S100A7 | KRTDAP | 0.613449 | 8 | 0 | 6 |
| S100A7 | C14orf119 | 0.610379 | 3 | 0 | 3 |
| S100A7 | PDZK1IP1 | 0.607895 | 11 | 0 | 8 |
| S100A7 | MMP9 | 0.607582 | 4 | 0 | 3 |
| S100A7 | CLEC7A | 0.603509 | 5 | 0 | 4 |
| S100A7 | SLC28A3 | 0.598514 | 11 | 0 | 8 |
| S100A7 | KLK4 | 0.5964 | 4 | 0 | 3 |
For details and further investigation, click here
